| Full name: ADP-ribosylhydrolase like 1 | Alias Symbol: ARH2 | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 113622 | HGNC ID: HGNC:21303 | Ensembl Gene: ENSG00000153531 | OMIM ID: 610620 |
| Drug and gene relationship at DGIdb | |||
Expression of ADPRHL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADPRHL1 | 113622 | 238054_at | -0.0344 | 0.9296 | |
| GSE26886 | ADPRHL1 | 113622 | 238054_at | 0.3913 | 0.0194 | |
| GSE45670 | ADPRHL1 | 113622 | 238054_at | 0.0088 | 0.9553 | |
| GSE53622 | ADPRHL1 | 113622 | 8884 | -0.1527 | 0.4590 | |
| GSE53624 | ADPRHL1 | 113622 | 8884 | 0.3340 | 0.0152 | |
| GSE63941 | ADPRHL1 | 113622 | 238054_at | 0.3747 | 0.3698 | |
| GSE77861 | ADPRHL1 | 113622 | 238054_at | 0.0326 | 0.8016 | |
| GSE97050 | ADPRHL1 | 113622 | A_23_P371145 | -0.5576 | 0.1670 | |
| SRP133303 | ADPRHL1 | 113622 | RNAseq | 0.1291 | 0.7875 | |
| SRP159526 | ADPRHL1 | 113622 | RNAseq | 0.8570 | 0.1028 | |
| SRP193095 | ADPRHL1 | 113622 | RNAseq | -0.1989 | 0.2503 | |
| SRP219564 | ADPRHL1 | 113622 | RNAseq | 0.3838 | 0.4991 | |
| TCGA | ADPRHL1 | 113622 | RNAseq | -0.3983 | 0.0371 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADPRHL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADPRHL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADPRHL1 | 113622 | 7 | 12 | 11 | |
| GSE20123 | ADPRHL1 | 113622 | 7 | 11 | 12 | |
| GSE43470 | ADPRHL1 | 113622 | 4 | 13 | 26 | |
| GSE46452 | ADPRHL1 | 113622 | 3 | 31 | 25 | |
| GSE47630 | ADPRHL1 | 113622 | 3 | 26 | 11 | |
| GSE54993 | ADPRHL1 | 113622 | 11 | 4 | 55 | |
| GSE54994 | ADPRHL1 | 113622 | 9 | 10 | 34 | |
| GSE60625 | ADPRHL1 | 113622 | 0 | 3 | 8 | |
| GSE74703 | ADPRHL1 | 113622 | 3 | 10 | 23 | |
| GSE74704 | ADPRHL1 | 113622 | 4 | 9 | 7 | |
| TCGA | ADPRHL1 | 113622 | 21 | 31 | 44 |
Total number of gains: 72; Total number of losses: 160; Total Number of normals: 256.
Somatic mutations of ADPRHL1:
Generating mutation plots.
Highly correlated genes for ADPRHL1:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADPRHL1 | CLMN | 0.703619 | 3 | 0 | 3 |
| ADPRHL1 | RBM41 | 0.695723 | 3 | 0 | 3 |
| ADPRHL1 | COL28A1 | 0.685947 | 3 | 0 | 3 |
| ADPRHL1 | GAA | 0.685459 | 3 | 0 | 3 |
| ADPRHL1 | AVIL | 0.671131 | 3 | 0 | 3 |
| ADPRHL1 | BCL9L | 0.661055 | 3 | 0 | 3 |
| ADPRHL1 | CCNB1IP1 | 0.659238 | 3 | 0 | 3 |
| ADPRHL1 | RBPJ | 0.650566 | 3 | 0 | 3 |
| ADPRHL1 | LRRC39 | 0.649703 | 3 | 0 | 3 |
| ADPRHL1 | TMEM65 | 0.637813 | 4 | 0 | 4 |
| ADPRHL1 | PHPT1 | 0.632193 | 3 | 0 | 3 |
| ADPRHL1 | DNAJC27 | 0.62475 | 4 | 0 | 3 |
| ADPRHL1 | NGDN | 0.62198 | 3 | 0 | 3 |
| ADPRHL1 | LYAR | 0.619945 | 3 | 0 | 3 |
| ADPRHL1 | ISM2 | 0.615155 | 4 | 0 | 3 |
| ADPRHL1 | PARP2 | 0.609035 | 3 | 0 | 3 |
| ADPRHL1 | CA3 | 0.608384 | 3 | 0 | 3 |
| ADPRHL1 | REC8 | 0.607941 | 3 | 0 | 3 |
| ADPRHL1 | PAK1 | 0.604731 | 4 | 0 | 3 |
| ADPRHL1 | SP4 | 0.59683 | 4 | 0 | 3 |
For details and further investigation, click here
