| Full name: leucine rich repeat containing 37 member A2 | Alias Symbol: FLJ45049 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 474170 | HGNC ID: HGNC:32404 | Ensembl Gene: ENSG00000238083 | OMIM ID: 616556 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC37A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC37A2 | 474170 | 224686_x_at | -0.4505 | 0.4479 | |
| GSE26886 | LRRC37A2 | 474170 | 224686_x_at | -0.4382 | 0.1076 | |
| GSE45670 | LRRC37A2 | 474170 | 224686_x_at | 0.0375 | 0.8840 | |
| GSE53622 | LRRC37A2 | 474170 | 110081 | -0.9146 | 0.0000 | |
| GSE53624 | LRRC37A2 | 474170 | 110081 | -0.9473 | 0.0000 | |
| GSE63941 | LRRC37A2 | 474170 | 224686_x_at | 0.2287 | 0.6320 | |
| GSE77861 | LRRC37A2 | 474170 | 224686_x_at | 0.5459 | 0.3151 | |
| GSE97050 | LRRC37A2 | 474170 | A_24_P238143 | -0.5306 | 0.1823 | |
| SRP007169 | LRRC37A2 | 474170 | RNAseq | 0.2194 | 0.6979 | |
| SRP064894 | LRRC37A2 | 474170 | RNAseq | -0.2914 | 0.2642 | |
| SRP133303 | LRRC37A2 | 474170 | RNAseq | -0.2767 | 0.2502 | |
| SRP159526 | LRRC37A2 | 474170 | RNAseq | -0.4846 | 0.0749 | |
| SRP193095 | LRRC37A2 | 474170 | RNAseq | -0.2392 | 0.2661 | |
| SRP219564 | LRRC37A2 | 474170 | RNAseq | -0.5058 | 0.3163 | |
| TCGA | LRRC37A2 | 474170 | RNAseq | -0.1457 | 0.0925 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC37A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC37A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC37A2 | 474170 | 5 | 2 | 23 | |
| GSE20123 | LRRC37A2 | 474170 | 5 | 2 | 23 | |
| GSE43470 | LRRC37A2 | 474170 | 1 | 2 | 40 | |
| GSE46452 | LRRC37A2 | 474170 | 32 | 0 | 27 | |
| GSE47630 | LRRC37A2 | 474170 | 9 | 0 | 31 | |
| GSE54993 | LRRC37A2 | 474170 | 3 | 4 | 63 | |
| GSE54994 | LRRC37A2 | 474170 | 11 | 5 | 37 | |
| GSE60625 | LRRC37A2 | 474170 | 4 | 0 | 7 | |
| GSE74703 | LRRC37A2 | 474170 | 1 | 1 | 34 | |
| GSE74704 | LRRC37A2 | 474170 | 4 | 1 | 15 | |
| TCGA | LRRC37A2 | 474170 | 26 | 7 | 63 |
Total number of gains: 101; Total number of losses: 24; Total Number of normals: 363.
Somatic mutations of LRRC37A2:
Generating mutation plots.
Highly correlated genes for LRRC37A2:
Showing top 20/148 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC37A2 | TRA2A | 0.71839 | 3 | 0 | 3 |
| LRRC37A2 | CLDND1 | 0.712787 | 3 | 0 | 3 |
| LRRC37A2 | SLC10A5 | 0.691843 | 3 | 0 | 3 |
| LRRC37A2 | USP47 | 0.684325 | 3 | 0 | 3 |
| LRRC37A2 | HADHB | 0.678952 | 4 | 0 | 4 |
| LRRC37A2 | YOD1 | 0.672781 | 3 | 0 | 3 |
| LRRC37A2 | RABGAP1 | 0.672737 | 4 | 0 | 3 |
| LRRC37A2 | ZDHHC21 | 0.672528 | 3 | 0 | 3 |
| LRRC37A2 | LRRC37A3 | 0.67074 | 7 | 0 | 5 |
| LRRC37A2 | SYNRG | 0.669918 | 4 | 0 | 4 |
| LRRC37A2 | USP45 | 0.669882 | 3 | 0 | 3 |
| LRRC37A2 | MKNK2 | 0.668304 | 4 | 0 | 4 |
| LRRC37A2 | GOLPH3L | 0.665529 | 3 | 0 | 3 |
| LRRC37A2 | IRF2BP2 | 0.660316 | 3 | 0 | 3 |
| LRRC37A2 | TCP11L2 | 0.65544 | 3 | 0 | 3 |
| LRRC37A2 | SESTD1 | 0.652522 | 3 | 0 | 3 |
| LRRC37A2 | PLXNA2 | 0.652478 | 3 | 0 | 3 |
| LRRC37A2 | KPNA5 | 0.649875 | 4 | 0 | 3 |
| LRRC37A2 | ANKRD40 | 0.649394 | 3 | 0 | 3 |
| LRRC37A2 | N4BP3 | 0.645843 | 4 | 0 | 3 |
For details and further investigation, click here
