| Full name: leucine rich pentatricopeptide repeat containing | Alias Symbol: GP130|LRP130 | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 10128 | HGNC ID: HGNC:15714 | Ensembl Gene: ENSG00000138095 | OMIM ID: 607544 |
Screen Evidence:
| |||
Expression of LRPPRC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRPPRC | 10128 | 211971_s_at | 0.4618 | 0.0553 | |
| GSE20347 | LRPPRC | 10128 | 211971_s_at | 0.6439 | 0.0001 | |
| GSE23400 | LRPPRC | 10128 | 211971_s_at | 0.6912 | 0.0000 | |
| GSE26886 | LRPPRC | 10128 | 211615_s_at | 0.3997 | 0.0137 | |
| GSE29001 | LRPPRC | 10128 | 211615_s_at | 0.3481 | 0.1670 | |
| GSE38129 | LRPPRC | 10128 | 211971_s_at | 0.7331 | 0.0000 | |
| GSE45670 | LRPPRC | 10128 | 211971_s_at | 0.3880 | 0.0091 | |
| GSE53622 | LRPPRC | 10128 | 30372 | 0.4675 | 0.0000 | |
| GSE53624 | LRPPRC | 10128 | 30372 | 0.5756 | 0.0000 | |
| GSE63941 | LRPPRC | 10128 | 211971_s_at | 1.0277 | 0.0100 | |
| GSE77861 | LRPPRC | 10128 | 211971_s_at | 0.5757 | 0.0542 | |
| GSE97050 | LRPPRC | 10128 | A_33_P3388855 | 0.4540 | 0.2662 | |
| SRP007169 | LRPPRC | 10128 | RNAseq | 1.4906 | 0.0001 | |
| SRP008496 | LRPPRC | 10128 | RNAseq | 1.3442 | 0.0000 | |
| SRP064894 | LRPPRC | 10128 | RNAseq | 0.1499 | 0.3028 | |
| SRP133303 | LRPPRC | 10128 | RNAseq | 0.3614 | 0.0282 | |
| SRP159526 | LRPPRC | 10128 | RNAseq | 0.5985 | 0.0462 | |
| SRP193095 | LRPPRC | 10128 | RNAseq | 0.2420 | 0.0252 | |
| SRP219564 | LRPPRC | 10128 | RNAseq | 0.2792 | 0.3459 | |
| TCGA | LRPPRC | 10128 | RNAseq | 0.0705 | 0.0879 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LRPPRC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRPPRC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRPPRC | 10128 | 10 | 1 | 19 | |
| GSE20123 | LRPPRC | 10128 | 9 | 1 | 20 | |
| GSE43470 | LRPPRC | 10128 | 4 | 0 | 39 | |
| GSE46452 | LRPPRC | 10128 | 1 | 4 | 54 | |
| GSE47630 | LRPPRC | 10128 | 7 | 0 | 33 | |
| GSE54993 | LRPPRC | 10128 | 0 | 5 | 65 | |
| GSE54994 | LRPPRC | 10128 | 10 | 0 | 43 | |
| GSE60625 | LRPPRC | 10128 | 0 | 3 | 8 | |
| GSE74703 | LRPPRC | 10128 | 4 | 0 | 32 | |
| GSE74704 | LRPPRC | 10128 | 9 | 1 | 10 | |
| TCGA | LRPPRC | 10128 | 35 | 2 | 59 |
Total number of gains: 89; Total number of losses: 17; Total Number of normals: 382.
Somatic mutations of LRPPRC:
Generating mutation plots.
Highly correlated genes for LRPPRC:
Showing top 20/1444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRPPRC | PDIA6 | 0.72565 | 10 | 0 | 9 |
| LRPPRC | TRMT61B | 0.723721 | 10 | 0 | 10 |
| LRPPRC | CCT4 | 0.714559 | 13 | 0 | 12 |
| LRPPRC | NUP93 | 0.714369 | 9 | 0 | 9 |
| LRPPRC | PNPT1 | 0.71161 | 7 | 0 | 7 |
| LRPPRC | DAP3 | 0.702794 | 12 | 0 | 11 |
| LRPPRC | HSPE1 | 0.701118 | 11 | 0 | 10 |
| LRPPRC | RFC4 | 0.699959 | 12 | 0 | 11 |
| LRPPRC | HSPD1 | 0.696377 | 12 | 0 | 11 |
| LRPPRC | PTCD3 | 0.696325 | 12 | 0 | 11 |
| LRPPRC | XPO1 | 0.695669 | 13 | 0 | 12 |
| LRPPRC | ILF2 | 0.69448 | 12 | 0 | 11 |
| LRPPRC | PRKDC | 0.69376 | 12 | 0 | 11 |
| LRPPRC | KIF23 | 0.693582 | 11 | 0 | 11 |
| LRPPRC | CAD | 0.692191 | 13 | 0 | 12 |
| LRPPRC | PSME4 | 0.690275 | 12 | 0 | 11 |
| LRPPRC | NOL11 | 0.689753 | 13 | 0 | 12 |
| LRPPRC | COX7A2L | 0.689312 | 12 | 0 | 11 |
| LRPPRC | PSMA4 | 0.684792 | 9 | 0 | 9 |
| LRPPRC | NDUFAF7 | 0.684381 | 10 | 0 | 10 |
For details and further investigation, click here
