| Full name: synaptotagmin 7 | Alias Symbol: IPCA-7|SYT-VII|MGC150517 | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 9066 | HGNC ID: HGNC:11514 | Ensembl Gene: ENSG00000011347 | OMIM ID: 604146 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT7 | 9066 | 226167_at | 0.2450 | 0.3702 | |
| GSE26886 | SYT7 | 9066 | 226167_at | 0.6057 | 0.0016 | |
| GSE45670 | SYT7 | 9066 | 226167_at | 0.1939 | 0.1387 | |
| GSE53622 | SYT7 | 9066 | 71007 | 0.0217 | 0.8426 | |
| GSE53624 | SYT7 | 9066 | 1845 | 0.6420 | 0.0000 | |
| GSE63941 | SYT7 | 9066 | 232025_at | 0.5479 | 0.0434 | |
| GSE77861 | SYT7 | 9066 | 226167_at | 0.2271 | 0.3060 | |
| GSE97050 | SYT7 | 9066 | A_33_P3239185 | 0.4838 | 0.1820 | |
| SRP064894 | SYT7 | 9066 | RNAseq | 0.1985 | 0.5765 | |
| SRP133303 | SYT7 | 9066 | RNAseq | 0.5630 | 0.1286 | |
| SRP159526 | SYT7 | 9066 | RNAseq | 1.2616 | 0.0002 | |
| SRP193095 | SYT7 | 9066 | RNAseq | 1.0747 | 0.0000 | |
| SRP219564 | SYT7 | 9066 | RNAseq | 1.4524 | 0.0178 | |
| TCGA | SYT7 | 9066 | RNAseq | 0.5107 | 0.0009 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SYT7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT7 | 9066 | 4 | 5 | 21 | |
| GSE20123 | SYT7 | 9066 | 4 | 5 | 21 | |
| GSE43470 | SYT7 | 9066 | 2 | 6 | 35 | |
| GSE46452 | SYT7 | 9066 | 8 | 4 | 47 | |
| GSE47630 | SYT7 | 9066 | 3 | 8 | 29 | |
| GSE54993 | SYT7 | 9066 | 3 | 0 | 67 | |
| GSE54994 | SYT7 | 9066 | 5 | 5 | 43 | |
| GSE60625 | SYT7 | 9066 | 0 | 3 | 8 | |
| GSE74703 | SYT7 | 9066 | 2 | 3 | 31 | |
| GSE74704 | SYT7 | 9066 | 3 | 3 | 14 | |
| TCGA | SYT7 | 9066 | 15 | 10 | 71 |
Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.
Somatic mutations of SYT7:
Generating mutation plots.
Highly correlated genes for SYT7:
Showing top 20/412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT7 | TLCD1 | 0.789542 | 3 | 0 | 3 |
| SYT7 | LRP8 | 0.743726 | 3 | 0 | 3 |
| SYT7 | ADORA2B | 0.727215 | 4 | 0 | 4 |
| SYT7 | SLC4A1AP | 0.723271 | 3 | 0 | 3 |
| SYT7 | TRADD | 0.720486 | 3 | 0 | 3 |
| SYT7 | DHCR7 | 0.713694 | 4 | 0 | 3 |
| SYT7 | ATP1B3 | 0.707823 | 3 | 0 | 3 |
| SYT7 | RBM38 | 0.707529 | 3 | 0 | 3 |
| SYT7 | DUSP7 | 0.694539 | 3 | 0 | 3 |
| SYT7 | ABCA12 | 0.687921 | 4 | 0 | 4 |
| SYT7 | TGFB1 | 0.68484 | 4 | 0 | 4 |
| SYT7 | TRMT6 | 0.682782 | 3 | 0 | 3 |
| SYT7 | TTK | 0.678415 | 3 | 0 | 3 |
| SYT7 | MPLKIP | 0.677234 | 3 | 0 | 3 |
| SYT7 | KRT18 | 0.675354 | 3 | 0 | 3 |
| SYT7 | FAM110A | 0.673417 | 4 | 0 | 3 |
| SYT7 | ELOVL7 | 0.673047 | 3 | 0 | 3 |
| SYT7 | CCT6A | 0.672509 | 3 | 0 | 3 |
| SYT7 | TMED9 | 0.672159 | 3 | 0 | 3 |
| SYT7 | BUB1 | 0.671065 | 3 | 0 | 3 |
For details and further investigation, click here
