| Full name: matrilin 3 | Alias Symbol: EDM5|HOA | ||
| Type: protein-coding gene | Cytoband: 2p24.1 | ||
| Entrez ID: 4148 | HGNC ID: HGNC:6909 | Ensembl Gene: ENSG00000132031 | OMIM ID: 602109 |
| Drug and gene relationship at DGIdb | |||
Expression of MATN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MATN3 | 4148 | 206091_at | 0.5452 | 0.4989 | |
| GSE20347 | MATN3 | 4148 | 206091_at | 0.2883 | 0.0818 | |
| GSE23400 | MATN3 | 4148 | 206091_at | 0.0721 | 0.0000 | |
| GSE26886 | MATN3 | 4148 | 206091_at | 0.3292 | 0.0288 | |
| GSE29001 | MATN3 | 4148 | 206091_at | 0.2619 | 0.0171 | |
| GSE38129 | MATN3 | 4148 | 206091_at | 0.4494 | 0.0006 | |
| GSE45670 | MATN3 | 4148 | 206091_at | 0.2364 | 0.2856 | |
| GSE53622 | MATN3 | 4148 | 27679 | 1.7126 | 0.0000 | |
| GSE53624 | MATN3 | 4148 | 27679 | 1.8920 | 0.0000 | |
| GSE63941 | MATN3 | 4148 | 206091_at | -0.9001 | 0.0523 | |
| GSE77861 | MATN3 | 4148 | 206091_at | 0.1270 | 0.2944 | |
| GSE97050 | MATN3 | 4148 | A_33_P3420466 | 0.6214 | 0.2151 | |
| SRP007169 | MATN3 | 4148 | RNAseq | 5.1879 | 0.0004 | |
| SRP133303 | MATN3 | 4148 | RNAseq | 2.3647 | 0.0000 | |
| SRP159526 | MATN3 | 4148 | RNAseq | 0.6726 | 0.1644 | |
| SRP219564 | MATN3 | 4148 | RNAseq | 1.0089 | 0.0393 | |
| TCGA | MATN3 | 4148 | RNAseq | 0.5555 | 0.0184 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by MATN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MATN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MATN3 | 4148 | 9 | 2 | 19 | |
| GSE20123 | MATN3 | 4148 | 9 | 2 | 19 | |
| GSE43470 | MATN3 | 4148 | 2 | 0 | 41 | |
| GSE46452 | MATN3 | 4148 | 3 | 4 | 52 | |
| GSE47630 | MATN3 | 4148 | 7 | 0 | 33 | |
| GSE54993 | MATN3 | 4148 | 0 | 7 | 63 | |
| GSE54994 | MATN3 | 4148 | 11 | 0 | 42 | |
| GSE60625 | MATN3 | 4148 | 0 | 3 | 8 | |
| GSE74703 | MATN3 | 4148 | 2 | 0 | 34 | |
| GSE74704 | MATN3 | 4148 | 8 | 2 | 10 | |
| TCGA | MATN3 | 4148 | 37 | 2 | 57 |
Total number of gains: 88; Total number of losses: 22; Total Number of normals: 378.
Somatic mutations of MATN3:
Generating mutation plots.
Highly correlated genes for MATN3:
Showing top 20/517 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MATN3 | ZNF511 | 0.685629 | 3 | 0 | 3 |
| MATN3 | LHX2 | 0.674471 | 4 | 0 | 4 |
| MATN3 | OSBPL3 | 0.667301 | 3 | 0 | 3 |
| MATN3 | C1QTNF6 | 0.661185 | 4 | 0 | 3 |
| MATN3 | SPATA5 | 0.660773 | 3 | 0 | 3 |
| MATN3 | SLC6A15 | 0.660063 | 5 | 0 | 4 |
| MATN3 | TUBAL3 | 0.657956 | 3 | 0 | 3 |
| MATN3 | TRHDE | 0.657465 | 3 | 0 | 3 |
| MATN3 | SPRY4-IT1 | 0.656614 | 4 | 0 | 3 |
| MATN3 | CST1 | 0.653174 | 7 | 0 | 7 |
| MATN3 | FANCB | 0.652807 | 4 | 0 | 3 |
| MATN3 | CCBE1 | 0.649842 | 3 | 0 | 3 |
| MATN3 | PTX3 | 0.646744 | 4 | 0 | 3 |
| MATN3 | DLX1 | 0.640519 | 3 | 0 | 3 |
| MATN3 | RAD54L | 0.63902 | 4 | 0 | 3 |
| MATN3 | FANCM | 0.635477 | 4 | 0 | 3 |
| MATN3 | CHPF | 0.62711 | 7 | 0 | 6 |
| MATN3 | ZRANB3 | 0.626782 | 6 | 0 | 4 |
| MATN3 | HOXA11 | 0.626032 | 3 | 0 | 3 |
| MATN3 | TMEM200A | 0.624932 | 4 | 0 | 4 |
For details and further investigation, click here
