| Full name: ubiquitin specific peptidase 39 | Alias Symbol: SAD1|CGI-21|SNRNP65 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 10713 | HGNC ID: HGNC:20071 | Ensembl Gene: ENSG00000168883 | OMIM ID: 611594 |
| Drug and gene relationship at DGIdb | |||
Expression of USP39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP39 | 10713 | 217829_s_at | 0.6610 | 0.0703 | |
| GSE20347 | USP39 | 10713 | 217829_s_at | 0.5964 | 0.0001 | |
| GSE23400 | USP39 | 10713 | 217829_s_at | 0.5810 | 0.0000 | |
| GSE26886 | USP39 | 10713 | 217829_s_at | 0.1616 | 0.4545 | |
| GSE29001 | USP39 | 10713 | 217829_s_at | 0.5049 | 0.0235 | |
| GSE38129 | USP39 | 10713 | 217829_s_at | 0.6352 | 0.0000 | |
| GSE45670 | USP39 | 10713 | 217829_s_at | 0.4364 | 0.0273 | |
| GSE53622 | USP39 | 10713 | 101474 | 0.5871 | 0.0000 | |
| GSE53624 | USP39 | 10713 | 101474 | 0.7061 | 0.0000 | |
| GSE63941 | USP39 | 10713 | 217829_s_at | 0.4829 | 0.2660 | |
| GSE77861 | USP39 | 10713 | 217829_s_at | 0.6832 | 0.0019 | |
| GSE97050 | USP39 | 10713 | A_33_P3399840 | 0.3691 | 0.1984 | |
| SRP007169 | USP39 | 10713 | RNAseq | 1.0182 | 0.0192 | |
| SRP008496 | USP39 | 10713 | RNAseq | 1.1376 | 0.0000 | |
| SRP064894 | USP39 | 10713 | RNAseq | 0.4674 | 0.0002 | |
| SRP133303 | USP39 | 10713 | RNAseq | 0.7613 | 0.0000 | |
| SRP159526 | USP39 | 10713 | RNAseq | 1.1334 | 0.0000 | |
| SRP193095 | USP39 | 10713 | RNAseq | 0.4874 | 0.0000 | |
| SRP219564 | USP39 | 10713 | RNAseq | 0.2785 | 0.2875 | |
| TCGA | USP39 | 10713 | RNAseq | 0.1821 | 0.0003 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by USP39 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP39 | 10713 | 9 | 2 | 19 | |
| GSE20123 | USP39 | 10713 | 9 | 2 | 19 | |
| GSE43470 | USP39 | 10713 | 6 | 2 | 35 | |
| GSE46452 | USP39 | 10713 | 2 | 3 | 54 | |
| GSE47630 | USP39 | 10713 | 7 | 0 | 33 | |
| GSE54993 | USP39 | 10713 | 0 | 6 | 64 | |
| GSE54994 | USP39 | 10713 | 10 | 0 | 43 | |
| GSE60625 | USP39 | 10713 | 0 | 3 | 8 | |
| GSE74703 | USP39 | 10713 | 5 | 1 | 30 | |
| GSE74704 | USP39 | 10713 | 7 | 0 | 13 | |
| TCGA | USP39 | 10713 | 35 | 4 | 57 |
Total number of gains: 90; Total number of losses: 23; Total Number of normals: 375.
Somatic mutations of USP39:
Generating mutation plots.
Highly correlated genes for USP39:
Showing top 20/1944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP39 | CDCA2 | 0.791844 | 4 | 0 | 4 |
| USP39 | KNSTRN | 0.776693 | 5 | 0 | 5 |
| USP39 | MRPL47 | 0.774414 | 6 | 0 | 6 |
| USP39 | CDCA3 | 0.763186 | 10 | 0 | 10 |
| USP39 | UCK2 | 0.757154 | 3 | 0 | 3 |
| USP39 | TTL | 0.756119 | 6 | 0 | 6 |
| USP39 | MMS22L | 0.756069 | 3 | 0 | 3 |
| USP39 | MCM6 | 0.75317 | 11 | 0 | 10 |
| USP39 | DGUOK | 0.748196 | 12 | 0 | 11 |
| USP39 | ITGB8 | 0.746183 | 3 | 0 | 3 |
| USP39 | ZNF707 | 0.744283 | 3 | 0 | 3 |
| USP39 | MSH6 | 0.740239 | 13 | 0 | 12 |
| USP39 | RNF26 | 0.739437 | 4 | 0 | 3 |
| USP39 | METTL23 | 0.739015 | 6 | 0 | 6 |
| USP39 | RPL39L | 0.736234 | 11 | 0 | 10 |
| USP39 | BOLA3 | 0.735081 | 6 | 0 | 6 |
| USP39 | SMARCE1 | 0.734118 | 4 | 0 | 3 |
| USP39 | HSPD1 | 0.730853 | 10 | 0 | 10 |
| USP39 | MRM1 | 0.728969 | 3 | 0 | 3 |
| USP39 | A4GALT | 0.728729 | 3 | 0 | 3 |
For details and further investigation, click here
