C12orf75

 

Full name: chromosome 12 open reading frame 75 Alias Symbol: OCC-1|OCC1|AGD3
Type: protein-coding gene Cytoband: 12q23.3
Entrez ID: 387882 HGNC ID: HGNC:35164 Ensembl Gene: ENSG00000235162 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C12orf75:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C12orf75 387882 225105_at 1.1374 0.4803
GSE26886 C12orf75 387882 225105_at 2.8909 0.0000
GSE45670 C12orf75 387882 225105_at 1.6080 0.0001
GSE53622 C12orf75 387882 62011 1.7074 0.0000
GSE53624 C12orf75 387882 62011 1.8133 0.0000
GSE63941 C12orf75 387882 225105_at -2.3146 0.0190
GSE77861 C12orf75 387882 225105_at 1.8654 0.0082
GSE97050 C12orf75 387882 A_32_P163089 1.2881 0.1049
SRP007169 C12orf75 387882 RNAseq 2.5755 0.0001
SRP008496 C12orf75 387882 RNAseq 2.7893 0.0000
SRP064894 C12orf75 387882 RNAseq 1.8134 0.0000
SRP133303 C12orf75 387882 RNAseq 1.5274 0.0001
SRP159526 C12orf75 387882 RNAseq 1.8997 0.0006
SRP193095 C12orf75 387882 RNAseq 0.9981 0.0015
SRP219564 C12orf75 387882 RNAseq 0.4407 0.4708
TCGA C12orf75 387882 RNAseq 0.0643 0.6548

Upregulated datasets: 10; Downregulated datasets: 1.  

 

Survival by C12orf75 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C12orf75:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C12orf75 387882 4 2 24
GSE20123 C12orf75 387882 5 2 23
GSE43470 C12orf75 387882 2 0 41
GSE46452 C12orf75 387882 9 1 49
GSE47630 C12orf75 387882 9 1 30
GSE54993 C12orf75 387882 0 5 65
GSE54994 C12orf75 387882 4 2 47
GSE60625 C12orf75 387882 0 0 11
GSE74703 C12orf75 387882 2 0 34
GSE74704 C12orf75 387882 2 2 16
TCGA C12orf75 387882 19 10 67

Total number of gains: 56; Total number of losses: 25; Total Number of normals: 407.  

 

Somatic mutations of C12orf75:

 

Generating mutation plots.

 

Highly correlated genes for C12orf75:

 

Showing top 20/1463 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C12orf75OSR20.817351303
C12orf75MET0.80742707
C12orf75RHOQ0.791358303
C12orf75EML40.766759404
C12orf75LRRK10.764573303
C12orf75FAM89A0.760584303
C12orf75ARPC1B0.753905707
C12orf75MTERF30.753581303
C12orf75DNMT10.752548606
C12orf75LRRC8D0.748941707
C12orf75ADCY30.747352404
C12orf75IRX40.745441303
C12orf75ACTL6A0.744953606
C12orf75RGS10.74315303
C12orf75ZNF2810.742895707
C12orf75IFITM10.739395404
C12orf75PARP120.739258606
C12orf75MYO5A0.73861808
C12orf75ADA0.735697707
C12orf75SLC44A10.732882707

For details and further investigation, click here