| Full name: epsin 3 | Alias Symbol: FLJ20778|MGC129899 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 55040 | HGNC ID: HGNC:18235 | Ensembl Gene: ENSG00000049283 | OMIM ID: 607264 |
| Drug and gene relationship at DGIdb | |||
Expression of EPN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPN3 | 55040 | 223895_s_at | -1.1467 | 0.1852 | |
| GSE20347 | EPN3 | 55040 | 220318_at | -1.0674 | 0.0000 | |
| GSE23400 | EPN3 | 55040 | 220318_at | -0.4458 | 0.0000 | |
| GSE26886 | EPN3 | 55040 | 223895_s_at | -0.2667 | 0.3473 | |
| GSE29001 | EPN3 | 55040 | 220318_at | -0.9580 | 0.0017 | |
| GSE38129 | EPN3 | 55040 | 220318_at | -0.6437 | 0.0164 | |
| GSE45670 | EPN3 | 55040 | 223895_s_at | -0.2643 | 0.3193 | |
| GSE53622 | EPN3 | 55040 | 120058 | -1.0364 | 0.0017 | |
| GSE53624 | EPN3 | 55040 | 120058 | -1.6892 | 0.0000 | |
| GSE63941 | EPN3 | 55040 | 223895_s_at | 3.1229 | 0.0059 | |
| GSE77861 | EPN3 | 55040 | 223895_s_at | -0.7709 | 0.1258 | |
| GSE97050 | EPN3 | 55040 | A_23_P130027 | -0.3688 | 0.5507 | |
| SRP007169 | EPN3 | 55040 | RNAseq | -2.6488 | 0.0000 | |
| SRP008496 | EPN3 | 55040 | RNAseq | -2.6371 | 0.0000 | |
| SRP064894 | EPN3 | 55040 | RNAseq | -1.4641 | 0.0001 | |
| SRP133303 | EPN3 | 55040 | RNAseq | -1.6931 | 0.0000 | |
| SRP159526 | EPN3 | 55040 | RNAseq | -1.9755 | 0.0020 | |
| SRP193095 | EPN3 | 55040 | RNAseq | -1.3878 | 0.0000 | |
| SRP219564 | EPN3 | 55040 | RNAseq | -1.5696 | 0.0875 | |
| TCGA | EPN3 | 55040 | RNAseq | -0.3046 | 0.1115 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by EPN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPN3 | 55040 | 5 | 2 | 23 | |
| GSE20123 | EPN3 | 55040 | 5 | 2 | 23 | |
| GSE43470 | EPN3 | 55040 | 3 | 2 | 38 | |
| GSE46452 | EPN3 | 55040 | 32 | 0 | 27 | |
| GSE47630 | EPN3 | 55040 | 9 | 0 | 31 | |
| GSE54993 | EPN3 | 55040 | 2 | 4 | 64 | |
| GSE54994 | EPN3 | 55040 | 9 | 6 | 38 | |
| GSE60625 | EPN3 | 55040 | 4 | 0 | 7 | |
| GSE74703 | EPN3 | 55040 | 3 | 2 | 31 | |
| GSE74704 | EPN3 | 55040 | 4 | 1 | 15 | |
| TCGA | EPN3 | 55040 | 26 | 8 | 62 |
Total number of gains: 102; Total number of losses: 27; Total Number of normals: 359.
Somatic mutations of EPN3:
Generating mutation plots.
Highly correlated genes for EPN3:
Showing top 20/1341 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPN3 | KIAA1522 | 0.830648 | 3 | 0 | 3 |
| EPN3 | EPHA1 | 0.79416 | 10 | 0 | 10 |
| EPN3 | RAB25 | 0.786782 | 11 | 0 | 11 |
| EPN3 | NIPAL1 | 0.783802 | 3 | 0 | 3 |
| EPN3 | TECR | 0.777869 | 10 | 0 | 10 |
| EPN3 | TOM1 | 0.76433 | 10 | 0 | 10 |
| EPN3 | MPZL3 | 0.75996 | 7 | 0 | 7 |
| EPN3 | SLAIN2 | 0.750431 | 3 | 0 | 3 |
| EPN3 | NUAK2 | 0.749767 | 3 | 0 | 3 |
| EPN3 | CKMT1A | 0.747055 | 3 | 0 | 3 |
| EPN3 | TM7SF2 | 0.740403 | 11 | 0 | 11 |
| EPN3 | PLEKHM1 | 0.738825 | 10 | 0 | 10 |
| EPN3 | EVPL | 0.733631 | 12 | 0 | 11 |
| EPN3 | EXPH5 | 0.73243 | 10 | 0 | 10 |
| EPN3 | EPS8L2 | 0.732104 | 10 | 0 | 9 |
| EPN3 | TVP23B | 0.725886 | 3 | 0 | 3 |
| EPN3 | SLC9A3R1 | 0.716903 | 11 | 0 | 11 |
| EPN3 | CRB3 | 0.716725 | 8 | 0 | 7 |
| EPN3 | ASPG | 0.71459 | 6 | 0 | 6 |
| EPN3 | TOLLIP | 0.712245 | 9 | 0 | 8 |
For details and further investigation, click here
