| Full name: glutathione S-transferase alpha 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p12.2 | ||
| Entrez ID: 2940 | HGNC ID: HGNC:4628 | Ensembl Gene: ENSG00000174156 | OMIM ID: 605449 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTA3 | 2940 | 222102_at | -0.0450 | 0.9243 | |
| GSE20347 | GSTA3 | 2940 | 222102_at | 0.2681 | 0.0796 | |
| GSE23400 | GSTA3 | 2940 | 222102_at | -0.0364 | 0.4481 | |
| GSE26886 | GSTA3 | 2940 | 222102_at | 0.1500 | 0.2658 | |
| GSE29001 | GSTA3 | 2940 | 222102_at | -0.0267 | 0.9076 | |
| GSE38129 | GSTA3 | 2940 | 222102_at | 0.1199 | 0.4634 | |
| GSE45670 | GSTA3 | 2940 | 222102_at | 0.2039 | 0.2293 | |
| GSE53622 | GSTA3 | 2940 | 1115 | 0.4088 | 0.0072 | |
| GSE53624 | GSTA3 | 2940 | 1115 | 0.3931 | 0.0084 | |
| GSE63941 | GSTA3 | 2940 | 222102_at | 0.0123 | 0.9665 | |
| GSE77861 | GSTA3 | 2940 | 222102_at | 0.3469 | 0.4375 | |
| GSE97050 | GSTA3 | 2940 | A_33_P3257891 | 0.1304 | 0.5287 | |
| TCGA | GSTA3 | 2940 | RNAseq | -3.1451 | 0.0233 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GSTA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTA3 | 2940 | 7 | 2 | 21 | |
| GSE20123 | GSTA3 | 2940 | 7 | 2 | 21 | |
| GSE43470 | GSTA3 | 2940 | 5 | 0 | 38 | |
| GSE46452 | GSTA3 | 2940 | 2 | 10 | 47 | |
| GSE47630 | GSTA3 | 2940 | 7 | 5 | 28 | |
| GSE54993 | GSTA3 | 2940 | 3 | 1 | 66 | |
| GSE54994 | GSTA3 | 2940 | 8 | 4 | 41 | |
| GSE60625 | GSTA3 | 2940 | 0 | 3 | 8 | |
| GSE74703 | GSTA3 | 2940 | 5 | 0 | 31 | |
| GSE74704 | GSTA3 | 2940 | 3 | 1 | 16 | |
| TCGA | GSTA3 | 2940 | 22 | 11 | 63 |
Total number of gains: 69; Total number of losses: 39; Total Number of normals: 380.
Somatic mutations of GSTA3:
Generating mutation plots.
Highly correlated genes for GSTA3:
Showing top 20/236 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTA3 | CREBL2 | 0.716625 | 3 | 0 | 3 |
| GSTA3 | LOXL4 | 0.695676 | 3 | 0 | 3 |
| GSTA3 | TRPM6 | 0.685081 | 4 | 0 | 4 |
| GSTA3 | CD38 | 0.683508 | 3 | 0 | 3 |
| GSTA3 | PDE4D | 0.676987 | 3 | 0 | 3 |
| GSTA3 | BTN1A1 | 0.671593 | 4 | 0 | 3 |
| GSTA3 | NMNAT2 | 0.6701 | 4 | 0 | 4 |
| GSTA3 | MMP7 | 0.666937 | 3 | 0 | 3 |
| GSTA3 | IKZF3 | 0.663175 | 5 | 0 | 4 |
| GSTA3 | CHML | 0.660559 | 4 | 0 | 3 |
| GSTA3 | CCL11 | 0.657268 | 3 | 0 | 3 |
| GSTA3 | HTR7 | 0.656918 | 3 | 0 | 3 |
| GSTA3 | CD79B | 0.651736 | 3 | 0 | 3 |
| GSTA3 | KLRG1 | 0.650189 | 4 | 0 | 4 |
| GSTA3 | GABRA3 | 0.649632 | 3 | 0 | 3 |
| GSTA3 | ERCC4 | 0.649411 | 3 | 0 | 3 |
| GSTA3 | DYRK4 | 0.645777 | 3 | 0 | 3 |
| GSTA3 | SEMA6A | 0.644894 | 3 | 0 | 3 |
| GSTA3 | NAALADL1 | 0.641138 | 3 | 0 | 3 |
| GSTA3 | SYN1 | 0.638805 | 5 | 0 | 4 |
For details and further investigation, click here
