| Full name: LLP homolog, long-term synaptic facilitation factor | Alias Symbol: MGC14817|hLLP | ||
| Type: protein-coding gene | Cytoband: 12q14.3 | ||
| Entrez ID: 84298 | HGNC ID: HGNC:28229 | Ensembl Gene: ENSG00000139233 | OMIM ID: 616998 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LLPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LLPH | 84298 | 224446_at | 0.3800 | 0.4397 | |
| GSE20347 | LLPH | 84298 | 209779_at | 0.1105 | 0.0920 | |
| GSE23400 | LLPH | 84298 | 209779_at | -0.0066 | 0.7917 | |
| GSE26886 | LLPH | 84298 | 224446_at | -0.1806 | 0.4280 | |
| GSE29001 | LLPH | 84298 | 209779_at | 0.2350 | 0.1630 | |
| GSE38129 | LLPH | 84298 | 209779_at | 0.1091 | 0.0432 | |
| GSE45670 | LLPH | 84298 | 224446_at | 0.4535 | 0.0061 | |
| GSE53622 | LLPH | 84298 | 9058 | 0.5253 | 0.0000 | |
| GSE53624 | LLPH | 84298 | 9058 | 0.8418 | 0.0000 | |
| GSE63941 | LLPH | 84298 | 224446_at | 0.2157 | 0.5676 | |
| GSE77861 | LLPH | 84298 | 224446_at | 0.5493 | 0.1793 | |
| GSE97050 | LLPH | A_21_P0013970 | 0.2605 | 0.3082 | ||
| SRP007169 | LLPH | 84298 | RNAseq | 0.4809 | 0.2216 | |
| SRP008496 | LLPH | 84298 | RNAseq | 0.5887 | 0.0299 | |
| SRP064894 | LLPH | 84298 | RNAseq | 0.5959 | 0.0020 | |
| SRP133303 | LLPH | 84298 | RNAseq | 0.2936 | 0.0101 | |
| SRP159526 | LLPH | 84298 | RNAseq | 0.5913 | 0.1268 | |
| SRP193095 | LLPH | 84298 | RNAseq | 0.0981 | 0.1481 | |
| SRP219564 | LLPH | 84298 | RNAseq | 0.5335 | 0.2288 | |
| TCGA | LLPH | 84298 | RNAseq | 0.1716 | 0.0096 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LLPH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LLPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LLPH | 84298 | 5 | 1 | 24 | |
| GSE20123 | LLPH | 84298 | 5 | 1 | 24 | |
| GSE43470 | LLPH | 84298 | 5 | 0 | 38 | |
| GSE46452 | LLPH | 84298 | 13 | 0 | 46 | |
| GSE47630 | LLPH | 84298 | 10 | 1 | 29 | |
| GSE54993 | LLPH | 84298 | 0 | 7 | 63 | |
| GSE54994 | LLPH | 84298 | 6 | 1 | 46 | |
| GSE60625 | LLPH | 84298 | 0 | 0 | 11 | |
| GSE74703 | LLPH | 84298 | 5 | 0 | 31 | |
| GSE74704 | LLPH | 84298 | 4 | 1 | 15 | |
| TCGA | LLPH | 84298 | 24 | 9 | 63 |
Total number of gains: 77; Total number of losses: 21; Total Number of normals: 390.
Somatic mutations of LLPH:
Generating mutation plots.
Highly correlated genes for LLPH:
Showing top 20/814 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LLPH | RNF213 | 0.732734 | 3 | 0 | 3 |
| LLPH | TNFSF14 | 0.721346 | 3 | 0 | 3 |
| LLPH | FADS1 | 0.714901 | 3 | 0 | 3 |
| LLPH | B3GALT6 | 0.711338 | 3 | 0 | 3 |
| LLPH | CHMP5 | 0.707062 | 3 | 0 | 3 |
| LLPH | PYCR2 | 0.702195 | 3 | 0 | 3 |
| LLPH | HSPA8 | 0.701564 | 3 | 0 | 3 |
| LLPH | CCT2 | 0.688749 | 9 | 0 | 7 |
| LLPH | LYAR | 0.688367 | 5 | 0 | 5 |
| LLPH | MILR1 | 0.685978 | 3 | 0 | 3 |
| LLPH | CCP110 | 0.683937 | 4 | 0 | 4 |
| LLPH | FITM2 | 0.681355 | 3 | 0 | 3 |
| LLPH | NR2C1 | 0.680526 | 3 | 0 | 3 |
| LLPH | MRPL47 | 0.68001 | 6 | 0 | 6 |
| LLPH | CPT1C | 0.679859 | 4 | 0 | 4 |
| LLPH | RBBP9 | 0.679109 | 3 | 0 | 3 |
| LLPH | ANKRD13C | 0.678285 | 3 | 0 | 3 |
| LLPH | ATG10 | 0.678035 | 4 | 0 | 4 |
| LLPH | NUTF2 | 0.676064 | 6 | 0 | 5 |
| LLPH | ADAM9 | 0.675636 | 3 | 0 | 3 |
For details and further investigation, click here
