| Full name: MLLT11 transcription factor 7 cofactor | Alias Symbol: AF1Q | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 10962 | HGNC ID: HGNC:16997 | Ensembl Gene: ENSG00000213190 | OMIM ID: 604684 |
| Drug and gene relationship at DGIdb | |||
Expression of MLLT11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MLLT11 | 10962 | 211071_s_at | 0.8710 | 0.3797 | |
| GSE20347 | MLLT11 | 10962 | 211071_s_at | 1.1850 | 0.0097 | |
| GSE23400 | MLLT11 | 10962 | 211071_s_at | 1.0390 | 0.0000 | |
| GSE26886 | MLLT11 | 10962 | 211071_s_at | 1.0280 | 0.0649 | |
| GSE29001 | MLLT11 | 10962 | 211071_s_at | 0.9999 | 0.0381 | |
| GSE38129 | MLLT11 | 10962 | 211071_s_at | 1.2683 | 0.0006 | |
| GSE45670 | MLLT11 | 10962 | 211071_s_at | 0.6399 | 0.2583 | |
| GSE53622 | MLLT11 | 10962 | 17555 | 1.8163 | 0.0000 | |
| GSE53624 | MLLT11 | 10962 | 17555 | 1.7305 | 0.0000 | |
| GSE63941 | MLLT11 | 10962 | 211071_s_at | -2.0819 | 0.2524 | |
| GSE77861 | MLLT11 | 10962 | 211071_s_at | 1.5089 | 0.0570 | |
| GSE97050 | MLLT11 | 10962 | A_23_P23346 | 0.7590 | 0.1434 | |
| SRP007169 | MLLT11 | 10962 | RNAseq | 1.2670 | 0.0743 | |
| SRP008496 | MLLT11 | 10962 | RNAseq | 2.3684 | 0.0022 | |
| SRP064894 | MLLT11 | 10962 | RNAseq | 1.7730 | 0.0000 | |
| SRP133303 | MLLT11 | 10962 | RNAseq | 1.4041 | 0.0001 | |
| SRP159526 | MLLT11 | 10962 | RNAseq | 3.3340 | 0.0000 | |
| SRP193095 | MLLT11 | 10962 | RNAseq | 1.9053 | 0.0000 | |
| SRP219564 | MLLT11 | 10962 | RNAseq | 0.7320 | 0.0803 | |
| TCGA | MLLT11 | 10962 | RNAseq | 0.5268 | 0.0027 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by MLLT11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MLLT11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MLLT11 | 10962 | 14 | 0 | 16 | |
| GSE20123 | MLLT11 | 10962 | 14 | 0 | 16 | |
| GSE43470 | MLLT11 | 10962 | 6 | 1 | 36 | |
| GSE46452 | MLLT11 | 10962 | 2 | 1 | 56 | |
| GSE47630 | MLLT11 | 10962 | 14 | 0 | 26 | |
| GSE54993 | MLLT11 | 10962 | 0 | 4 | 66 | |
| GSE54994 | MLLT11 | 10962 | 15 | 0 | 38 | |
| GSE60625 | MLLT11 | 10962 | 0 | 0 | 11 | |
| GSE74703 | MLLT11 | 10962 | 6 | 1 | 29 | |
| GSE74704 | MLLT11 | 10962 | 7 | 0 | 13 | |
| TCGA | MLLT11 | 10962 | 37 | 2 | 57 |
Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.
Somatic mutations of MLLT11:
Generating mutation plots.
Highly correlated genes for MLLT11:
Showing top 20/772 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MLLT11 | HAS3 | 0.787549 | 3 | 0 | 3 |
| MLLT11 | CYP20A1 | 0.778547 | 3 | 0 | 3 |
| MLLT11 | CPT1A | 0.777693 | 3 | 0 | 3 |
| MLLT11 | MAD2L2 | 0.733298 | 3 | 0 | 3 |
| MLLT11 | OGDH | 0.731688 | 3 | 0 | 3 |
| MLLT11 | PRTFDC1 | 0.712028 | 4 | 0 | 4 |
| MLLT11 | SNAP47 | 0.709091 | 3 | 0 | 3 |
| MLLT11 | EFTUD2 | 0.708627 | 3 | 0 | 3 |
| MLLT11 | CCDC51 | 0.703507 | 3 | 0 | 3 |
| MLLT11 | DCAF13 | 0.701243 | 4 | 0 | 4 |
| MLLT11 | PSMA5 | 0.698509 | 3 | 0 | 3 |
| MLLT11 | C1orf226 | 0.695813 | 3 | 0 | 3 |
| MLLT11 | ZC3H12C | 0.688332 | 3 | 0 | 3 |
| MLLT11 | AEBP2 | 0.686766 | 3 | 0 | 3 |
| MLLT11 | SCNM1 | 0.68668 | 3 | 0 | 3 |
| MLLT11 | EML4 | 0.686574 | 4 | 0 | 4 |
| MLLT11 | ORAI1 | 0.682378 | 3 | 0 | 3 |
| MLLT11 | CEP170 | 0.681376 | 3 | 0 | 3 |
| MLLT11 | TGFBR1 | 0.680006 | 3 | 0 | 3 |
| MLLT11 | TNFAIP1 | 0.677739 | 3 | 0 | 3 |
For details and further investigation, click here
