| Full name: laccase domain containing 1 | Alias Symbol: FLJ38725|FAMIN | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 144811 | HGNC ID: HGNC:26789 | Ensembl Gene: ENSG00000179630 | OMIM ID: 613409 |
Expression of LACC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LACC1 | 144811 | 228937_at | -0.5380 | 0.1401 | |
| GSE26886 | LACC1 | 144811 | 228937_at | -1.4631 | 0.0022 | |
| GSE45670 | LACC1 | 144811 | 228937_at | -0.4761 | 0.0618 | |
| GSE53622 | LACC1 | 144811 | 24972 | -0.3448 | 0.0022 | |
| GSE53624 | LACC1 | 144811 | 24972 | -0.4895 | 0.0000 | |
| GSE63941 | LACC1 | 144811 | 228937_at | -4.0196 | 0.0003 | |
| GSE77861 | LACC1 | 144811 | 228937_at | -0.8497 | 0.0701 | |
| GSE97050 | LACC1 | 144811 | A_23_P374322 | 0.0442 | 0.8948 | |
| SRP007169 | LACC1 | 144811 | RNAseq | -0.5156 | 0.3627 | |
| SRP008496 | LACC1 | 144811 | RNAseq | 0.3860 | 0.3493 | |
| SRP064894 | LACC1 | 144811 | RNAseq | -0.3778 | 0.1465 | |
| SRP133303 | LACC1 | 144811 | RNAseq | -0.1895 | 0.3938 | |
| SRP159526 | LACC1 | 144811 | RNAseq | -0.8200 | 0.1454 | |
| SRP193095 | LACC1 | 144811 | RNAseq | -0.6528 | 0.0000 | |
| SRP219564 | LACC1 | 144811 | RNAseq | -0.4812 | 0.1376 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LACC1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LACC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LACC1 | 144811 | 0 | 13 | 17 | |
| GSE20123 | LACC1 | 144811 | 0 | 12 | 18 | |
| GSE43470 | LACC1 | 144811 | 3 | 13 | 27 | |
| GSE46452 | LACC1 | 144811 | 0 | 33 | 26 | |
| GSE47630 | LACC1 | 144811 | 2 | 27 | 11 | |
| GSE54993 | LACC1 | 144811 | 12 | 2 | 56 | |
| GSE54994 | LACC1 | 144811 | 1 | 16 | 36 | |
| GSE60625 | LACC1 | 144811 | 0 | 3 | 8 | |
| GSE74703 | LACC1 | 144811 | 3 | 10 | 23 | |
| GSE74704 | LACC1 | 144811 | 0 | 9 | 11 | |
| TCGA | LACC1 | 144811 | 8 | 39 | 49 |
Total number of gains: 29; Total number of losses: 177; Total Number of normals: 282.
Somatic mutations of LACC1:
Generating mutation plots.
Highly correlated genes for LACC1:
Showing top 20/438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LACC1 | TVP23B | 0.706627 | 4 | 0 | 4 |
| LACC1 | SUOX | 0.689322 | 3 | 0 | 3 |
| LACC1 | TMEM161B | 0.682811 | 3 | 0 | 3 |
| LACC1 | SLC11A2 | 0.67987 | 3 | 0 | 3 |
| LACC1 | RALA | 0.671758 | 6 | 0 | 5 |
| LACC1 | TRAPPC13 | 0.647805 | 6 | 0 | 6 |
| LACC1 | TMEM9B | 0.647183 | 5 | 0 | 5 |
| LACC1 | ITSN2 | 0.646541 | 5 | 0 | 4 |
| LACC1 | TRMT13 | 0.644432 | 3 | 0 | 3 |
| LACC1 | USP16 | 0.642881 | 6 | 0 | 4 |
| LACC1 | GID4 | 0.642664 | 4 | 0 | 4 |
| LACC1 | CCDC186 | 0.641983 | 6 | 0 | 5 |
| LACC1 | BLZF1 | 0.639582 | 5 | 0 | 4 |
| LACC1 | RBM3 | 0.639228 | 4 | 0 | 3 |
| LACC1 | NIPAL2 | 0.638841 | 4 | 0 | 3 |
| LACC1 | LGR4 | 0.638756 | 5 | 0 | 4 |
| LACC1 | FAM221A | 0.638494 | 4 | 0 | 3 |
| LACC1 | TMEM220 | 0.634613 | 5 | 0 | 4 |
| LACC1 | FIBIN | 0.633535 | 3 | 0 | 3 |
| LACC1 | MRPL39 | 0.630632 | 5 | 0 | 4 |
For details and further investigation, click here
