LDHB

 

Full name: lactate dehydrogenase B Alias Symbol: 
Type: protein-coding gene Cytoband: 12p12.1
Entrez ID: 3945 HGNC ID: HGNC:6541 Ensembl Gene: ENSG00000111716 OMIM ID: 150100
Drug and gene relationship at DGIdb

 

Expression of LDHB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LDHB 3945 213564_x_at 0.5075 0.2545
GSE20347 LDHB 3945 213564_x_at 1.2985 0.0000
GSE23400 LDHB 3945 213564_x_at 0.8833 0.0000
GSE26886 LDHB 3945 213564_x_at 0.3802 0.1508
GSE29001 LDHB 3945 213564_x_at 0.5189 0.1880
GSE38129 LDHB 3945 213564_x_at 0.8351 0.0001
GSE45670 LDHB 3945 213564_x_at 0.4434 0.1306
GSE53622 LDHB 3945 21091 0.6983 0.0000
GSE53624 LDHB 3945 21091 1.1232 0.0000
GSE63941 LDHB 3945 213564_x_at 0.2582 0.4877
GSE77861 LDHB 3945 213564_x_at 1.3191 0.0025
GSE97050 LDHB 3945 A_23_P53476 0.2702 0.3225
SRP007169 LDHB 3945 RNAseq 1.6416 0.0000
SRP008496 LDHB 3945 RNAseq 1.6941 0.0000
SRP064894 LDHB 3945 RNAseq 0.6294 0.0007
SRP133303 LDHB 3945 RNAseq 1.0287 0.0000
SRP159526 LDHB 3945 RNAseq 0.9781 0.0090
SRP193095 LDHB 3945 RNAseq 0.6182 0.0012
SRP219564 LDHB 3945 RNAseq -0.1465 0.8079
TCGA LDHB 3945 RNAseq -0.0829 0.1625

Upregulated datasets: 6; Downregulated datasets: 0.  

 

Survival by LDHB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LDHB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LDHB 3945 9 2 19
GSE20123 LDHB 3945 9 2 19
GSE43470 LDHB 3945 9 4 30
GSE46452 LDHB 3945 10 1 48
GSE47630 LDHB 3945 14 1 25
GSE54993 LDHB 3945 1 9 60
GSE54994 LDHB 3945 11 2 40
GSE60625 LDHB 3945 0 1 10
GSE74703 LDHB 3945 9 3 24
GSE74704 LDHB 3945 6 1 13
TCGA LDHB 3945 42 5 49

Total number of gains: 120; Total number of losses: 31; Total Number of normals: 337.  

 

Somatic mutations of LDHB:

 

Generating mutation plots.

 

Highly correlated genes for LDHB:

 

Showing top 20/1373 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LDHBSSB0.6961651009
LDHBPPT10.6882751009
LDHBWDR810.686406303
LDHBIRF2BPL0.683237606
LDHBMSH60.67950612011
LDHBZC3H180.675403404
LDHBTMTC10.674675504
LDHBSCCPDH0.6743231008
LDHBMTERF30.673645505
LDHBHSPD10.6713891109
LDHBPFN20.66822413011
LDHBKLF130.666523504
LDHBCEBPZ0.663568707
LDHBCYP2S10.659054303
LDHBPDIA50.658249303
LDHBCALU0.6576711010
LDHBPSMD40.657582807
LDHBDESI20.657558908
LDHBCOLGALT10.657551909
LDHBPRDX30.657315807

For details and further investigation, click here