| Full name: melan-A | Alias Symbol: MART1 | ||
| Type: protein-coding gene | Cytoband: 9p24.1 | ||
| Entrez ID: 2315 | HGNC ID: HGNC:7124 | Ensembl Gene: ENSG00000120215 | OMIM ID: 605513 |
| Drug and gene relationship at DGIdb | |||
Expression of MLANA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MLANA | 2315 | 206427_s_at | -0.0698 | 0.7492 | |
| GSE20347 | MLANA | 2315 | 206427_s_at | -0.0054 | 0.9440 | |
| GSE23400 | MLANA | 2315 | 206427_s_at | -0.1398 | 0.0010 | |
| GSE26886 | MLANA | 2315 | 206427_s_at | -0.0081 | 0.9516 | |
| GSE29001 | MLANA | 2315 | 206427_s_at | -0.2591 | 0.2568 | |
| GSE38129 | MLANA | 2315 | 206427_s_at | -0.1350 | 0.0270 | |
| GSE45670 | MLANA | 2315 | 206427_s_at | -0.0161 | 0.8383 | |
| GSE53622 | MLANA | 2315 | 7148 | -0.5864 | 0.0000 | |
| GSE53624 | MLANA | 2315 | 7148 | -0.5711 | 0.0000 | |
| GSE63941 | MLANA | 2315 | 206427_s_at | 0.1764 | 0.2711 | |
| GSE77861 | MLANA | 2315 | 206427_s_at | -0.1347 | 0.2359 | |
| GSE97050 | MLANA | 2315 | A_23_P43350 | -0.1314 | 0.5775 | |
| SRP133303 | MLANA | 2315 | RNAseq | -0.4681 | 0.0414 | |
| SRP193095 | MLANA | 2315 | RNAseq | -0.5131 | 0.0014 | |
| TCGA | MLANA | 2315 | RNAseq | -0.7239 | 0.0095 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MLANA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MLANA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MLANA | 2315 | 1 | 17 | 12 | |
| GSE20123 | MLANA | 2315 | 1 | 17 | 12 | |
| GSE43470 | MLANA | 2315 | 5 | 11 | 27 | |
| GSE46452 | MLANA | 2315 | 2 | 23 | 34 | |
| GSE47630 | MLANA | 2315 | 5 | 26 | 9 | |
| GSE54993 | MLANA | 2315 | 6 | 3 | 61 | |
| GSE54994 | MLANA | 2315 | 9 | 17 | 27 | |
| GSE60625 | MLANA | 2315 | 0 | 2 | 9 | |
| GSE74703 | MLANA | 2315 | 5 | 8 | 23 | |
| GSE74704 | MLANA | 2315 | 0 | 13 | 7 | |
| TCGA | MLANA | 2315 | 14 | 50 | 32 |
Total number of gains: 48; Total number of losses: 187; Total Number of normals: 253.
Somatic mutations of MLANA:
Generating mutation plots.
Highly correlated genes for MLANA:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MLANA | HNF4G | 0.693988 | 3 | 0 | 3 |
| MLANA | RBP2 | 0.673746 | 3 | 0 | 3 |
| MLANA | JAK3 | 0.65785 | 5 | 0 | 5 |
| MLANA | ZBTB33 | 0.655858 | 3 | 0 | 3 |
| MLANA | CSF1 | 0.650687 | 3 | 0 | 3 |
| MLANA | VPS52 | 0.647914 | 3 | 0 | 3 |
| MLANA | HAND1 | 0.645865 | 5 | 0 | 4 |
| MLANA | CACNB1 | 0.634261 | 6 | 0 | 5 |
| MLANA | MAPK4 | 0.633702 | 3 | 0 | 3 |
| MLANA | HTR1A | 0.629113 | 3 | 0 | 3 |
| MLANA | GPR3 | 0.628113 | 3 | 0 | 3 |
| MLANA | MIA | 0.626373 | 3 | 0 | 3 |
| MLANA | CLSTN2 | 0.623385 | 3 | 0 | 3 |
| MLANA | HAVCR1 | 0.62335 | 4 | 0 | 4 |
| MLANA | GMPPB | 0.621597 | 3 | 0 | 3 |
| MLANA | OLFM1 | 0.620541 | 5 | 0 | 4 |
| MLANA | SUGP1 | 0.61993 | 3 | 0 | 3 |
| MLANA | FGF4 | 0.619514 | 4 | 0 | 3 |
| MLANA | PDZD3 | 0.61928 | 4 | 0 | 3 |
| MLANA | DRD5 | 0.619026 | 5 | 0 | 5 |
For details and further investigation, click here
