L3MBTL2

 

Full name: L3MBTL histone methyl-lysine binding protein 2 Alias Symbol: H-l(3)mbt-l|DKFZP761I141|dJ756G23.3
Type: protein-coding gene Cytoband: 22q13.2
Entrez ID: 83746 HGNC ID: HGNC:18594 Ensembl Gene: ENSG00000100395 OMIM ID: 611865
Drug and gene relationship at DGIdb

 

Expression of L3MBTL2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 L3MBTL2 83746 223205_s_at 0.0533 0.8528
GSE26886 L3MBTL2 83746 223205_s_at -0.0056 0.9712
GSE45670 L3MBTL2 83746 223205_s_at 0.1763 0.0239
GSE53622 L3MBTL2 83746 4734 0.1190 0.0724
GSE53624 L3MBTL2 83746 4734 0.2332 0.0000
GSE63941 L3MBTL2 83746 223205_s_at 0.3315 0.1626
GSE77861 L3MBTL2 83746 223205_s_at 0.0623 0.6328
GSE97050 L3MBTL2 83746 A_23_P80353 0.2605 0.3058
SRP007169 L3MBTL2 83746 RNAseq 0.7566 0.1795
SRP008496 L3MBTL2 83746 RNAseq 0.2991 0.3909
SRP064894 L3MBTL2 83746 RNAseq 0.5882 0.0008
SRP133303 L3MBTL2 83746 RNAseq 0.0865 0.4959
SRP159526 L3MBTL2 83746 RNAseq 0.2770 0.2355
SRP193095 L3MBTL2 83746 RNAseq 0.2262 0.0108
SRP219564 L3MBTL2 83746 RNAseq 0.3976 0.1322
TCGA L3MBTL2 83746 RNAseq -0.0398 0.4219

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by L3MBTL2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of L3MBTL2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 L3MBTL2 83746 6 5 19
GSE20123 L3MBTL2 83746 6 4 20
GSE43470 L3MBTL2 83746 4 6 33
GSE46452 L3MBTL2 83746 31 2 26
GSE47630 L3MBTL2 83746 9 4 27
GSE54993 L3MBTL2 83746 3 6 61
GSE54994 L3MBTL2 83746 11 8 34
GSE60625 L3MBTL2 83746 5 0 6
GSE74703 L3MBTL2 83746 4 4 28
GSE74704 L3MBTL2 83746 3 2 15
TCGA L3MBTL2 83746 26 14 56

Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.  

 

Somatic mutations of L3MBTL2:

 

Generating mutation plots.

 

Highly correlated genes for L3MBTL2:

 

Showing top 20/41 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
L3MBTL2MRPL380.665561303
L3MBTL2RAMP30.665507303
L3MBTL2TUBGCP20.625391303
L3MBTL2PRR130.622522303
L3MBTL2OS90.610583303
L3MBTL2LRRC450.608865303
L3MBTL2NDP0.603106303
L3MBTL2PTMS0.601486303
L3MBTL2PPIP5K10.592598303
L3MBTL2CABIN10.585312504
L3MBTL2YDJC0.582157303
L3MBTL2RPUSD10.578466303
L3MBTL2PYGO20.576021303
L3MBTL2TBCB0.5718403
L3MBTL2RRBP10.569924403
L3MBTL2SLC27A10.56494403
L3MBTL2SETD1A0.562273503
L3MBTL2STK250.560281303
L3MBTL2LZTR10.559418404
L3MBTL2DNAL40.556619504

For details and further investigation, click here