| Full name: kinesin family member 23 | Alias Symbol: MKLP1|MKLP-1 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 9493 | HGNC ID: HGNC:6392 | Ensembl Gene: | OMIM ID: 605064 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF23 | 9493 | 204709_s_at | 1.4501 | 0.0200 | |
| GSE20347 | KIF23 | 9493 | 204709_s_at | 2.1670 | 0.0000 | |
| GSE23400 | KIF23 | 9493 | 204709_s_at | 0.5262 | 0.0000 | |
| GSE26886 | KIF23 | 9493 | 204709_s_at | 0.5959 | 0.1528 | |
| GSE29001 | KIF23 | 9493 | 204709_s_at | 1.7057 | 0.0001 | |
| GSE38129 | KIF23 | 9493 | 204709_s_at | 2.3811 | 0.0000 | |
| GSE45670 | KIF23 | 9493 | 204709_s_at | 1.4007 | 0.0000 | |
| GSE53622 | KIF23 | 9493 | 37392 | 1.8146 | 0.0000 | |
| GSE53624 | KIF23 | 9493 | 146179 | 1.9744 | 0.0000 | |
| GSE63941 | KIF23 | 9493 | 204709_s_at | 1.8105 | 0.0096 | |
| GSE77861 | KIF23 | 9493 | 204709_s_at | 0.9836 | 0.0578 | |
| GSE97050 | KIF23 | 9493 | A_33_P3311755 | 1.0368 | 0.2121 | |
| SRP007169 | KIF23 | 9493 | RNAseq | 2.1038 | 0.0000 | |
| SRP008496 | KIF23 | 9493 | RNAseq | 1.6431 | 0.0000 | |
| SRP064894 | KIF23 | 9493 | RNAseq | 1.5449 | 0.0000 | |
| SRP133303 | KIF23 | 9493 | RNAseq | 1.7914 | 0.0000 | |
| SRP159526 | KIF23 | 9493 | RNAseq | 1.4838 | 0.0001 | |
| SRP193095 | KIF23 | 9493 | RNAseq | 1.2625 | 0.0000 | |
| SRP219564 | KIF23 | 9493 | RNAseq | 1.2326 | 0.0112 | |
| TCGA | KIF23 | 9493 | RNAseq | 1.0949 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by KIF23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF23 | 9493 | 7 | 1 | 22 | |
| GSE20123 | KIF23 | 9493 | 7 | 1 | 22 | |
| GSE43470 | KIF23 | 9493 | 4 | 6 | 33 | |
| GSE46452 | KIF23 | 9493 | 3 | 7 | 49 | |
| GSE47630 | KIF23 | 9493 | 8 | 10 | 22 | |
| GSE54993 | KIF23 | 9493 | 5 | 6 | 59 | |
| GSE54994 | KIF23 | 9493 | 5 | 7 | 41 | |
| GSE60625 | KIF23 | 9493 | 4 | 0 | 7 | |
| GSE74703 | KIF23 | 9493 | 4 | 3 | 29 | |
| GSE74704 | KIF23 | 9493 | 3 | 1 | 16 | |
| TCGA | KIF23 | 9493 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 57; Total Number of normals: 371.
Somatic mutations of KIF23:
Generating mutation plots.
Highly correlated genes for KIF23:
Showing top 20/2025 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF23 | CCNB2 | 0.859835 | 12 | 0 | 12 |
| KIF23 | ANLN | 0.852306 | 9 | 0 | 9 |
| KIF23 | DEPDC1B | 0.843467 | 7 | 0 | 7 |
| KIF23 | CEP55 | 0.84117 | 13 | 0 | 12 |
| KIF23 | PRC1 | 0.840845 | 13 | 0 | 13 |
| KIF23 | CDK1 | 0.836946 | 12 | 0 | 12 |
| KIF23 | BUB1B | 0.836053 | 10 | 0 | 10 |
| KIF23 | KIF14 | 0.83521 | 13 | 0 | 13 |
| KIF23 | CENPF | 0.833693 | 12 | 0 | 12 |
| KIF23 | BUB1 | 0.833289 | 11 | 0 | 11 |
| KIF23 | MMS22L | 0.831273 | 3 | 0 | 3 |
| KIF23 | KNSTRN | 0.829061 | 7 | 0 | 7 |
| KIF23 | TTK | 0.828677 | 12 | 0 | 12 |
| KIF23 | KIF20A | 0.820328 | 13 | 0 | 12 |
| KIF23 | CDKN3 | 0.819738 | 13 | 0 | 13 |
| KIF23 | NUF2 | 0.817893 | 9 | 0 | 8 |
| KIF23 | TPX2 | 0.81748 | 13 | 0 | 13 |
| KIF23 | CDC20 | 0.815027 | 11 | 0 | 11 |
| KIF23 | ASPM | 0.812336 | 13 | 0 | 12 |
| KIF23 | RACGAP1 | 0.811195 | 11 | 0 | 11 |
For details and further investigation, click here
