| Full name: potassium two pore domain channel subfamily K member 15 | Alias Symbol: K2p15.1|dJ781B1.1|KT3.3|KIAA0237|TASK5|TASK-5 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 60598 | HGNC ID: HGNC:13814 | Ensembl Gene: ENSG00000124249 | OMIM ID: 607368 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNK15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNK15 | 60598 | 1560620_at | -0.0215 | 0.9567 | |
| GSE20347 | KCNK15 | 60598 | 220540_at | 0.0269 | 0.6643 | |
| GSE23400 | KCNK15 | 60598 | 220540_at | -0.0177 | 0.5421 | |
| GSE26886 | KCNK15 | 60598 | 1560620_at | -0.0441 | 0.7825 | |
| GSE29001 | KCNK15 | 60598 | 220540_at | -0.1774 | 0.2898 | |
| GSE38129 | KCNK15 | 60598 | 220540_at | -0.0718 | 0.2467 | |
| GSE45670 | KCNK15 | 60598 | 1560620_at | 0.0868 | 0.3872 | |
| GSE53622 | KCNK15 | 60598 | 12282 | -0.6547 | 0.0000 | |
| GSE53624 | KCNK15 | 60598 | 12282 | -1.3099 | 0.0000 | |
| GSE63941 | KCNK15 | 60598 | 1560620_at | 0.1057 | 0.6512 | |
| GSE77861 | KCNK15 | 60598 | 1560620_at | -0.0607 | 0.5984 | |
| GSE97050 | KCNK15 | 60598 | A_23_P109026 | -0.0343 | 0.8760 | |
| SRP133303 | KCNK15 | 60598 | RNAseq | -0.0790 | 0.9012 | |
| SRP159526 | KCNK15 | 60598 | RNAseq | 0.5941 | 0.4040 | |
| SRP219564 | KCNK15 | 60598 | RNAseq | 1.1379 | 0.1044 | |
| TCGA | KCNK15 | 60598 | RNAseq | -1.3061 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KCNK15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNK15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNK15 | 60598 | 13 | 1 | 16 | |
| GSE20123 | KCNK15 | 60598 | 13 | 1 | 16 | |
| GSE43470 | KCNK15 | 60598 | 12 | 2 | 29 | |
| GSE46452 | KCNK15 | 60598 | 29 | 0 | 30 | |
| GSE47630 | KCNK15 | 60598 | 24 | 1 | 15 | |
| GSE54993 | KCNK15 | 60598 | 0 | 17 | 53 | |
| GSE54994 | KCNK15 | 60598 | 25 | 0 | 28 | |
| GSE60625 | KCNK15 | 60598 | 0 | 0 | 11 | |
| GSE74703 | KCNK15 | 60598 | 10 | 2 | 24 | |
| GSE74704 | KCNK15 | 60598 | 9 | 0 | 11 | |
| TCGA | KCNK15 | 60598 | 46 | 3 | 47 |
Total number of gains: 181; Total number of losses: 27; Total Number of normals: 280.
Somatic mutations of KCNK15:
Generating mutation plots.
Highly correlated genes for KCNK15:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNK15 | HBM | 0.682584 | 3 | 0 | 3 |
| KCNK15 | OR1J4 | 0.661229 | 3 | 0 | 3 |
| KCNK15 | ARPP21 | 0.655653 | 4 | 0 | 3 |
| KCNK15 | OR3A1 | 0.651568 | 3 | 0 | 3 |
| KCNK15 | TRPM8 | 0.63544 | 3 | 0 | 3 |
| KCNK15 | INSL6 | 0.62984 | 3 | 0 | 3 |
| KCNK15 | SLC22A13 | 0.628444 | 3 | 0 | 3 |
| KCNK15 | TRH | 0.620832 | 5 | 0 | 5 |
| KCNK15 | SMCP | 0.616799 | 3 | 0 | 3 |
| KCNK15 | GRM1 | 0.611449 | 6 | 0 | 4 |
| KCNK15 | CD1B | 0.608435 | 5 | 0 | 5 |
| KCNK15 | CMTM1 | 0.596587 | 3 | 0 | 3 |
| KCNK15 | CABP5 | 0.585308 | 4 | 0 | 3 |
| KCNK15 | SLC39A5 | 0.580297 | 4 | 0 | 3 |
| KCNK15 | TMEM108 | 0.579235 | 3 | 0 | 3 |
| KCNK15 | DNASE2B | 0.573544 | 3 | 0 | 3 |
| KCNK15 | ADAM7 | 0.572596 | 5 | 0 | 4 |
| KCNK15 | SH2D1A | 0.569426 | 4 | 0 | 3 |
| KCNK15 | HYAL1 | 0.567941 | 5 | 0 | 4 |
| KCNK15 | ZNF280A | 0.565512 | 4 | 0 | 3 |
For details and further investigation, click here
