| Full name: PR/SET domain 16 | Alias Symbol: MEL1|PFM13|KIAA1675|MGC166915|KMT8F | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 63976 | HGNC ID: HGNC:14000 | Ensembl Gene: ENSG00000142611 | OMIM ID: 605557 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM16 | 63976 | 220928_s_at | 0.0169 | 0.9548 | |
| GSE20347 | PRDM16 | 63976 | 220928_s_at | 0.0265 | 0.7726 | |
| GSE23400 | PRDM16 | 63976 | 220928_s_at | 0.0106 | 0.8009 | |
| GSE26886 | PRDM16 | 63976 | 220928_s_at | 0.2824 | 0.0635 | |
| GSE29001 | PRDM16 | 63976 | 220928_s_at | 0.1643 | 0.4523 | |
| GSE38129 | PRDM16 | 63976 | 220928_s_at | -0.0267 | 0.7362 | |
| GSE45670 | PRDM16 | 63976 | 220928_s_at | 0.0384 | 0.7468 | |
| GSE53622 | PRDM16 | 63976 | 52558 | -0.3673 | 0.0002 | |
| GSE53624 | PRDM16 | 63976 | 52558 | -0.8696 | 0.0000 | |
| GSE63941 | PRDM16 | 63976 | 220928_s_at | 0.1717 | 0.4065 | |
| GSE77861 | PRDM16 | 63976 | 220928_s_at | -0.0741 | 0.5265 | |
| GSE97050 | PRDM16 | 63976 | A_33_P3382309 | -0.1876 | 0.4412 | |
| SRP133303 | PRDM16 | 63976 | RNAseq | -1.2275 | 0.0000 | |
| SRP159526 | PRDM16 | 63976 | RNAseq | 0.4974 | 0.4457 | |
| TCGA | PRDM16 | 63976 | RNAseq | -1.8677 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PRDM16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM16 | 63976 | 4 | 7 | 19 | |
| GSE20123 | PRDM16 | 63976 | 4 | 5 | 21 | |
| GSE43470 | PRDM16 | 63976 | 3 | 5 | 35 | |
| GSE46452 | PRDM16 | 63976 | 7 | 1 | 51 | |
| GSE47630 | PRDM16 | 63976 | 8 | 4 | 28 | |
| GSE54993 | PRDM16 | 63976 | 3 | 2 | 65 | |
| GSE54994 | PRDM16 | 63976 | 14 | 3 | 36 | |
| GSE60625 | PRDM16 | 63976 | 0 | 0 | 11 | |
| GSE74703 | PRDM16 | 63976 | 3 | 3 | 30 | |
| GSE74704 | PRDM16 | 63976 | 4 | 0 | 16 | |
| TCGA | PRDM16 | 63976 | 15 | 20 | 61 |
Total number of gains: 65; Total number of losses: 50; Total Number of normals: 373.
Somatic mutations of PRDM16:
Generating mutation plots.
Highly correlated genes for PRDM16:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM16 | TDGF1 | 0.792708 | 3 | 0 | 3 |
| PRDM16 | SCARA5 | 0.784896 | 3 | 0 | 3 |
| PRDM16 | GDF7 | 0.783539 | 3 | 0 | 3 |
| PRDM16 | KRTAP6-1 | 0.776075 | 3 | 0 | 3 |
| PRDM16 | FXYD2 | 0.772667 | 3 | 0 | 3 |
| PRDM16 | FOXA3 | 0.752453 | 3 | 0 | 3 |
| PRDM16 | DNAJB8 | 0.751208 | 3 | 0 | 3 |
| PRDM16 | MFSD6L | 0.720574 | 3 | 0 | 3 |
| PRDM16 | TTC7A | 0.712774 | 3 | 0 | 3 |
| PRDM16 | YY2 | 0.711295 | 3 | 0 | 3 |
| PRDM16 | SPACA3 | 0.709303 | 3 | 0 | 3 |
| PRDM16 | GPT | 0.708018 | 3 | 0 | 3 |
| PRDM16 | CLCNKA | 0.706635 | 3 | 0 | 3 |
| PRDM16 | HTR3A | 0.706171 | 4 | 0 | 4 |
| PRDM16 | ENTPD8 | 0.701839 | 3 | 0 | 3 |
| PRDM16 | PSPN | 0.698911 | 4 | 0 | 4 |
| PRDM16 | NT5C1A | 0.698712 | 3 | 0 | 3 |
| PRDM16 | SLC22A12 | 0.696462 | 4 | 0 | 3 |
| PRDM16 | BEST4 | 0.69141 | 3 | 0 | 3 |
| PRDM16 | OR4C3 | 0.691031 | 3 | 0 | 3 |
For details and further investigation, click here
