| Full name: vesicle transport through interaction with t-SNAREs 1A | Alias Symbol: MVti1|Vti1a|Vti1-rp2 | ||
| Type: protein-coding gene | Cytoband: 10q25.2 | ||
| Entrez ID: 143187 | HGNC ID: HGNC:17792 | Ensembl Gene: ENSG00000151532 | OMIM ID: 614316 |
| Drug and gene relationship at DGIdb | |||
Expression of VTI1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VTI1A | 143187 | 235923_at | -0.3974 | 0.3815 | |
| GSE26886 | VTI1A | 143187 | 235034_at | -0.8064 | 0.0000 | |
| GSE45670 | VTI1A | 143187 | 235923_at | -0.1201 | 0.4440 | |
| GSE53622 | VTI1A | 143187 | 22522 | -0.5526 | 0.0000 | |
| GSE53624 | VTI1A | 143187 | 22522 | -0.6851 | 0.0000 | |
| GSE63941 | VTI1A | 143187 | 235923_at | 0.5669 | 0.1624 | |
| GSE77861 | VTI1A | 143187 | 235034_at | -0.1245 | 0.3681 | |
| GSE97050 | VTI1A | 143187 | A_23_P10785 | 0.0996 | 0.6747 | |
| SRP007169 | VTI1A | 143187 | RNAseq | -1.0626 | 0.0226 | |
| SRP008496 | VTI1A | 143187 | RNAseq | -0.6728 | 0.0110 | |
| SRP064894 | VTI1A | 143187 | RNAseq | -0.8753 | 0.0000 | |
| SRP133303 | VTI1A | 143187 | RNAseq | -0.0207 | 0.8028 | |
| SRP159526 | VTI1A | 143187 | RNAseq | -0.3465 | 0.0431 | |
| SRP193095 | VTI1A | 143187 | RNAseq | -0.1176 | 0.3481 | |
| SRP219564 | VTI1A | 143187 | RNAseq | -0.7068 | 0.0785 | |
| TCGA | VTI1A | 143187 | RNAseq | -0.0586 | 0.2784 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VTI1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VTI1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VTI1A | 143187 | 1 | 9 | 20 | |
| GSE20123 | VTI1A | 143187 | 1 | 8 | 21 | |
| GSE43470 | VTI1A | 143187 | 0 | 9 | 34 | |
| GSE46452 | VTI1A | 143187 | 0 | 11 | 48 | |
| GSE47630 | VTI1A | 143187 | 2 | 14 | 24 | |
| GSE54993 | VTI1A | 143187 | 8 | 0 | 62 | |
| GSE54994 | VTI1A | 143187 | 1 | 10 | 42 | |
| GSE60625 | VTI1A | 143187 | 0 | 0 | 11 | |
| GSE74703 | VTI1A | 143187 | 0 | 6 | 30 | |
| GSE74704 | VTI1A | 143187 | 1 | 4 | 15 | |
| TCGA | VTI1A | 143187 | 4 | 30 | 62 |
Total number of gains: 18; Total number of losses: 101; Total Number of normals: 369.
Somatic mutations of VTI1A:
Generating mutation plots.
Highly correlated genes for VTI1A:
Showing top 20/812 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VTI1A | SLC10A7 | 0.699287 | 3 | 0 | 3 |
| VTI1A | ORMDL2 | 0.696856 | 6 | 0 | 6 |
| VTI1A | STX17 | 0.692896 | 4 | 0 | 4 |
| VTI1A | UNC5B | 0.688059 | 3 | 0 | 3 |
| VTI1A | PRSS8 | 0.678114 | 3 | 0 | 3 |
| VTI1A | KCNJ14 | 0.677798 | 3 | 0 | 3 |
| VTI1A | TTC39B | 0.675542 | 3 | 0 | 3 |
| VTI1A | PRELID1 | 0.672744 | 3 | 0 | 3 |
| VTI1A | STXBP5 | 0.672196 | 5 | 0 | 5 |
| VTI1A | RBPJL | 0.667964 | 3 | 0 | 3 |
| VTI1A | HIPK1 | 0.663396 | 4 | 0 | 4 |
| VTI1A | C18orf25 | 0.661096 | 5 | 0 | 4 |
| VTI1A | ARL2BP | 0.659908 | 3 | 0 | 3 |
| VTI1A | PDCD6IP | 0.659751 | 5 | 0 | 4 |
| VTI1A | NAMPT | 0.65668 | 3 | 0 | 3 |
| VTI1A | ARPC2 | 0.655767 | 6 | 0 | 6 |
| VTI1A | TMOD3 | 0.6522 | 5 | 0 | 5 |
| VTI1A | ANKRD44 | 0.650368 | 3 | 0 | 3 |
| VTI1A | CNPPD1 | 0.649922 | 5 | 0 | 4 |
| VTI1A | KDM5C | 0.649247 | 3 | 0 | 3 |
For details and further investigation, click here
