| Full name: aryl-hydrocarbon receptor repressor | Alias Symbol: KIAA1234|bHLHe77 | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 57491 | HGNC ID: HGNC:346 | Ensembl Gene: ENSG00000063438 | OMIM ID: 606517 |
| Drug and gene relationship at DGIdb | |||
Expression of AHRR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHRR | 57491 | 229354_at | -0.5064 | 0.5235 | |
| GSE26886 | AHRR | 57491 | 229354_at | -0.5319 | 0.1180 | |
| GSE45670 | AHRR | 57491 | 229354_at | -0.3698 | 0.0591 | |
| GSE53622 | AHRR | 57491 | 114017 | -0.9789 | 0.0000 | |
| GSE53624 | AHRR | 57491 | 114017 | -1.2281 | 0.0000 | |
| GSE63941 | AHRR | 57491 | 229354_at | -2.7637 | 0.0020 | |
| GSE77861 | AHRR | 57491 | 229354_at | 0.0309 | 0.8411 | |
| GSE97050 | AHRR | 57491 | A_23_P358709 | -0.1658 | 0.6361 | |
| SRP007169 | AHRR | 57491 | RNAseq | -0.8964 | 0.1346 | |
| SRP064894 | AHRR | 57491 | RNAseq | -1.8675 | 0.0000 | |
| SRP133303 | AHRR | 57491 | RNAseq | -0.8561 | 0.0004 | |
| SRP159526 | AHRR | 57491 | RNAseq | -0.8748 | 0.0261 | |
| SRP193095 | AHRR | 57491 | RNAseq | -0.2746 | 0.1341 | |
| SRP219564 | AHRR | 57491 | RNAseq | -1.4748 | 0.0109 | |
| TCGA | AHRR | 57491 | RNAseq | -0.1223 | 0.4944 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by AHRR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHRR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHRR | 57491 | 13 | 1 | 16 | |
| GSE20123 | AHRR | 57491 | 13 | 1 | 16 | |
| GSE43470 | AHRR | 57491 | 16 | 0 | 27 | |
| GSE46452 | AHRR | 57491 | 6 | 22 | 31 | |
| GSE47630 | AHRR | 57491 | 11 | 9 | 20 | |
| GSE54993 | AHRR | 57491 | 5 | 6 | 59 | |
| GSE54994 | AHRR | 57491 | 29 | 1 | 23 | |
| GSE60625 | AHRR | 57491 | 0 | 0 | 11 | |
| GSE74703 | AHRR | 57491 | 13 | 0 | 23 | |
| GSE74704 | AHRR | 57491 | 11 | 0 | 9 | |
| TCGA | AHRR | 57491 | 60 | 4 | 32 |
Total number of gains: 177; Total number of losses: 44; Total Number of normals: 267.
Somatic mutations of AHRR:
Generating mutation plots.
Highly correlated genes for AHRR:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHRR | FGF7 | 0.783142 | 3 | 0 | 3 |
| AHRR | APPBP2 | 0.728509 | 3 | 0 | 3 |
| AHRR | TRPC6 | 0.713055 | 3 | 0 | 3 |
| AHRR | MRC2 | 0.713046 | 3 | 0 | 3 |
| AHRR | ITGB5 | 0.707419 | 3 | 0 | 3 |
| AHRR | GLTP | 0.702144 | 4 | 0 | 4 |
| AHRR | ZNF521 | 0.697229 | 4 | 0 | 4 |
| AHRR | C3orf80 | 0.69671 | 3 | 0 | 3 |
| AHRR | ZNF585A | 0.695237 | 3 | 0 | 3 |
| AHRR | THAP2 | 0.693626 | 3 | 0 | 3 |
| AHRR | LMCD1 | 0.692008 | 3 | 0 | 3 |
| AHRR | HOOK3 | 0.677071 | 3 | 0 | 3 |
| AHRR | SACM1L | 0.676838 | 3 | 0 | 3 |
| AHRR | CANT1 | 0.675505 | 3 | 0 | 3 |
| AHRR | PDLIM2 | 0.67361 | 4 | 0 | 4 |
| AHRR | MBD2 | 0.673337 | 4 | 0 | 3 |
| AHRR | BACH1 | 0.67296 | 4 | 0 | 3 |
| AHRR | UNC13B | 0.668905 | 3 | 0 | 3 |
| AHRR | DTWD1 | 0.668293 | 3 | 0 | 3 |
| AHRR | SLC46A2 | 0.665471 | 5 | 0 | 4 |
For details and further investigation, click here
