| Full name: IQ motif containing with AAA domain 1 | Alias Symbol: FLJ22527|DRC11 | ||
| Type: protein-coding gene | Cytoband: 2q37.2-q37.3 | ||
| Entrez ID: 79781 | HGNC ID: HGNC:26195 | Ensembl Gene: ENSG00000132321 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IQCA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQCA1 | 79781 | 220274_at | 0.0459 | 0.9056 | |
| GSE20347 | IQCA1 | 79781 | 220274_at | 0.2139 | 0.0807 | |
| GSE23400 | IQCA1 | 79781 | 220274_at | 0.0433 | 0.3396 | |
| GSE26886 | IQCA1 | 79781 | 220274_at | -0.0071 | 0.9645 | |
| GSE29001 | IQCA1 | 79781 | 220274_at | -0.0480 | 0.8080 | |
| GSE38129 | IQCA1 | 79781 | 220274_at | 0.2994 | 0.0218 | |
| GSE45670 | IQCA1 | 79781 | 220274_at | 0.4736 | 0.0958 | |
| GSE53622 | IQCA1 | 79781 | 71989 | 2.0445 | 0.0000 | |
| GSE53624 | IQCA1 | 79781 | 71989 | 1.5151 | 0.0000 | |
| GSE63941 | IQCA1 | 79781 | 220274_at | 0.1720 | 0.5807 | |
| GSE77861 | IQCA1 | 79781 | 220274_at | 0.1287 | 0.3146 | |
| GSE97050 | IQCA1 | 79781 | A_33_P3314794 | 0.8018 | 0.1397 | |
| SRP064894 | IQCA1 | 79781 | RNAseq | 2.7241 | 0.0000 | |
| SRP133303 | IQCA1 | 79781 | RNAseq | 1.7347 | 0.0002 | |
| SRP159526 | IQCA1 | 79781 | RNAseq | 2.7911 | 0.0000 | |
| SRP219564 | IQCA1 | 79781 | RNAseq | 1.2549 | 0.0936 | |
| TCGA | IQCA1 | 79781 | RNAseq | 1.7755 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by IQCA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IQCA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IQCA1 | 79781 | 1 | 11 | 18 | |
| GSE20123 | IQCA1 | 79781 | 1 | 11 | 18 | |
| GSE43470 | IQCA1 | 79781 | 1 | 9 | 33 | |
| GSE46452 | IQCA1 | 79781 | 0 | 5 | 54 | |
| GSE47630 | IQCA1 | 79781 | 4 | 5 | 31 | |
| GSE54993 | IQCA1 | 79781 | 3 | 2 | 65 | |
| GSE54994 | IQCA1 | 79781 | 8 | 10 | 35 | |
| GSE60625 | IQCA1 | 79781 | 0 | 3 | 8 | |
| GSE74703 | IQCA1 | 79781 | 1 | 7 | 28 | |
| GSE74704 | IQCA1 | 79781 | 1 | 5 | 14 | |
| TCGA | IQCA1 | 79781 | 11 | 29 | 56 |
Total number of gains: 31; Total number of losses: 97; Total Number of normals: 360.
Somatic mutations of IQCA1:
Generating mutation plots.
Highly correlated genes for IQCA1:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQCA1 | TEX13B | 0.697578 | 3 | 0 | 3 |
| IQCA1 | CHST13 | 0.664656 | 3 | 0 | 3 |
| IQCA1 | PRSS53 | 0.662956 | 3 | 0 | 3 |
| IQCA1 | ACAN | 0.656617 | 5 | 0 | 5 |
| IQCA1 | ABCA4 | 0.637894 | 3 | 0 | 3 |
| IQCA1 | CHRD | 0.637663 | 3 | 0 | 3 |
| IQCA1 | VTCN1 | 0.628114 | 3 | 0 | 3 |
| IQCA1 | DAB1 | 0.624824 | 4 | 0 | 3 |
| IQCA1 | ABCC2 | 0.620195 | 4 | 0 | 3 |
| IQCA1 | FNDC9 | 0.61918 | 3 | 0 | 3 |
| IQCA1 | TONSL | 0.618701 | 5 | 0 | 5 |
| IQCA1 | RAI1 | 0.611241 | 4 | 0 | 3 |
| IQCA1 | SLC26A1 | 0.610558 | 3 | 0 | 3 |
| IQCA1 | GRIN1 | 0.609455 | 3 | 0 | 3 |
| IQCA1 | GSTA3 | 0.608655 | 3 | 0 | 3 |
| IQCA1 | ANKRD33B | 0.605393 | 3 | 0 | 3 |
| IQCA1 | DSCAM | 0.60349 | 3 | 0 | 3 |
| IQCA1 | SPEF1 | 0.603219 | 3 | 0 | 3 |
| IQCA1 | HRH2 | 0.601737 | 4 | 0 | 3 |
| IQCA1 | SALL4 | 0.597759 | 4 | 0 | 3 |
For details and further investigation, click here
