CCT2

 

Full name: chaperonin containing TCP1 subunit 2 Alias Symbol: Cctb
Type: protein-coding gene Cytoband: 12q15
Entrez ID: 10576 HGNC ID: HGNC:1615 Ensembl Gene: ENSG00000166226 OMIM ID: 605139
Drug and gene relationship at DGIdb

 

Expression of CCT2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCT2 10576 201947_s_at 0.5361 0.0965
GSE20347 CCT2 10576 201947_s_at 0.7924 0.0000
GSE23400 CCT2 10576 201947_s_at 0.8959 0.0000
GSE26886 CCT2 10576 201947_s_at 0.3565 0.0027
GSE29001 CCT2 10576 201947_s_at 0.6866 0.1872
GSE38129 CCT2 10576 201947_s_at 0.9100 0.0000
GSE45670 CCT2 10576 201947_s_at 0.4837 0.0038
GSE53622 CCT2 10576 71192 0.7316 0.0000
GSE53624 CCT2 10576 71192 0.9963 0.0000
GSE63941 CCT2 10576 201947_s_at 0.5865 0.2203
GSE77861 CCT2 10576 201947_s_at 0.6076 0.0163
GSE97050 CCT2 10576 A_23_P105392 0.5298 0.1133
SRP007169 CCT2 10576 RNAseq 0.1045 0.7477
SRP008496 CCT2 10576 RNAseq 0.1730 0.2998
SRP064894 CCT2 10576 RNAseq 0.5080 0.0018
SRP133303 CCT2 10576 RNAseq 1.3898 0.0001
SRP159526 CCT2 10576 RNAseq 0.8074 0.0483
SRP193095 CCT2 10576 RNAseq 0.3546 0.0216
TCGA CCT2 10576 RNAseq 0.2373 0.0001

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by CCT2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCT2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCT2 10576 6 1 23
GSE20123 CCT2 10576 6 0 24
GSE43470 CCT2 10576 4 0 39
GSE46452 CCT2 10576 11 1 47
GSE47630 CCT2 10576 10 1 29
GSE54993 CCT2 10576 0 6 64
GSE54994 CCT2 10576 8 1 44
GSE60625 CCT2 10576 0 0 11
GSE74703 CCT2 10576 4 0 32
GSE74704 CCT2 10576 5 0 15
TCGA CCT2 10576 23 8 65

Total number of gains: 77; Total number of losses: 18; Total Number of normals: 393.  

 

Somatic mutations of CCT2:

 

Generating mutation plots.

 

Highly correlated genes for CCT2:

 

Showing top 20/1984 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCT2INTS100.80061303
CCT2NUP1070.78363813013
CCT2FARS20.767844303
CCT2ELP40.756231303
CCT2TTL0.751096707
CCT2PYCR20.750784303
CCT2EBNA1BP20.749703404
CCT2MAPKAPK50.7444811011
CCT2MMS22L0.743915303
CCT2FADS10.738933303
CCT2TRAF70.737226404
CCT2MCM60.73370311010
CCT2RUVBL10.73249913013
CCT2ILF20.73046212011
CCT2EFTUD20.729948707
CCT2CCT40.72601612010
CCT2SPON20.724861303
CCT2NOP560.724297303
CCT2DHRS130.723243303
CCT2PTCD10.72231303

For details and further investigation, click here