PTCD3

 

Full name: pentatricopeptide repeat domain 3 Alias Symbol: FLJ20758|DKFZp666K071
Type: protein-coding gene Cytoband: 2p11.2
Entrez ID: 55037 HGNC ID: HGNC:24717 Ensembl Gene: ENSG00000132300 OMIM ID: 614918
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of PTCD3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PTCD3 55037 217895_at 0.4189 0.0591
GSE20347 PTCD3 55037 217895_at 0.6394 0.0000
GSE23400 PTCD3 55037 217895_at 0.5286 0.0000
GSE26886 PTCD3 55037 217895_at 0.1050 0.5579
GSE29001 PTCD3 55037 217895_at 0.2707 0.2539
GSE38129 PTCD3 55037 217895_at 0.5810 0.0000
GSE45670 PTCD3 55037 217895_at 0.5555 0.0054
GSE53622 PTCD3 55037 39956 0.4842 0.0000
GSE53624 PTCD3 55037 39956 0.5571 0.0000
GSE63941 PTCD3 55037 217895_at 0.4871 0.2099
GSE77861 PTCD3 55037 217895_at 0.6472 0.0321
GSE97050 PTCD3 55037 A_33_P3290945 0.4023 0.1862
SRP007169 PTCD3 55037 RNAseq 0.5810 0.0914
SRP008496 PTCD3 55037 RNAseq 0.6485 0.0080
SRP064894 PTCD3 55037 RNAseq 0.2477 0.1319
SRP133303 PTCD3 55037 RNAseq 0.3146 0.0014
SRP159526 PTCD3 55037 RNAseq 0.5360 0.0112
SRP193095 PTCD3 55037 RNAseq 0.1306 0.1162
SRP219564 PTCD3 55037 RNAseq 0.2370 0.5459
TCGA PTCD3 55037 RNAseq 0.0229 0.6288

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PTCD3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PTCD3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PTCD3 55037 9 2 19
GSE20123 PTCD3 55037 9 2 19
GSE43470 PTCD3 55037 4 2 37
GSE46452 PTCD3 55037 2 3 54
GSE47630 PTCD3 55037 7 0 33
GSE54993 PTCD3 55037 0 6 64
GSE54994 PTCD3 55037 10 0 43
GSE60625 PTCD3 55037 0 3 8
GSE74703 PTCD3 55037 4 1 31
GSE74704 PTCD3 55037 7 0 13
TCGA PTCD3 55037 35 4 57

Total number of gains: 87; Total number of losses: 23; Total Number of normals: 378.  

 

Somatic mutations of PTCD3:

 

Generating mutation plots.

 

Highly correlated genes for PTCD3:

 

Showing top 20/1687 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PTCD3PHF5A0.758975404
PTCD3NUDCD10.757539404
PTCD3IGFBP40.746918303
PTCD3ZNF7780.746024303
PTCD3PXN0.744594404
PTCD3CEP410.737204303
PTCD3IL1B0.728283404
PTCD3RNF1810.725437303
PTCD3RTTN0.7185303
PTCD3MBNL10.716057303
PTCD3CDCA20.714274504
PTCD3U2SURP0.712762808
PTCD3USP390.71134311010
PTCD3SIX40.711225606
PTCD3HAS30.706418404
PTCD3TMC70.706064303
PTCD3MPV170.705689606
PTCD3ZNF6640.705344303
PTCD3XPO10.70391112011
PTCD3IMMT0.7037771109

For details and further investigation, click here