| Full name: keratin 85 | Alias Symbol: Hb-5 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3891 | HGNC ID: HGNC:6462 | Ensembl Gene: ENSG00000135443 | OMIM ID: 602767 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT85:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT85 | 3891 | 207670_at | 0.0457 | 0.8579 | |
| GSE20347 | KRT85 | 3891 | 207670_at | 0.0290 | 0.6927 | |
| GSE23400 | KRT85 | 3891 | 207670_at | -0.1044 | 0.0030 | |
| GSE26886 | KRT85 | 3891 | 207670_at | 0.1578 | 0.2142 | |
| GSE29001 | KRT85 | 3891 | 207670_at | 0.2314 | 0.3897 | |
| GSE38129 | KRT85 | 3891 | 207670_at | -0.0076 | 0.9239 | |
| GSE45670 | KRT85 | 3891 | 207670_at | 0.0683 | 0.5838 | |
| GSE53622 | KRT85 | 3891 | 7466 | 0.4149 | 0.0009 | |
| GSE53624 | KRT85 | 3891 | 7466 | 0.3268 | 0.0037 | |
| GSE63941 | KRT85 | 3891 | 207670_at | 0.0704 | 0.6814 | |
| GSE77861 | KRT85 | 3891 | 207670_at | -0.0730 | 0.6370 | |
| TCGA | KRT85 | 3891 | RNAseq | 1.3805 | 0.2947 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRT85 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT85:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT85 | 3891 | 8 | 1 | 21 | |
| GSE20123 | KRT85 | 3891 | 8 | 1 | 21 | |
| GSE43470 | KRT85 | 3891 | 3 | 0 | 40 | |
| GSE46452 | KRT85 | 3891 | 7 | 1 | 51 | |
| GSE47630 | KRT85 | 3891 | 10 | 2 | 28 | |
| GSE54993 | KRT85 | 3891 | 0 | 5 | 65 | |
| GSE54994 | KRT85 | 3891 | 4 | 1 | 48 | |
| GSE60625 | KRT85 | 3891 | 0 | 0 | 11 | |
| GSE74703 | KRT85 | 3891 | 3 | 0 | 33 | |
| GSE74704 | KRT85 | 3891 | 5 | 1 | 14 | |
| TCGA | KRT85 | 3891 | 12 | 11 | 73 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of KRT85:
Generating mutation plots.
Highly correlated genes for KRT85:
Showing top 20/270 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT85 | SHC3 | 0.681337 | 3 | 0 | 3 |
| KRT85 | DERL3 | 0.670327 | 4 | 0 | 4 |
| KRT85 | CPA2 | 0.649267 | 3 | 0 | 3 |
| KRT85 | FCGR2C | 0.646215 | 4 | 0 | 4 |
| KRT85 | GAD2 | 0.644231 | 3 | 0 | 3 |
| KRT85 | LINC01085 | 0.631214 | 3 | 0 | 3 |
| KRT85 | SLC34A2 | 0.628375 | 3 | 0 | 3 |
| KRT85 | L3MBTL1 | 0.619019 | 3 | 0 | 3 |
| KRT85 | NDP | 0.613809 | 4 | 0 | 3 |
| KRT85 | ACR | 0.612796 | 4 | 0 | 3 |
| KRT85 | SYT13 | 0.610476 | 3 | 0 | 3 |
| KRT85 | PTPRJ | 0.610277 | 5 | 0 | 4 |
| KRT85 | EPHB2 | 0.609691 | 4 | 0 | 4 |
| KRT85 | CRYBB1 | 0.603419 | 3 | 0 | 3 |
| KRT85 | CA6 | 0.603365 | 4 | 0 | 3 |
| KRT85 | NTNG1 | 0.60047 | 3 | 0 | 3 |
| KRT85 | NPPB | 0.59985 | 7 | 0 | 5 |
| KRT85 | GDF2 | 0.598063 | 3 | 0 | 3 |
| KRT85 | ADAMTS6 | 0.597492 | 4 | 0 | 3 |
| KRT85 | CCR3 | 0.595706 | 6 | 0 | 5 |
For details and further investigation, click here
