| Full name: RAB GTPase activating protein 1 | Alias Symbol: GAPCenA|TBC1D11 | ||
| Type: protein-coding gene | Cytoband: 9q33.2-q33.3 | ||
| Entrez ID: 23637 | HGNC ID: HGNC:17155 | Ensembl Gene: ENSG00000011454 | OMIM ID: 615882 |
| Drug and gene relationship at DGIdb | |||
Expression of RABGAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RABGAP1 | 23637 | 204028_s_at | -0.6347 | 0.1144 | |
| GSE20347 | RABGAP1 | 23637 | 204028_s_at | -0.3185 | 0.0025 | |
| GSE23400 | RABGAP1 | 23637 | 213313_at | -0.1302 | 0.1076 | |
| GSE26886 | RABGAP1 | 23637 | 204028_s_at | -0.9814 | 0.0003 | |
| GSE29001 | RABGAP1 | 23637 | 213313_at | 0.1219 | 0.4928 | |
| GSE38129 | RABGAP1 | 23637 | 213313_at | -0.3990 | 0.0040 | |
| GSE45670 | RABGAP1 | 23637 | 213313_at | -0.4316 | 0.0003 | |
| GSE53622 | RABGAP1 | 23637 | 119792 | -0.3608 | 0.0000 | |
| GSE53624 | RABGAP1 | 23637 | 119792 | -0.3556 | 0.0000 | |
| GSE63941 | RABGAP1 | 23637 | 213313_at | 0.4445 | 0.2452 | |
| GSE77861 | RABGAP1 | 23637 | 213313_at | -0.0150 | 0.9425 | |
| GSE97050 | RABGAP1 | 23637 | A_24_P252575 | -0.8039 | 0.0555 | |
| SRP007169 | RABGAP1 | 23637 | RNAseq | -0.1153 | 0.7241 | |
| SRP008496 | RABGAP1 | 23637 | RNAseq | -0.1076 | 0.6402 | |
| SRP064894 | RABGAP1 | 23637 | RNAseq | -0.4695 | 0.0057 | |
| SRP133303 | RABGAP1 | 23637 | RNAseq | -0.3779 | 0.0545 | |
| SRP159526 | RABGAP1 | 23637 | RNAseq | -0.4767 | 0.0094 | |
| SRP193095 | RABGAP1 | 23637 | RNAseq | -0.3414 | 0.0043 | |
| SRP219564 | RABGAP1 | 23637 | RNAseq | -0.5037 | 0.2211 | |
| TCGA | RABGAP1 | 23637 | RNAseq | -0.0716 | 0.1442 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RABGAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RABGAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RABGAP1 | 23637 | 3 | 9 | 18 | |
| GSE20123 | RABGAP1 | 23637 | 3 | 9 | 18 | |
| GSE43470 | RABGAP1 | 23637 | 5 | 4 | 34 | |
| GSE46452 | RABGAP1 | 23637 | 6 | 13 | 40 | |
| GSE47630 | RABGAP1 | 23637 | 3 | 16 | 21 | |
| GSE54993 | RABGAP1 | 23637 | 3 | 3 | 64 | |
| GSE54994 | RABGAP1 | 23637 | 9 | 10 | 34 | |
| GSE60625 | RABGAP1 | 23637 | 0 | 0 | 11 | |
| GSE74703 | RABGAP1 | 23637 | 5 | 3 | 28 | |
| GSE74704 | RABGAP1 | 23637 | 2 | 6 | 12 | |
| TCGA | RABGAP1 | 23637 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 97; Total Number of normals: 325.
Somatic mutations of RABGAP1:
Generating mutation plots.
Highly correlated genes for RABGAP1:
Showing top 20/613 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RABGAP1 | PDCD4 | 0.814001 | 3 | 0 | 3 |
| RABGAP1 | ZNF175 | 0.766558 | 3 | 0 | 3 |
| RABGAP1 | ZBTB26 | 0.763903 | 3 | 0 | 3 |
| RABGAP1 | RHBDF1 | 0.750093 | 3 | 0 | 3 |
| RABGAP1 | FBXO30 | 0.747564 | 3 | 0 | 3 |
| RABGAP1 | MYH3 | 0.742712 | 3 | 0 | 3 |
| RABGAP1 | CETN2 | 0.737279 | 3 | 0 | 3 |
| RABGAP1 | NFIA | 0.731394 | 6 | 0 | 5 |
| RABGAP1 | TMEM132C | 0.728874 | 3 | 0 | 3 |
| RABGAP1 | HDHD2 | 0.728527 | 4 | 0 | 3 |
| RABGAP1 | RPL14 | 0.722475 | 3 | 0 | 3 |
| RABGAP1 | GPS2 | 0.715822 | 4 | 0 | 3 |
| RABGAP1 | GUF1 | 0.715258 | 3 | 0 | 3 |
| RABGAP1 | RABL3 | 0.715255 | 4 | 0 | 4 |
| RABGAP1 | ANAPC16 | 0.712876 | 4 | 0 | 4 |
| RABGAP1 | NR2C2 | 0.71211 | 3 | 0 | 3 |
| RABGAP1 | PTAR1 | 0.708666 | 5 | 0 | 5 |
| RABGAP1 | ALKBH8 | 0.708493 | 3 | 0 | 3 |
| RABGAP1 | UBE3B | 0.704221 | 3 | 0 | 3 |
| RABGAP1 | SLC25A23 | 0.699286 | 5 | 0 | 5 |
For details and further investigation, click here
