| Full name: muscleblind like splicing regulator 2 | Alias Symbol: MBLL|MBLL39 | ||
| Type: protein-coding gene | Cytoband: 13q32.1 | ||
| Entrez ID: 10150 | HGNC ID: HGNC:16746 | Ensembl Gene: ENSG00000139793 | OMIM ID: 607327 |
| Drug and gene relationship at DGIdb | |||
Expression of MBNL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBNL2 | 10150 | 203640_at | -0.7398 | 0.1182 | |
| GSE20347 | MBNL2 | 10150 | 203640_at | -0.1848 | 0.3804 | |
| GSE23400 | MBNL2 | 10150 | 203640_at | 0.0927 | 0.4873 | |
| GSE26886 | MBNL2 | 10150 | 203640_at | 0.7615 | 0.0106 | |
| GSE29001 | MBNL2 | 10150 | 203640_at | -0.2046 | 0.6803 | |
| GSE38129 | MBNL2 | 10150 | 203640_at | -0.4388 | 0.0153 | |
| GSE45670 | MBNL2 | 10150 | 203640_at | -0.4317 | 0.0619 | |
| GSE53622 | MBNL2 | 10150 | 133994 | -0.1066 | 0.3314 | |
| GSE53624 | MBNL2 | 10150 | 54529 | -0.4405 | 0.0000 | |
| GSE63941 | MBNL2 | 10150 | 203640_at | -1.0964 | 0.0827 | |
| GSE77861 | MBNL2 | 10150 | 203640_at | 0.2796 | 0.4614 | |
| GSE97050 | MBNL2 | 10150 | A_33_P3391076 | 0.0554 | 0.8248 | |
| SRP007169 | MBNL2 | 10150 | RNAseq | 0.2129 | 0.5892 | |
| SRP008496 | MBNL2 | 10150 | RNAseq | 0.6173 | 0.0145 | |
| SRP064894 | MBNL2 | 10150 | RNAseq | -0.0761 | 0.7541 | |
| SRP133303 | MBNL2 | 10150 | RNAseq | 0.0240 | 0.8752 | |
| SRP159526 | MBNL2 | 10150 | RNAseq | -0.7209 | 0.0037 | |
| SRP193095 | MBNL2 | 10150 | RNAseq | -0.1131 | 0.4810 | |
| SRP219564 | MBNL2 | 10150 | RNAseq | -0.2621 | 0.6069 | |
| TCGA | MBNL2 | 10150 | RNAseq | -0.2185 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MBNL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MBNL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MBNL2 | 10150 | 4 | 9 | 17 | |
| GSE20123 | MBNL2 | 10150 | 4 | 8 | 18 | |
| GSE43470 | MBNL2 | 10150 | 4 | 12 | 27 | |
| GSE46452 | MBNL2 | 10150 | 0 | 32 | 27 | |
| GSE47630 | MBNL2 | 10150 | 3 | 26 | 11 | |
| GSE54993 | MBNL2 | 10150 | 11 | 3 | 56 | |
| GSE54994 | MBNL2 | 10150 | 3 | 13 | 37 | |
| GSE60625 | MBNL2 | 10150 | 0 | 3 | 8 | |
| GSE74703 | MBNL2 | 10150 | 3 | 10 | 23 | |
| GSE74704 | MBNL2 | 10150 | 2 | 8 | 10 | |
| TCGA | MBNL2 | 10150 | 14 | 34 | 48 |
Total number of gains: 48; Total number of losses: 158; Total Number of normals: 282.
Somatic mutations of MBNL2:
Generating mutation plots.
Highly correlated genes for MBNL2:
Showing top 20/602 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBNL2 | TGFBR1 | 0.772728 | 3 | 0 | 3 |
| MBNL2 | RASSF3 | 0.730051 | 4 | 0 | 4 |
| MBNL2 | ATP11C | 0.72598 | 3 | 0 | 3 |
| MBNL2 | PMPCB | 0.716313 | 3 | 0 | 3 |
| MBNL2 | IGFBP3 | 0.7118 | 3 | 0 | 3 |
| MBNL2 | SLC44A1 | 0.708948 | 3 | 0 | 3 |
| MBNL2 | NSRP1 | 0.698677 | 3 | 0 | 3 |
| MBNL2 | LYRM7 | 0.698583 | 3 | 0 | 3 |
| MBNL2 | CCNB1IP1 | 0.692993 | 3 | 0 | 3 |
| MBNL2 | SOCS4 | 0.690077 | 3 | 0 | 3 |
| MBNL2 | EIF5A2 | 0.683552 | 3 | 0 | 3 |
| MBNL2 | SGTB | 0.674967 | 5 | 0 | 5 |
| MBNL2 | TCEAL3 | 0.674774 | 3 | 0 | 3 |
| MBNL2 | HIP1 | 0.671913 | 3 | 0 | 3 |
| MBNL2 | TCEA1 | 0.669808 | 3 | 0 | 3 |
| MBNL2 | FAM98B | 0.669435 | 3 | 0 | 3 |
| MBNL2 | ANO6 | 0.667865 | 8 | 0 | 6 |
| MBNL2 | DENND6A | 0.66651 | 3 | 0 | 3 |
| MBNL2 | CEP63 | 0.664924 | 3 | 0 | 3 |
| MBNL2 | ANAPC4 | 0.663606 | 3 | 0 | 3 |
For details and further investigation, click here
