| Full name: ubiquitin specific peptidase 13 | Alias Symbol: IsoT-3 | ||
| Type: protein-coding gene | Cytoband: 3q26.33 | ||
| Entrez ID: 8975 | HGNC ID: HGNC:12611 | Ensembl Gene: ENSG00000058056 | OMIM ID: 603591 |
| Drug and gene relationship at DGIdb | |||
Expression of USP13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP13 | 8975 | 205356_at | 0.2817 | 0.4812 | |
| GSE20347 | USP13 | 8975 | 205356_at | 0.7153 | 0.0005 | |
| GSE23400 | USP13 | 8975 | 205356_at | 0.2591 | 0.0011 | |
| GSE26886 | USP13 | 8975 | 205356_at | 0.7492 | 0.0320 | |
| GSE29001 | USP13 | 8975 | 205356_at | 0.5895 | 0.1102 | |
| GSE38129 | USP13 | 8975 | 205356_at | 0.4770 | 0.0121 | |
| GSE45670 | USP13 | 8975 | 205356_at | 0.0749 | 0.8626 | |
| GSE53622 | USP13 | 8975 | 26050 | 0.6429 | 0.0000 | |
| GSE53624 | USP13 | 8975 | 26050 | 0.7758 | 0.0000 | |
| GSE63941 | USP13 | 8975 | 205356_at | 1.2237 | 0.0808 | |
| GSE77861 | USP13 | 8975 | 227788_at | -0.2155 | 0.1076 | |
| GSE97050 | USP13 | 8975 | A_23_P40989 | -0.0189 | 0.9706 | |
| SRP007169 | USP13 | 8975 | RNAseq | 2.2144 | 0.0002 | |
| SRP008496 | USP13 | 8975 | RNAseq | 1.5549 | 0.0002 | |
| SRP064894 | USP13 | 8975 | RNAseq | 0.4169 | 0.0429 | |
| SRP133303 | USP13 | 8975 | RNAseq | 0.8281 | 0.0080 | |
| SRP159526 | USP13 | 8975 | RNAseq | 1.3847 | 0.0003 | |
| SRP193095 | USP13 | 8975 | RNAseq | 0.8742 | 0.0000 | |
| SRP219564 | USP13 | 8975 | RNAseq | -0.0787 | 0.8830 | |
| TCGA | USP13 | 8975 | RNAseq | 0.1402 | 0.1528 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by USP13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP13 | 8975 | 25 | 0 | 5 | |
| GSE20123 | USP13 | 8975 | 25 | 0 | 5 | |
| GSE43470 | USP13 | 8975 | 24 | 0 | 19 | |
| GSE46452 | USP13 | 8975 | 19 | 1 | 39 | |
| GSE47630 | USP13 | 8975 | 27 | 2 | 11 | |
| GSE54993 | USP13 | 8975 | 1 | 18 | 51 | |
| GSE54994 | USP13 | 8975 | 41 | 0 | 12 | |
| GSE60625 | USP13 | 8975 | 0 | 6 | 5 | |
| GSE74703 | USP13 | 8975 | 20 | 0 | 16 | |
| GSE74704 | USP13 | 8975 | 16 | 0 | 4 | |
| TCGA | USP13 | 8975 | 78 | 0 | 18 |
Total number of gains: 276; Total number of losses: 27; Total Number of normals: 185.
Somatic mutations of USP13:
Generating mutation plots.
Highly correlated genes for USP13:
Showing top 20/310 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP13 | MICU1 | 0.773312 | 3 | 0 | 3 |
| USP13 | TMEM25 | 0.75386 | 3 | 0 | 3 |
| USP13 | LRTOMT | 0.730071 | 4 | 0 | 3 |
| USP13 | METAP1D | 0.725904 | 3 | 0 | 3 |
| USP13 | HERC2 | 0.72441 | 3 | 0 | 3 |
| USP13 | GHDC | 0.723971 | 3 | 0 | 3 |
| USP13 | TIMM23 | 0.718553 | 3 | 0 | 3 |
| USP13 | ZNF354C | 0.714829 | 3 | 0 | 3 |
| USP13 | B4GALNT4 | 0.701881 | 3 | 0 | 3 |
| USP13 | MRPL35 | 0.698602 | 3 | 0 | 3 |
| USP13 | ABHD2 | 0.694 | 4 | 0 | 4 |
| USP13 | UBE3A | 0.693872 | 3 | 0 | 3 |
| USP13 | ZDHHC16 | 0.684889 | 3 | 0 | 3 |
| USP13 | DGKH | 0.684151 | 3 | 0 | 3 |
| USP13 | LRP6 | 0.682252 | 9 | 0 | 8 |
| USP13 | SFT2D3 | 0.673774 | 4 | 0 | 3 |
| USP13 | DAZAP1 | 0.667584 | 3 | 0 | 3 |
| USP13 | PCGF6 | 0.66552 | 4 | 0 | 3 |
| USP13 | RAB34 | 0.661656 | 3 | 0 | 3 |
| USP13 | PIP5K1B | 0.659875 | 5 | 0 | 5 |
For details and further investigation, click here
