| Full name: M-phase specific PLK1 interacting protein | Alias Symbol: ORF20|TTDN1 | ||
| Type: protein-coding gene | Cytoband: 7p14.1 | ||
| Entrez ID: 136647 | HGNC ID: HGNC:16002 | Ensembl Gene: ENSG00000168303 | OMIM ID: 609188 |
Expression of MPLKIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPLKIP | 136647 | 225419_at | 0.6877 | 0.1299 | |
| GSE26886 | MPLKIP | 136647 | 225419_at | 1.3288 | 0.0000 | |
| GSE45670 | MPLKIP | 136647 | 225419_at | 0.4522 | 0.0138 | |
| GSE53622 | MPLKIP | 136647 | 6428 | 0.8773 | 0.0000 | |
| GSE53624 | MPLKIP | 136647 | 6428 | 0.9246 | 0.0000 | |
| GSE63941 | MPLKIP | 136647 | 225419_at | 1.3965 | 0.0019 | |
| GSE77861 | MPLKIP | 136647 | 225419_at | 0.5164 | 0.0373 | |
| SRP007169 | MPLKIP | 136647 | RNAseq | 0.0532 | 0.8784 | |
| SRP008496 | MPLKIP | 136647 | RNAseq | 0.5494 | 0.0390 | |
| SRP064894 | MPLKIP | 136647 | RNAseq | 0.5732 | 0.0026 | |
| SRP133303 | MPLKIP | 136647 | RNAseq | 0.4016 | 0.0036 | |
| SRP159526 | MPLKIP | 136647 | RNAseq | 0.6015 | 0.0002 | |
| SRP193095 | MPLKIP | 136647 | RNAseq | 0.2027 | 0.0633 | |
| SRP219564 | MPLKIP | 136647 | RNAseq | 0.3391 | 0.2646 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MPLKIP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MPLKIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPLKIP | 136647 | 15 | 0 | 15 | |
| GSE20123 | MPLKIP | 136647 | 14 | 0 | 16 | |
| GSE43470 | MPLKIP | 136647 | 4 | 0 | 39 | |
| GSE46452 | MPLKIP | 136647 | 11 | 1 | 47 | |
| GSE47630 | MPLKIP | 136647 | 8 | 1 | 31 | |
| GSE54993 | MPLKIP | 136647 | 0 | 7 | 63 | |
| GSE54994 | MPLKIP | 136647 | 17 | 3 | 33 | |
| GSE60625 | MPLKIP | 136647 | 0 | 0 | 11 | |
| GSE74703 | MPLKIP | 136647 | 4 | 0 | 32 | |
| GSE74704 | MPLKIP | 136647 | 8 | 0 | 12 | |
| TCGA | MPLKIP | 136647 | 52 | 7 | 37 |
Total number of gains: 133; Total number of losses: 19; Total Number of normals: 336.
Somatic mutations of MPLKIP:
Generating mutation plots.
Highly correlated genes for MPLKIP:
Showing top 20/1353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPLKIP | PLEKHG4B | 0.781547 | 3 | 0 | 3 |
| MPLKIP | CBX3 | 0.776517 | 6 | 0 | 6 |
| MPLKIP | CCDC86 | 0.755799 | 4 | 0 | 4 |
| MPLKIP | MRPS17 | 0.745778 | 5 | 0 | 4 |
| MPLKIP | LSM5 | 0.743661 | 7 | 0 | 7 |
| MPLKIP | MTERF3 | 0.737344 | 4 | 0 | 4 |
| MPLKIP | LRRC8D | 0.732252 | 6 | 0 | 6 |
| MPLKIP | ACOT13 | 0.729075 | 4 | 0 | 4 |
| MPLKIP | LAPTM4B | 0.728295 | 7 | 0 | 7 |
| MPLKIP | RNPS1 | 0.728185 | 4 | 0 | 4 |
| MPLKIP | RPA3 | 0.727205 | 7 | 0 | 6 |
| MPLKIP | HOXD11 | 0.723915 | 6 | 0 | 5 |
| MPLKIP | LPCAT1 | 0.720354 | 6 | 0 | 6 |
| MPLKIP | NUDT1 | 0.718417 | 6 | 0 | 6 |
| MPLKIP | NEIL3 | 0.718344 | 3 | 0 | 3 |
| MPLKIP | POLR2G | 0.717793 | 4 | 0 | 4 |
| MPLKIP | CDH3 | 0.716634 | 5 | 0 | 5 |
| MPLKIP | ADAM17 | 0.71655 | 6 | 0 | 6 |
| MPLKIP | MRGBP | 0.716312 | 6 | 0 | 5 |
| MPLKIP | PSMD14 | 0.71533 | 6 | 0 | 6 |
For details and further investigation, click here
