| Full name: syntaxin binding protein 5 like | Alias Symbol: KIAA1006|LLGL4 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 9515 | HGNC ID: HGNC:30757 | Ensembl Gene: ENSG00000145087 | OMIM ID: 609381 |
| Drug and gene relationship at DGIdb | |||
Expression of STXBP5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STXBP5L | 9515 | 215518_at | -0.0898 | 0.7383 | |
| GSE20347 | STXBP5L | 9515 | 215518_at | 0.0894 | 0.2921 | |
| GSE23400 | STXBP5L | 9515 | 215518_at | -0.0607 | 0.1190 | |
| GSE26886 | STXBP5L | 9515 | 215518_at | 0.1085 | 0.3018 | |
| GSE29001 | STXBP5L | 9515 | 215518_at | -0.1091 | 0.4194 | |
| GSE38129 | STXBP5L | 9515 | 215518_at | 0.0186 | 0.8505 | |
| GSE45670 | STXBP5L | 9515 | 215518_at | 0.0570 | 0.6629 | |
| GSE53622 | STXBP5L | 9515 | 43231 | -0.3409 | 0.0141 | |
| GSE53624 | STXBP5L | 9515 | 43231 | -0.5474 | 0.0001 | |
| GSE63941 | STXBP5L | 9515 | 215518_at | 0.0762 | 0.5389 | |
| GSE77861 | STXBP5L | 9515 | 215518_at | -0.0492 | 0.7481 | |
| GSE97050 | STXBP5L | 9515 | A_32_P95462 | 0.0456 | 0.8543 | |
| SRP133303 | STXBP5L | 9515 | RNAseq | 1.0152 | 0.0555 | |
| TCGA | STXBP5L | 9515 | RNAseq | -0.1312 | 0.8371 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STXBP5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STXBP5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STXBP5L | 9515 | 18 | 0 | 12 | |
| GSE20123 | STXBP5L | 9515 | 18 | 0 | 12 | |
| GSE43470 | STXBP5L | 9515 | 21 | 1 | 21 | |
| GSE46452 | STXBP5L | 9515 | 14 | 5 | 40 | |
| GSE47630 | STXBP5L | 9515 | 16 | 5 | 19 | |
| GSE54993 | STXBP5L | 9515 | 2 | 6 | 62 | |
| GSE54994 | STXBP5L | 9515 | 30 | 4 | 19 | |
| GSE60625 | STXBP5L | 9515 | 0 | 6 | 5 | |
| GSE74703 | STXBP5L | 9515 | 17 | 1 | 18 | |
| GSE74704 | STXBP5L | 9515 | 13 | 0 | 7 | |
| TCGA | STXBP5L | 9515 | 53 | 7 | 36 |
Total number of gains: 202; Total number of losses: 35; Total Number of normals: 251.
Somatic mutations of STXBP5L:
Generating mutation plots.
Highly correlated genes for STXBP5L:
Showing top 20/309 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STXBP5L | TBR1 | 0.691383 | 3 | 0 | 3 |
| STXBP5L | GNRHR | 0.685853 | 3 | 0 | 3 |
| STXBP5L | PPP1R3A | 0.670964 | 3 | 0 | 3 |
| STXBP5L | MMP26 | 0.664049 | 4 | 0 | 4 |
| STXBP5L | OR1A1 | 0.660155 | 4 | 0 | 4 |
| STXBP5L | SERPINA4 | 0.659269 | 3 | 0 | 3 |
| STXBP5L | PDE6H | 0.658137 | 3 | 0 | 3 |
| STXBP5L | CA1 | 0.65784 | 3 | 0 | 3 |
| STXBP5L | CALCB | 0.654229 | 3 | 0 | 3 |
| STXBP5L | MC2R | 0.651273 | 5 | 0 | 4 |
| STXBP5L | ARHGEF38 | 0.650566 | 4 | 0 | 3 |
| STXBP5L | FGA | 0.650434 | 3 | 0 | 3 |
| STXBP5L | OR2S2 | 0.65034 | 3 | 0 | 3 |
| STXBP5L | TM4SF4 | 0.649938 | 4 | 0 | 3 |
| STXBP5L | FSCN3 | 0.647448 | 7 | 0 | 5 |
| STXBP5L | ACRV1 | 0.646336 | 4 | 0 | 3 |
| STXBP5L | APOH | 0.646215 | 3 | 0 | 3 |
| STXBP5L | FGG | 0.646167 | 4 | 0 | 3 |
| STXBP5L | OR10H3 | 0.64533 | 5 | 0 | 4 |
| STXBP5L | PPP1R14D | 0.641431 | 5 | 0 | 4 |
For details and further investigation, click here
