| Full name: insulin like 4 | Alias Symbol: EPIL | ||
| Type: protein-coding gene | Cytoband: 9p24.1 | ||
| Entrez ID: 3641 | HGNC ID: HGNC:6087 | Ensembl Gene: ENSG00000120211 | OMIM ID: 600910 |
| Drug and gene relationship at DGIdb | |||
Expression of INSL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INSL4 | 3641 | 206549_at | 0.0616 | 0.7379 | |
| GSE20347 | INSL4 | 3641 | 206549_at | -0.1402 | 0.0294 | |
| GSE23400 | INSL4 | 3641 | 206549_at | -0.1096 | 0.0002 | |
| GSE26886 | INSL4 | 3641 | 206549_at | -0.2504 | 0.0249 | |
| GSE29001 | INSL4 | 3641 | 206549_at | -0.1445 | 0.1722 | |
| GSE38129 | INSL4 | 3641 | 206549_at | -0.1852 | 0.0038 | |
| GSE45670 | INSL4 | 3641 | 206549_at | -0.0645 | 0.3577 | |
| GSE53622 | INSL4 | 3641 | 56262 | 0.4457 | 0.0040 | |
| GSE53624 | INSL4 | 3641 | 56262 | 0.8057 | 0.0000 | |
| GSE63941 | INSL4 | 3641 | 206549_at | 0.3199 | 0.7047 | |
| GSE77861 | INSL4 | 3641 | 206549_at | -0.0582 | 0.5576 | |
| SRP133303 | INSL4 | 3641 | RNAseq | 0.2697 | 0.3692 | |
| SRP193095 | INSL4 | 3641 | RNAseq | -0.1907 | 0.2472 | |
| TCGA | INSL4 | 3641 | RNAseq | 2.4511 | 0.2090 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INSL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INSL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INSL4 | 3641 | 1 | 17 | 12 | |
| GSE20123 | INSL4 | 3641 | 1 | 16 | 13 | |
| GSE43470 | INSL4 | 3641 | 5 | 11 | 27 | |
| GSE46452 | INSL4 | 3641 | 2 | 23 | 34 | |
| GSE47630 | INSL4 | 3641 | 5 | 26 | 9 | |
| GSE54993 | INSL4 | 3641 | 6 | 3 | 61 | |
| GSE54994 | INSL4 | 3641 | 9 | 17 | 27 | |
| GSE60625 | INSL4 | 3641 | 0 | 2 | 9 | |
| GSE74703 | INSL4 | 3641 | 5 | 8 | 23 | |
| GSE74704 | INSL4 | 3641 | 0 | 12 | 8 | |
| TCGA | INSL4 | 3641 | 14 | 50 | 32 |
Total number of gains: 48; Total number of losses: 185; Total Number of normals: 255.
Somatic mutations of INSL4:
Generating mutation plots.
Highly correlated genes for INSL4:
Showing top 20/373 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INSL4 | GNB2 | 0.6743 | 3 | 0 | 3 |
| INSL4 | SERPINA5 | 0.63998 | 3 | 0 | 3 |
| INSL4 | C9orf16 | 0.639117 | 3 | 0 | 3 |
| INSL4 | CYP3A4 | 0.634508 | 4 | 0 | 3 |
| INSL4 | GPR21 | 0.632627 | 3 | 0 | 3 |
| INSL4 | PCSK6 | 0.628738 | 4 | 0 | 3 |
| INSL4 | SLC13A3 | 0.628445 | 6 | 0 | 5 |
| INSL4 | SLC25A39 | 0.627542 | 3 | 0 | 3 |
| INSL4 | FBXL8 | 0.627284 | 3 | 0 | 3 |
| INSL4 | NHLRC4 | 0.626639 | 3 | 0 | 3 |
| INSL4 | SLC10A1 | 0.625039 | 3 | 0 | 3 |
| INSL4 | ARPC4 | 0.617597 | 3 | 0 | 3 |
| INSL4 | C11orf16 | 0.616886 | 4 | 0 | 4 |
| INSL4 | OR2H2 | 0.616545 | 6 | 0 | 6 |
| INSL4 | TAAR2 | 0.611916 | 3 | 0 | 3 |
| INSL4 | SLC18A1 | 0.610586 | 5 | 0 | 4 |
| INSL4 | OR10H3 | 0.606647 | 4 | 0 | 4 |
| INSL4 | MC2R | 0.605474 | 4 | 0 | 4 |
| INSL4 | GJB4 | 0.604947 | 5 | 0 | 4 |
| INSL4 | ARHGAP44 | 0.604599 | 5 | 0 | 3 |
For details and further investigation, click here
