| Full name: Josephin domain containing 1 | Alias Symbol: KIAA0063 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 9929 | HGNC ID: HGNC:28953 | Ensembl Gene: ENSG00000100221 | OMIM ID: 615323 |
| Drug and gene relationship at DGIdb | |||
Expression of JOSD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JOSD1 | 9929 | 201751_at | 0.4022 | 0.3952 | |
| GSE20347 | JOSD1 | 9929 | 201751_at | 0.6595 | 0.0001 | |
| GSE23400 | JOSD1 | 9929 | 201751_at | 0.4976 | 0.0000 | |
| GSE26886 | JOSD1 | 9929 | 201751_at | 0.6299 | 0.0006 | |
| GSE29001 | JOSD1 | 9929 | 201751_at | 0.5191 | 0.0643 | |
| GSE38129 | JOSD1 | 9929 | 201751_at | 0.6331 | 0.0000 | |
| GSE45670 | JOSD1 | 9929 | 201751_at | 0.4360 | 0.0571 | |
| GSE53622 | JOSD1 | 9929 | 39670 | 0.7702 | 0.0000 | |
| GSE53624 | JOSD1 | 9929 | 39670 | 0.8180 | 0.0000 | |
| GSE63941 | JOSD1 | 9929 | 201751_at | 0.3863 | 0.2460 | |
| GSE77861 | JOSD1 | 9929 | 201751_at | 1.1548 | 0.0048 | |
| GSE97050 | JOSD1 | 9929 | A_24_P271527 | 0.2974 | 0.2084 | |
| SRP007169 | JOSD1 | 9929 | RNAseq | 1.2303 | 0.0002 | |
| SRP008496 | JOSD1 | 9929 | RNAseq | 1.0686 | 0.0000 | |
| SRP064894 | JOSD1 | 9929 | RNAseq | 0.7245 | 0.0000 | |
| SRP133303 | JOSD1 | 9929 | RNAseq | 0.7693 | 0.0000 | |
| SRP159526 | JOSD1 | 9929 | RNAseq | 0.8791 | 0.0000 | |
| SRP193095 | JOSD1 | 9929 | RNAseq | 0.6401 | 0.0001 | |
| SRP219564 | JOSD1 | 9929 | RNAseq | 0.6344 | 0.1485 | |
| TCGA | JOSD1 | 9929 | RNAseq | 0.1362 | 0.0036 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by JOSD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JOSD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JOSD1 | 9929 | 6 | 5 | 19 | |
| GSE20123 | JOSD1 | 9929 | 6 | 4 | 20 | |
| GSE43470 | JOSD1 | 9929 | 5 | 5 | 33 | |
| GSE46452 | JOSD1 | 9929 | 32 | 2 | 25 | |
| GSE47630 | JOSD1 | 9929 | 9 | 4 | 27 | |
| GSE54993 | JOSD1 | 9929 | 3 | 6 | 61 | |
| GSE54994 | JOSD1 | 9929 | 9 | 7 | 37 | |
| GSE60625 | JOSD1 | 9929 | 5 | 0 | 6 | |
| GSE74703 | JOSD1 | 9929 | 5 | 4 | 27 | |
| GSE74704 | JOSD1 | 9929 | 3 | 2 | 15 | |
| TCGA | JOSD1 | 9929 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of JOSD1:
Generating mutation plots.
Highly correlated genes for JOSD1:
Showing top 20/1769 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JOSD1 | ADSL | 0.742618 | 13 | 0 | 13 |
| JOSD1 | ALPK2 | 0.733451 | 3 | 0 | 3 |
| JOSD1 | YBX1 | 0.723431 | 5 | 0 | 5 |
| JOSD1 | MORC2 | 0.719051 | 9 | 0 | 9 |
| JOSD1 | PFDN2 | 0.718728 | 11 | 0 | 10 |
| JOSD1 | SUPT16H | 0.717593 | 9 | 0 | 9 |
| JOSD1 | WDR54 | 0.717027 | 7 | 0 | 6 |
| JOSD1 | SLC16A1 | 0.713422 | 9 | 0 | 8 |
| JOSD1 | RUVBL1 | 0.708255 | 10 | 0 | 10 |
| JOSD1 | USP39 | 0.707928 | 10 | 0 | 10 |
| JOSD1 | TMEM38B | 0.705876 | 9 | 0 | 8 |
| JOSD1 | AATF | 0.701739 | 11 | 0 | 11 |
| JOSD1 | FANCB | 0.701421 | 4 | 0 | 4 |
| JOSD1 | TTL | 0.700661 | 7 | 0 | 7 |
| JOSD1 | PYCR2 | 0.699852 | 3 | 0 | 3 |
| JOSD1 | MMS22L | 0.69983 | 3 | 0 | 3 |
| JOSD1 | SLC25A17 | 0.69943 | 10 | 0 | 9 |
| JOSD1 | SNRPE | 0.697259 | 9 | 0 | 9 |
| JOSD1 | TMEM184B | 0.695372 | 11 | 0 | 10 |
| JOSD1 | PIKFYVE | 0.695306 | 3 | 0 | 3 |
For details and further investigation, click here
