| Full name: leucine rich repeat containing 32 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 2615 | HGNC ID: HGNC:4161 | Ensembl Gene: ENSG00000137507 | OMIM ID: 137207 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC32 | 2615 | 203835_at | 0.3454 | 0.3841 | |
| GSE20347 | LRRC32 | 2615 | 203835_at | 0.3156 | 0.0236 | |
| GSE23400 | LRRC32 | 2615 | 203835_at | 0.2015 | 0.0053 | |
| GSE26886 | LRRC32 | 2615 | 203835_at | 0.3017 | 0.1039 | |
| GSE29001 | LRRC32 | 2615 | 203835_at | 0.0461 | 0.8107 | |
| GSE38129 | LRRC32 | 2615 | 203835_at | 0.0134 | 0.9590 | |
| GSE45670 | LRRC32 | 2615 | 203835_at | -0.3340 | 0.1443 | |
| GSE53622 | LRRC32 | 2615 | 69055 | -0.4969 | 0.0000 | |
| GSE53624 | LRRC32 | 2615 | 69055 | -0.4543 | 0.0000 | |
| GSE63941 | LRRC32 | 2615 | 203835_at | -2.8920 | 0.0000 | |
| GSE77861 | LRRC32 | 2615 | 203835_at | 0.2686 | 0.1268 | |
| GSE97050 | LRRC32 | 2615 | A_24_P389916 | -0.1937 | 0.4850 | |
| SRP007169 | LRRC32 | 2615 | RNAseq | 2.0029 | 0.0230 | |
| SRP008496 | LRRC32 | 2615 | RNAseq | 2.1600 | 0.0006 | |
| SRP064894 | LRRC32 | 2615 | RNAseq | 0.4209 | 0.2166 | |
| SRP133303 | LRRC32 | 2615 | RNAseq | 0.3294 | 0.1400 | |
| SRP159526 | LRRC32 | 2615 | RNAseq | 0.1396 | 0.6267 | |
| SRP193095 | LRRC32 | 2615 | RNAseq | 1.7598 | 0.0000 | |
| SRP219564 | LRRC32 | 2615 | RNAseq | 0.3182 | 0.5947 | |
| TCGA | LRRC32 | 2615 | RNAseq | -0.3038 | 0.0026 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by LRRC32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC32 | 2615 | 5 | 9 | 16 | |
| GSE20123 | LRRC32 | 2615 | 5 | 8 | 17 | |
| GSE43470 | LRRC32 | 2615 | 5 | 1 | 37 | |
| GSE46452 | LRRC32 | 2615 | 7 | 22 | 30 | |
| GSE47630 | LRRC32 | 2615 | 5 | 16 | 19 | |
| GSE54993 | LRRC32 | 2615 | 8 | 2 | 60 | |
| GSE54994 | LRRC32 | 2615 | 6 | 17 | 30 | |
| GSE60625 | LRRC32 | 2615 | 4 | 3 | 4 | |
| GSE74703 | LRRC32 | 2615 | 3 | 1 | 32 | |
| GSE74704 | LRRC32 | 2615 | 3 | 4 | 13 | |
| TCGA | LRRC32 | 2615 | 20 | 31 | 45 |
Total number of gains: 71; Total number of losses: 114; Total Number of normals: 303.
Somatic mutations of LRRC32:
Generating mutation plots.
Highly correlated genes for LRRC32:
Showing top 20/541 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC32 | RASGRF2 | 0.677441 | 3 | 0 | 3 |
| LRRC32 | FNDC1 | 0.655066 | 5 | 0 | 5 |
| LRRC32 | RARRES2 | 0.651218 | 11 | 0 | 9 |
| LRRC32 | ASB1 | 0.650615 | 4 | 0 | 4 |
| LRRC32 | PDGFRB | 0.650555 | 10 | 0 | 7 |
| LRRC32 | MXRA8 | 0.647764 | 10 | 0 | 9 |
| LRRC32 | P4HA3 | 0.644483 | 4 | 0 | 4 |
| LRRC32 | OSR1 | 0.643949 | 5 | 0 | 3 |
| LRRC32 | GNG11 | 0.641123 | 8 | 0 | 8 |
| LRRC32 | DIABLO | 0.640444 | 3 | 0 | 3 |
| LRRC32 | HEXA | 0.639206 | 5 | 0 | 4 |
| LRRC32 | MAP7D1 | 0.637399 | 3 | 0 | 3 |
| LRRC32 | EBF1 | 0.63701 | 7 | 0 | 6 |
| LRRC32 | S1PR1 | 0.635844 | 6 | 0 | 5 |
| LRRC32 | GALNT15 | 0.633729 | 5 | 0 | 4 |
| LRRC32 | CLEC1A | 0.632965 | 5 | 0 | 5 |
| LRRC32 | TNFAIP6 | 0.632342 | 8 | 0 | 7 |
| LRRC32 | LAMA2 | 0.63121 | 9 | 0 | 7 |
| LRRC32 | ANGPTL2 | 0.629241 | 11 | 0 | 10 |
| LRRC32 | C11orf96 | 0.628079 | 4 | 0 | 3 |
For details and further investigation, click here
