| Full name: kinesin family member 1C | Alias Symbol: SPAX2|SPG58 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 10749 | HGNC ID: HGNC:6317 | Ensembl Gene: ENSG00000129250 | OMIM ID: 603060 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF1C | 10749 | 238477_at | -0.5749 | 0.1478 | |
| GSE20347 | KIF1C | 10749 | 209244_s_at | -0.7518 | 0.0000 | |
| GSE23400 | KIF1C | 10749 | 209244_s_at | -0.4525 | 0.0000 | |
| GSE26886 | KIF1C | 10749 | 238477_at | -1.8565 | 0.0000 | |
| GSE29001 | KIF1C | 10749 | 209244_s_at | -0.6521 | 0.0319 | |
| GSE38129 | KIF1C | 10749 | 209244_s_at | -0.6453 | 0.0000 | |
| GSE45670 | KIF1C | 10749 | 209244_s_at | -0.2870 | 0.0332 | |
| GSE53622 | KIF1C | 10749 | 58137 | -1.2819 | 0.0000 | |
| GSE53624 | KIF1C | 10749 | 58137 | -1.2132 | 0.0000 | |
| GSE63941 | KIF1C | 10749 | 238477_at | -0.9480 | 0.0781 | |
| GSE77861 | KIF1C | 10749 | 209244_s_at | -0.3980 | 0.0036 | |
| GSE97050 | KIF1C | 10749 | A_33_P3230709 | -0.6755 | 0.0992 | |
| SRP007169 | KIF1C | 10749 | RNAseq | -1.3366 | 0.0007 | |
| SRP008496 | KIF1C | 10749 | RNAseq | -1.2601 | 0.0000 | |
| SRP064894 | KIF1C | 10749 | RNAseq | -0.8561 | 0.0000 | |
| SRP133303 | KIF1C | 10749 | RNAseq | -1.1423 | 0.0000 | |
| SRP159526 | KIF1C | 10749 | RNAseq | -1.3653 | 0.0001 | |
| SRP193095 | KIF1C | 10749 | RNAseq | -0.9524 | 0.0000 | |
| SRP219564 | KIF1C | 10749 | RNAseq | -0.9639 | 0.0046 | |
| TCGA | KIF1C | 10749 | RNAseq | -0.3130 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by KIF1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF1C | 10749 | 5 | 2 | 23 | |
| GSE20123 | KIF1C | 10749 | 5 | 3 | 22 | |
| GSE43470 | KIF1C | 10749 | 1 | 6 | 36 | |
| GSE46452 | KIF1C | 10749 | 34 | 1 | 24 | |
| GSE47630 | KIF1C | 10749 | 7 | 1 | 32 | |
| GSE54993 | KIF1C | 10749 | 4 | 3 | 63 | |
| GSE54994 | KIF1C | 10749 | 5 | 9 | 39 | |
| GSE60625 | KIF1C | 10749 | 4 | 0 | 7 | |
| GSE74703 | KIF1C | 10749 | 1 | 3 | 32 | |
| GSE74704 | KIF1C | 10749 | 3 | 1 | 16 | |
| TCGA | KIF1C | 10749 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of KIF1C:
Generating mutation plots.
Highly correlated genes for KIF1C:
Showing top 20/1576 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF1C | FAM3D | 0.770745 | 6 | 0 | 6 |
| KIF1C | CLEC3B | 0.768494 | 3 | 0 | 3 |
| KIF1C | RAB5B | 0.759579 | 11 | 0 | 10 |
| KIF1C | TPCN1 | 0.755562 | 11 | 0 | 10 |
| KIF1C | SMIM5 | 0.753358 | 6 | 0 | 6 |
| KIF1C | ANO10 | 0.752753 | 10 | 0 | 10 |
| KIF1C | AIF1L | 0.752554 | 6 | 0 | 5 |
| KIF1C | VSIG10L | 0.752301 | 6 | 0 | 5 |
| KIF1C | SNORA68 | 0.750828 | 4 | 0 | 4 |
| KIF1C | CHP1 | 0.749369 | 10 | 0 | 10 |
| KIF1C | CYSRT1 | 0.746848 | 6 | 0 | 6 |
| KIF1C | MGLL | 0.746789 | 12 | 0 | 11 |
| KIF1C | AMOTL2 | 0.74671 | 11 | 0 | 11 |
| KIF1C | PIM1 | 0.744422 | 11 | 0 | 11 |
| KIF1C | ACOX3 | 0.742481 | 10 | 0 | 10 |
| KIF1C | SH3BGRL2 | 0.742004 | 7 | 0 | 7 |
| KIF1C | GBP6 | 0.740107 | 4 | 0 | 4 |
| KIF1C | SHROOM3 | 0.739915 | 7 | 0 | 7 |
| KIF1C | GRTP1-AS1 | 0.739352 | 3 | 0 | 3 |
| KIF1C | SPINK7 | 0.737348 | 6 | 0 | 6 |
For details and further investigation, click here
