| Full name: microsomal glutathione S-transferase 3 | Alias Symbol: GST-III | ||
| Type: protein-coding gene | Cytoband: 1q24.1 | ||
| Entrez ID: 4259 | HGNC ID: HGNC:7064 | Ensembl Gene: ENSG00000143198 | OMIM ID: 604564 |
| Drug and gene relationship at DGIdb | |||
Expression of MGST3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MGST3 | 4259 | 201403_s_at | -0.1930 | 0.5670 | |
| GSE20347 | MGST3 | 4259 | 201403_s_at | -0.4325 | 0.0862 | |
| GSE23400 | MGST3 | 4259 | 201403_s_at | -0.0846 | 0.3358 | |
| GSE26886 | MGST3 | 4259 | 201403_s_at | 0.2795 | 0.3331 | |
| GSE29001 | MGST3 | 4259 | 201403_s_at | -0.4142 | 0.3338 | |
| GSE38129 | MGST3 | 4259 | 201403_s_at | -0.4601 | 0.0256 | |
| GSE45670 | MGST3 | 4259 | 201403_s_at | -0.4848 | 0.0035 | |
| GSE53622 | MGST3 | 4259 | 48269 | -0.3365 | 0.0001 | |
| GSE53624 | MGST3 | 4259 | 48269 | -0.1721 | 0.0101 | |
| GSE63941 | MGST3 | 4259 | 201403_s_at | -0.7966 | 0.1527 | |
| GSE77861 | MGST3 | 4259 | 201403_s_at | 0.1380 | 0.4954 | |
| GSE97050 | MGST3 | 4259 | A_23_P51548 | -0.6965 | 0.1186 | |
| SRP007169 | MGST3 | 4259 | RNAseq | -0.8724 | 0.0462 | |
| SRP008496 | MGST3 | 4259 | RNAseq | -0.2969 | 0.2872 | |
| SRP064894 | MGST3 | 4259 | RNAseq | 0.1556 | 0.5657 | |
| SRP133303 | MGST3 | 4259 | RNAseq | -0.0659 | 0.6938 | |
| SRP159526 | MGST3 | 4259 | RNAseq | 0.0223 | 0.9378 | |
| SRP193095 | MGST3 | 4259 | RNAseq | -1.0040 | 0.0001 | |
| SRP219564 | MGST3 | 4259 | RNAseq | -0.2052 | 0.6784 | |
| TCGA | MGST3 | 4259 | RNAseq | -0.1586 | 0.0054 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MGST3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MGST3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MGST3 | 4259 | 10 | 2 | 18 | |
| GSE20123 | MGST3 | 4259 | 10 | 2 | 18 | |
| GSE43470 | MGST3 | 4259 | 7 | 2 | 34 | |
| GSE46452 | MGST3 | 4259 | 2 | 1 | 56 | |
| GSE47630 | MGST3 | 4259 | 14 | 0 | 26 | |
| GSE54993 | MGST3 | 4259 | 0 | 5 | 65 | |
| GSE54994 | MGST3 | 4259 | 16 | 0 | 37 | |
| GSE60625 | MGST3 | 4259 | 0 | 0 | 11 | |
| GSE74703 | MGST3 | 4259 | 7 | 2 | 27 | |
| GSE74704 | MGST3 | 4259 | 4 | 1 | 15 | |
| TCGA | MGST3 | 4259 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 18; Total Number of normals: 356.
Somatic mutations of MGST3:
Generating mutation plots.
Highly correlated genes for MGST3:
Showing top 20/427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MGST3 | PNCK | 0.720348 | 3 | 0 | 3 |
| MGST3 | MYL6 | 0.696294 | 7 | 0 | 6 |
| MGST3 | PPP1R14A | 0.684898 | 4 | 0 | 3 |
| MGST3 | DMPK | 0.675048 | 4 | 0 | 4 |
| MGST3 | GLB1L2 | 0.670697 | 3 | 0 | 3 |
| MGST3 | PLP1 | 0.659186 | 5 | 0 | 5 |
| MGST3 | COX20 | 0.658142 | 4 | 0 | 3 |
| MGST3 | THRB | 0.656549 | 5 | 0 | 4 |
| MGST3 | CAMK2G | 0.650188 | 5 | 0 | 5 |
| MGST3 | SLMAP | 0.646273 | 4 | 0 | 3 |
| MGST3 | RBPMS2 | 0.645515 | 4 | 0 | 3 |
| MGST3 | FXYD1 | 0.637839 | 5 | 0 | 4 |
| MGST3 | FILIP1 | 0.619786 | 5 | 0 | 4 |
| MGST3 | PYGM | 0.61977 | 6 | 0 | 4 |
| MGST3 | LDB3 | 0.61771 | 4 | 0 | 3 |
| MGST3 | COX6C | 0.615514 | 4 | 0 | 3 |
| MGST3 | C1QTNF7 | 0.613782 | 5 | 0 | 3 |
| MGST3 | LAMB2 | 0.613465 | 8 | 0 | 6 |
| MGST3 | STK33 | 0.613092 | 4 | 0 | 3 |
| MGST3 | CCDC136 | 0.612859 | 4 | 0 | 3 |
For details and further investigation, click here
