| Full name: mitogen-activated protein kinase binding protein 1 | Alias Symbol: KIAA0596|NPHP20 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 23005 | HGNC ID: HGNC:29536 | Ensembl Gene: ENSG00000137802 | OMIM ID: 616786 |
| Drug and gene relationship at DGIdb | |||
Expression of MAPKBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAPKBP1 | 23005 | 213394_at | -0.0274 | 0.9779 | |
| GSE20347 | MAPKBP1 | 23005 | 213394_at | -0.1414 | 0.3288 | |
| GSE23400 | MAPKBP1 | 23005 | 213394_at | -0.2614 | 0.0000 | |
| GSE26886 | MAPKBP1 | 23005 | 213394_at | -0.0742 | 0.6848 | |
| GSE29001 | MAPKBP1 | 23005 | 213394_at | -0.4066 | 0.1779 | |
| GSE38129 | MAPKBP1 | 23005 | 213394_at | -0.1936 | 0.1870 | |
| GSE45670 | MAPKBP1 | 23005 | 213394_at | 0.1018 | 0.5788 | |
| GSE53622 | MAPKBP1 | 23005 | 88405 | -0.2950 | 0.0003 | |
| GSE53624 | MAPKBP1 | 23005 | 88405 | -0.2110 | 0.0020 | |
| GSE63941 | MAPKBP1 | 23005 | 213394_at | -0.1646 | 0.7689 | |
| GSE77861 | MAPKBP1 | 23005 | 213394_at | 0.0451 | 0.8827 | |
| GSE97050 | MAPKBP1 | 23005 | A_24_P944444 | -0.5408 | 0.1729 | |
| SRP007169 | MAPKBP1 | 23005 | RNAseq | 0.1173 | 0.7472 | |
| SRP008496 | MAPKBP1 | 23005 | RNAseq | 0.0537 | 0.8474 | |
| SRP064894 | MAPKBP1 | 23005 | RNAseq | -0.5852 | 0.0128 | |
| SRP133303 | MAPKBP1 | 23005 | RNAseq | -0.3766 | 0.0255 | |
| SRP159526 | MAPKBP1 | 23005 | RNAseq | -0.2967 | 0.1713 | |
| SRP193095 | MAPKBP1 | 23005 | RNAseq | 0.1138 | 0.5430 | |
| SRP219564 | MAPKBP1 | 23005 | RNAseq | -0.7672 | 0.0348 | |
| TCGA | MAPKBP1 | 23005 | RNAseq | 0.0884 | 0.1427 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAPKBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAPKBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAPKBP1 | 23005 | 4 | 5 | 21 | |
| GSE20123 | MAPKBP1 | 23005 | 4 | 5 | 21 | |
| GSE43470 | MAPKBP1 | 23005 | 4 | 5 | 34 | |
| GSE46452 | MAPKBP1 | 23005 | 3 | 7 | 49 | |
| GSE47630 | MAPKBP1 | 23005 | 8 | 11 | 21 | |
| GSE54993 | MAPKBP1 | 23005 | 4 | 6 | 60 | |
| GSE54994 | MAPKBP1 | 23005 | 5 | 7 | 41 | |
| GSE60625 | MAPKBP1 | 23005 | 4 | 0 | 7 | |
| GSE74703 | MAPKBP1 | 23005 | 4 | 4 | 28 | |
| GSE74704 | MAPKBP1 | 23005 | 3 | 3 | 14 | |
| TCGA | MAPKBP1 | 23005 | 11 | 18 | 67 |
Total number of gains: 54; Total number of losses: 71; Total Number of normals: 363.
Somatic mutations of MAPKBP1:
Generating mutation plots.
Highly correlated genes for MAPKBP1:
Showing top 20/62 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAPKBP1 | RAB1B | 0.657865 | 4 | 0 | 3 |
| MAPKBP1 | THRA | 0.650198 | 3 | 0 | 3 |
| MAPKBP1 | DMPK | 0.642283 | 3 | 0 | 3 |
| MAPKBP1 | RPAP1 | 0.622722 | 4 | 0 | 3 |
| MAPKBP1 | TMEM222 | 0.609307 | 4 | 0 | 3 |
| MAPKBP1 | BACE1 | 0.608576 | 3 | 0 | 3 |
| MAPKBP1 | PAQR6 | 0.606814 | 4 | 0 | 3 |
| MAPKBP1 | RAB3A | 0.583777 | 4 | 0 | 3 |
| MAPKBP1 | OR11A1 | 0.576692 | 3 | 0 | 3 |
| MAPKBP1 | REEP2 | 0.574504 | 4 | 0 | 3 |
| MAPKBP1 | GSTM2 | 0.573983 | 4 | 0 | 3 |
| MAPKBP1 | USP2 | 0.570927 | 4 | 0 | 3 |
| MAPKBP1 | EPN2 | 0.569567 | 3 | 0 | 3 |
| MAPKBP1 | DAO | 0.569186 | 3 | 0 | 3 |
| MAPKBP1 | AHNAK | 0.56677 | 4 | 0 | 3 |
| MAPKBP1 | STARD5 | 0.564956 | 5 | 0 | 3 |
| MAPKBP1 | ANKS1B | 0.564815 | 5 | 0 | 3 |
| MAPKBP1 | C3orf62 | 0.56279 | 4 | 0 | 3 |
| MAPKBP1 | FEM1B | 0.562719 | 6 | 0 | 5 |
| MAPKBP1 | NKD1 | 0.560601 | 4 | 0 | 3 |
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