| Full name: CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated | Alias Symbol: DKFZP586I1023|H_NH0577018.2|MGC19819 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 221960 | HGNC ID: HGNC:21717 | Ensembl Gene: ENSG00000146574 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CCZ1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCZ1B | 221960 | 215024_at | -0.3803 | 0.6176 | |
| GSE20347 | CCZ1B | 221960 | 215024_at | 0.0577 | 0.7913 | |
| GSE23400 | CCZ1B | 221960 | 215024_at | 0.0067 | 0.9338 | |
| GSE26886 | CCZ1B | 221960 | 215024_at | -0.3353 | 0.0549 | |
| GSE29001 | CCZ1B | 221960 | 215024_at | 0.2395 | 0.2942 | |
| GSE38129 | CCZ1B | 221960 | 215024_at | 0.1084 | 0.6844 | |
| GSE45670 | CCZ1B | 221960 | 215024_at | 0.2345 | 0.2144 | |
| GSE63941 | CCZ1B | 221960 | 215024_at | 0.5637 | 0.2389 | |
| GSE77861 | CCZ1B | 221960 | 215024_at | 0.2504 | 0.2642 | |
| SRP007169 | CCZ1B | 221960 | RNAseq | -0.3796 | 0.2894 | |
| SRP008496 | CCZ1B | 221960 | RNAseq | -0.0918 | 0.7260 | |
| SRP064894 | CCZ1B | 221960 | RNAseq | 0.0168 | 0.9479 | |
| SRP133303 | CCZ1B | 221960 | RNAseq | 0.4289 | 0.0660 | |
| SRP159526 | CCZ1B | 221960 | RNAseq | 0.0041 | 0.9821 | |
| SRP193095 | CCZ1B | 221960 | RNAseq | -0.3922 | 0.0239 | |
| SRP219564 | CCZ1B | 221960 | RNAseq | -0.1198 | 0.8143 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of CCZ1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCZ1B | 221960 | 14 | 1 | 15 | |
| GSE20123 | CCZ1B | 221960 | 14 | 1 | 15 | |
| GSE43470 | CCZ1B | 221960 | 7 | 1 | 35 | |
| GSE46452 | CCZ1B | 221960 | 13 | 1 | 45 | |
| GSE47630 | CCZ1B | 221960 | 9 | 1 | 30 | |
| GSE54993 | CCZ1B | 221960 | 0 | 6 | 64 | |
| GSE54994 | CCZ1B | 221960 | 20 | 1 | 32 | |
| GSE60625 | CCZ1B | 221960 | 0 | 0 | 11 | |
| GSE74703 | CCZ1B | 221960 | 7 | 0 | 29 | |
| GSE74704 | CCZ1B | 221960 | 9 | 0 | 11 | |
| TCGA | CCZ1B | 221960 | 56 | 4 | 36 |
Total number of gains: 149; Total number of losses: 16; Total Number of normals: 323.
Somatic mutations of CCZ1B:
Generating mutation plots.
Highly correlated genes for CCZ1B:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCZ1B | VEZT | 0.723504 | 4 | 0 | 4 |
| CCZ1B | EBLN2 | 0.657916 | 5 | 0 | 4 |
| CCZ1B | MDM4 | 0.656023 | 3 | 0 | 3 |
| CCZ1B | PSMD6-AS2 | 0.65577 | 3 | 0 | 3 |
| CCZ1B | DCLRE1C | 0.65206 | 4 | 0 | 3 |
| CCZ1B | ITFG2 | 0.646907 | 4 | 0 | 4 |
| CCZ1B | ATM | 0.613635 | 3 | 0 | 3 |
| CCZ1B | INTS6 | 0.605191 | 3 | 0 | 3 |
| CCZ1B | ENOSF1 | 0.60032 | 4 | 0 | 3 |
| CCZ1B | FNBP4 | 0.596091 | 3 | 0 | 3 |
| CCZ1B | HAUS2 | 0.594005 | 7 | 0 | 5 |
| CCZ1B | POLR1B | 0.593995 | 4 | 0 | 3 |
| CCZ1B | PABPN1 | 0.590901 | 5 | 0 | 4 |
| CCZ1B | RAB14 | 0.589821 | 4 | 0 | 3 |
| CCZ1B | CTBP2 | 0.588747 | 3 | 0 | 3 |
| CCZ1B | GPATCH8 | 0.588497 | 4 | 0 | 3 |
| CCZ1B | DBT | 0.585501 | 7 | 0 | 6 |
| CCZ1B | SNORA21 | 0.583054 | 6 | 0 | 3 |
| CCZ1B | RUSC1-AS1 | 0.580838 | 4 | 0 | 3 |
| CCZ1B | AKAP13 | 0.58052 | 5 | 0 | 4 |
For details and further investigation, click here
