| Full name: mesenchyme homeobox 1 | Alias Symbol: MOX1 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 4222 | HGNC ID: HGNC:7013 | Ensembl Gene: ENSG00000005102 | OMIM ID: 600147 |
| Drug and gene relationship at DGIdb | |||
Expression of MEOX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEOX1 | 4222 | 205619_s_at | -0.4339 | 0.3489 | |
| GSE20347 | MEOX1 | 4222 | 205619_s_at | -0.0555 | 0.7299 | |
| GSE23400 | MEOX1 | 4222 | 205619_s_at | -0.0828 | 0.3069 | |
| GSE26886 | MEOX1 | 4222 | 205619_s_at | -0.2371 | 0.4156 | |
| GSE29001 | MEOX1 | 4222 | 205619_s_at | -0.1664 | 0.7210 | |
| GSE38129 | MEOX1 | 4222 | 205619_s_at | -0.2793 | 0.3425 | |
| GSE45670 | MEOX1 | 4222 | 205619_s_at | -0.3734 | 0.4004 | |
| GSE53622 | MEOX1 | 4222 | 74972 | -1.1324 | 0.0000 | |
| GSE53624 | MEOX1 | 4222 | 74972 | -0.7519 | 0.0000 | |
| GSE63941 | MEOX1 | 4222 | 205619_s_at | 0.4840 | 0.6361 | |
| GSE77861 | MEOX1 | 4222 | 205619_s_at | 0.1064 | 0.5009 | |
| SRP007169 | MEOX1 | 4222 | RNAseq | 2.2882 | 0.0232 | |
| SRP064894 | MEOX1 | 4222 | RNAseq | 0.0447 | 0.8961 | |
| SRP133303 | MEOX1 | 4222 | RNAseq | -1.1987 | 0.0008 | |
| SRP159526 | MEOX1 | 4222 | RNAseq | 0.3810 | 0.4891 | |
| SRP219564 | MEOX1 | 4222 | RNAseq | -0.3785 | 0.7213 | |
| TCGA | MEOX1 | 4222 | RNAseq | -0.3104 | 0.2845 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by MEOX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEOX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEOX1 | 4222 | 5 | 2 | 23 | |
| GSE20123 | MEOX1 | 4222 | 5 | 2 | 23 | |
| GSE43470 | MEOX1 | 4222 | 1 | 2 | 40 | |
| GSE46452 | MEOX1 | 4222 | 32 | 0 | 27 | |
| GSE47630 | MEOX1 | 4222 | 8 | 1 | 31 | |
| GSE54993 | MEOX1 | 4222 | 3 | 4 | 63 | |
| GSE54994 | MEOX1 | 4222 | 8 | 6 | 39 | |
| GSE60625 | MEOX1 | 4222 | 4 | 0 | 7 | |
| GSE74703 | MEOX1 | 4222 | 1 | 1 | 34 | |
| GSE74704 | MEOX1 | 4222 | 3 | 1 | 16 | |
| TCGA | MEOX1 | 4222 | 24 | 6 | 66 |
Total number of gains: 94; Total number of losses: 25; Total Number of normals: 369.
Somatic mutations of MEOX1:
Generating mutation plots.
Highly correlated genes for MEOX1:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEOX1 | EMCN | 0.698332 | 4 | 0 | 3 |
| MEOX1 | PHF1 | 0.661412 | 3 | 0 | 3 |
| MEOX1 | TEK | 0.660981 | 6 | 0 | 4 |
| MEOX1 | TSPAN18 | 0.659126 | 3 | 0 | 3 |
| MEOX1 | A2M | 0.656086 | 7 | 0 | 6 |
| MEOX1 | VWF | 0.653261 | 7 | 0 | 6 |
| MEOX1 | GLT8D2 | 0.649943 | 3 | 0 | 3 |
| MEOX1 | PDGFRB | 0.642216 | 3 | 0 | 3 |
| MEOX1 | COL15A1 | 0.640335 | 6 | 0 | 5 |
| MEOX1 | PRKAG2 | 0.64009 | 3 | 0 | 3 |
| MEOX1 | CLEC1A | 0.639825 | 4 | 0 | 4 |
| MEOX1 | DCHS1 | 0.632331 | 5 | 0 | 4 |
| MEOX1 | RNF14 | 0.630945 | 3 | 0 | 3 |
| MEOX1 | VASH1 | 0.630408 | 3 | 0 | 3 |
| MEOX1 | XPNPEP2 | 0.629192 | 4 | 0 | 4 |
| MEOX1 | RAMP3 | 0.625893 | 8 | 0 | 6 |
| MEOX1 | EPS8 | 0.624826 | 4 | 0 | 3 |
| MEOX1 | PCOLCE | 0.623582 | 3 | 0 | 3 |
| MEOX1 | FAT4 | 0.622767 | 5 | 0 | 4 |
| MEOX1 | TRPA1 | 0.620838 | 4 | 0 | 3 |
For details and further investigation, click here
