| Full name: LYR motif containing 2 | Alias Symbol: DJ122O8.2 | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 57226 | HGNC ID: HGNC:25229 | Ensembl Gene: ENSG00000083099 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LYRM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYRM2 | 57226 | 227712_at | -0.4584 | 0.4155 | |
| GSE20347 | LYRM2 | 57226 | 221311_x_at | 0.1318 | 0.4765 | |
| GSE23400 | LYRM2 | 57226 | 221311_x_at | 0.2765 | 0.0000 | |
| GSE26886 | LYRM2 | 57226 | 227797_x_at | -0.0904 | 0.4222 | |
| GSE29001 | LYRM2 | 57226 | 221311_x_at | 0.4631 | 0.0647 | |
| GSE38129 | LYRM2 | 57226 | 221311_x_at | 0.2782 | 0.0507 | |
| GSE45670 | LYRM2 | 57226 | 227712_at | 0.2050 | 0.0834 | |
| GSE53622 | LYRM2 | 57226 | 54679 | 0.2186 | 0.0002 | |
| GSE53624 | LYRM2 | 57226 | 54679 | 0.3657 | 0.0000 | |
| GSE63941 | LYRM2 | 57226 | 221311_x_at | 0.3850 | 0.2968 | |
| GSE77861 | LYRM2 | 57226 | 227712_at | 0.3067 | 0.2309 | |
| GSE97050 | LYRM2 | 57226 | A_23_P42042 | 0.0077 | 0.9808 | |
| SRP007169 | LYRM2 | 57226 | RNAseq | 1.8236 | 0.0001 | |
| SRP008496 | LYRM2 | 57226 | RNAseq | 1.7146 | 0.0000 | |
| SRP064894 | LYRM2 | 57226 | RNAseq | 0.2120 | 0.1253 | |
| SRP133303 | LYRM2 | 57226 | RNAseq | 0.1801 | 0.1370 | |
| SRP159526 | LYRM2 | 57226 | RNAseq | 0.2960 | 0.0813 | |
| SRP193095 | LYRM2 | 57226 | RNAseq | -0.1481 | 0.0650 | |
| SRP219564 | LYRM2 | 57226 | RNAseq | -0.1247 | 0.6959 | |
| TCGA | LYRM2 | 57226 | RNAseq | -0.0440 | 0.3911 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LYRM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYRM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYRM2 | 57226 | 1 | 4 | 25 | |
| GSE20123 | LYRM2 | 57226 | 1 | 3 | 26 | |
| GSE43470 | LYRM2 | 57226 | 2 | 1 | 40 | |
| GSE46452 | LYRM2 | 57226 | 2 | 11 | 46 | |
| GSE47630 | LYRM2 | 57226 | 8 | 6 | 26 | |
| GSE54993 | LYRM2 | 57226 | 3 | 2 | 65 | |
| GSE54994 | LYRM2 | 57226 | 8 | 8 | 37 | |
| GSE60625 | LYRM2 | 57226 | 0 | 1 | 10 | |
| GSE74703 | LYRM2 | 57226 | 2 | 1 | 33 | |
| GSE74704 | LYRM2 | 57226 | 0 | 2 | 18 | |
| TCGA | LYRM2 | 57226 | 6 | 21 | 69 |
Total number of gains: 33; Total number of losses: 60; Total Number of normals: 395.
Somatic mutations of LYRM2:
Generating mutation plots.
Highly correlated genes for LYRM2:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYRM2 | C2orf68 | 0.748195 | 3 | 0 | 3 |
| LYRM2 | TMEM218 | 0.733808 | 3 | 0 | 3 |
| LYRM2 | CEP44 | 0.713017 | 3 | 0 | 3 |
| LYRM2 | PAPSS2 | 0.698038 | 3 | 0 | 3 |
| LYRM2 | TRPM7 | 0.689251 | 3 | 0 | 3 |
| LYRM2 | GNG10 | 0.68541 | 3 | 0 | 3 |
| LYRM2 | NAA15 | 0.671355 | 5 | 0 | 4 |
| LYRM2 | NCBP1 | 0.669723 | 6 | 0 | 5 |
| LYRM2 | SLC5A3 | 0.668182 | 4 | 0 | 3 |
| LYRM2 | SLC25A3 | 0.667526 | 3 | 0 | 3 |
| LYRM2 | TIPRL | 0.666618 | 3 | 0 | 3 |
| LYRM2 | LATS1 | 0.663895 | 4 | 0 | 3 |
| LYRM2 | NEDD8 | 0.661517 | 4 | 0 | 3 |
| LYRM2 | GMPR2 | 0.659864 | 5 | 0 | 4 |
| LYRM2 | GTF2A2 | 0.657069 | 5 | 0 | 5 |
| LYRM2 | UBXN2A | 0.647536 | 4 | 0 | 3 |
| LYRM2 | LAP3 | 0.647279 | 4 | 0 | 3 |
| LYRM2 | THUMPD1 | 0.644212 | 4 | 0 | 3 |
| LYRM2 | TMEM38B | 0.641551 | 8 | 0 | 6 |
| LYRM2 | IMPACT | 0.640283 | 5 | 0 | 4 |
For details and further investigation, click here
