| Full name: lymphocyte cytosolic protein 1 | Alias Symbol: PLS2|CP64|L-PLASTIN|LC64P | ||
| Type: protein-coding gene | Cytoband: 13q14.13 | ||
| Entrez ID: 3936 | HGNC ID: HGNC:6528 | Ensembl Gene: ENSG00000136167 | OMIM ID: 153430 |
| Drug and gene relationship at DGIdb | |||
Expression of LCP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LCP1 | 3936 | 208885_at | 0.3603 | 0.8282 | |
| GSE20347 | LCP1 | 3936 | 208885_at | 0.1805 | 0.4267 | |
| GSE23400 | LCP1 | 3936 | 208885_at | 0.2299 | 0.0083 | |
| GSE26886 | LCP1 | 3936 | 208885_at | -0.2871 | 0.4263 | |
| GSE29001 | LCP1 | 3936 | 208885_at | 0.0888 | 0.6062 | |
| GSE38129 | LCP1 | 3936 | 208885_at | 0.1133 | 0.6325 | |
| GSE45670 | LCP1 | 3936 | 208885_at | 0.0352 | 0.9137 | |
| GSE53622 | LCP1 | 3936 | 69801 | 0.3679 | 0.0077 | |
| GSE53624 | LCP1 | 3936 | 69801 | -0.0767 | 0.6244 | |
| GSE63941 | LCP1 | 3936 | 208885_at | 1.9972 | 0.2273 | |
| GSE77861 | LCP1 | 3936 | 208885_at | 0.0312 | 0.8814 | |
| GSE97050 | LCP1 | 3936 | A_23_P204847 | 0.8914 | 0.0970 | |
| SRP007169 | LCP1 | 3936 | RNAseq | 1.1923 | 0.1005 | |
| SRP008496 | LCP1 | 3936 | RNAseq | 0.5481 | 0.2196 | |
| SRP064894 | LCP1 | 3936 | RNAseq | 0.6701 | 0.0290 | |
| SRP133303 | LCP1 | 3936 | RNAseq | 0.2129 | 0.3397 | |
| SRP159526 | LCP1 | 3936 | RNAseq | -0.4456 | 0.5701 | |
| SRP193095 | LCP1 | 3936 | RNAseq | 0.3726 | 0.1045 | |
| SRP219564 | LCP1 | 3936 | RNAseq | 0.7064 | 0.1856 | |
| TCGA | LCP1 | 3936 | RNAseq | 0.2177 | 0.0414 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCP1 | 3936 | 0 | 14 | 16 | |
| GSE20123 | LCP1 | 3936 | 0 | 13 | 17 | |
| GSE43470 | LCP1 | 3936 | 3 | 13 | 27 | |
| GSE46452 | LCP1 | 3936 | 0 | 33 | 26 | |
| GSE47630 | LCP1 | 3936 | 2 | 27 | 11 | |
| GSE54993 | LCP1 | 3936 | 12 | 2 | 56 | |
| GSE54994 | LCP1 | 3936 | 1 | 16 | 36 | |
| GSE60625 | LCP1 | 3936 | 0 | 3 | 8 | |
| GSE74703 | LCP1 | 3936 | 3 | 10 | 23 | |
| GSE74704 | LCP1 | 3936 | 0 | 10 | 10 | |
| TCGA | LCP1 | 3936 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 181; Total Number of normals: 279.
Somatic mutations of LCP1:
Generating mutation plots.
Highly correlated genes for LCP1:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCP1 | GPR141 | 0.738675 | 3 | 0 | 3 |
| LCP1 | ARHGAP15 | 0.734727 | 3 | 0 | 3 |
| LCP1 | TNFSF8 | 0.728888 | 4 | 0 | 4 |
| LCP1 | HLA-DMB | 0.725491 | 11 | 0 | 10 |
| LCP1 | CERKL | 0.724967 | 3 | 0 | 3 |
| LCP1 | CCR4 | 0.71529 | 3 | 0 | 3 |
| LCP1 | ITGB2 | 0.709593 | 11 | 0 | 11 |
| LCP1 | C19orf38 | 0.708311 | 3 | 0 | 3 |
| LCP1 | GPR132 | 0.7045 | 4 | 0 | 4 |
| LCP1 | DOK1 | 0.704074 | 4 | 0 | 3 |
| LCP1 | SNX20 | 0.702096 | 7 | 0 | 6 |
| LCP1 | PRKCSH | 0.701336 | 3 | 0 | 3 |
| LCP1 | CD53 | 0.697593 | 10 | 0 | 8 |
| LCP1 | LAPTM5 | 0.696252 | 11 | 0 | 10 |
| LCP1 | P2RY8 | 0.695384 | 4 | 0 | 3 |
| LCP1 | NCKAP1L | 0.694801 | 9 | 0 | 8 |
| LCP1 | SUCNR1 | 0.694435 | 4 | 0 | 3 |
| LCP1 | RHOH | 0.691628 | 8 | 0 | 7 |
| LCP1 | ITGB2-AS1 | 0.690473 | 3 | 0 | 3 |
| LCP1 | AOAH | 0.689594 | 6 | 0 | 5 |
For details and further investigation, click here
