| Full name: WAS/WASL interacting protein family member 1 | Alias Symbol: WIP | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 7456 | HGNC ID: HGNC:12736 | Ensembl Gene: ENSG00000115935 | OMIM ID: 602357 |
| Drug and gene relationship at DGIdb | |||
Expression of WIPF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WIPF1 | 7456 | 202664_at | 0.0394 | 0.9793 | |
| GSE20347 | WIPF1 | 7456 | 202664_at | 0.5748 | 0.0394 | |
| GSE23400 | WIPF1 | 7456 | 202665_s_at | 0.2080 | 0.0006 | |
| GSE26886 | WIPF1 | 7456 | 202664_at | 1.0745 | 0.0497 | |
| GSE29001 | WIPF1 | 7456 | 202664_at | 0.7697 | 0.0910 | |
| GSE38129 | WIPF1 | 7456 | 202664_at | 0.2773 | 0.4428 | |
| GSE45670 | WIPF1 | 7456 | 202664_at | -0.7201 | 0.0738 | |
| GSE53622 | WIPF1 | 7456 | 44750 | 0.5733 | 0.0000 | |
| GSE53624 | WIPF1 | 7456 | 44750 | 0.5502 | 0.0000 | |
| GSE63941 | WIPF1 | 7456 | 202664_at | -3.1284 | 0.0232 | |
| GSE77861 | WIPF1 | 7456 | 202664_at | 0.6390 | 0.0212 | |
| GSE97050 | WIPF1 | 7456 | A_23_P330616 | 0.6131 | 0.0997 | |
| SRP007169 | WIPF1 | 7456 | RNAseq | 2.2046 | 0.0002 | |
| SRP008496 | WIPF1 | 7456 | RNAseq | 2.2332 | 0.0000 | |
| SRP064894 | WIPF1 | 7456 | RNAseq | 0.9673 | 0.0001 | |
| SRP133303 | WIPF1 | 7456 | RNAseq | 0.5764 | 0.0035 | |
| SRP159526 | WIPF1 | 7456 | RNAseq | -0.1433 | 0.7600 | |
| SRP193095 | WIPF1 | 7456 | RNAseq | 0.6735 | 0.0053 | |
| SRP219564 | WIPF1 | 7456 | RNAseq | 0.8487 | 0.0394 | |
| TCGA | WIPF1 | 7456 | RNAseq | 0.0417 | 0.6562 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by WIPF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WIPF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WIPF1 | 7456 | 9 | 0 | 21 | |
| GSE20123 | WIPF1 | 7456 | 9 | 0 | 21 | |
| GSE43470 | WIPF1 | 7456 | 6 | 1 | 36 | |
| GSE46452 | WIPF1 | 7456 | 1 | 4 | 54 | |
| GSE47630 | WIPF1 | 7456 | 5 | 3 | 32 | |
| GSE54993 | WIPF1 | 7456 | 0 | 5 | 65 | |
| GSE54994 | WIPF1 | 7456 | 11 | 4 | 38 | |
| GSE60625 | WIPF1 | 7456 | 0 | 3 | 8 | |
| GSE74703 | WIPF1 | 7456 | 5 | 1 | 30 | |
| GSE74704 | WIPF1 | 7456 | 5 | 0 | 15 | |
| TCGA | WIPF1 | 7456 | 29 | 5 | 62 |
Total number of gains: 80; Total number of losses: 26; Total Number of normals: 382.
Somatic mutations of WIPF1:
Generating mutation plots.
Highly correlated genes for WIPF1:
Showing top 20/1152 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WIPF1 | CLEC14A | 0.801997 | 3 | 0 | 3 |
| WIPF1 | MOB3A | 0.78083 | 3 | 0 | 3 |
| WIPF1 | MYCT1 | 0.737679 | 3 | 0 | 3 |
| WIPF1 | ELF4 | 0.732554 | 3 | 0 | 3 |
| WIPF1 | ANXA6 | 0.729891 | 11 | 0 | 10 |
| WIPF1 | HDAC2 | 0.729745 | 3 | 0 | 3 |
| WIPF1 | RNF13 | 0.723779 | 3 | 0 | 3 |
| WIPF1 | TMTC4 | 0.721903 | 3 | 0 | 3 |
| WIPF1 | CRKL | 0.720476 | 3 | 0 | 3 |
| WIPF1 | SHANK3 | 0.720405 | 3 | 0 | 3 |
| WIPF1 | SRGN | 0.718434 | 11 | 0 | 11 |
| WIPF1 | ECSCR | 0.717031 | 4 | 0 | 4 |
| WIPF1 | RAB11FIP5 | 0.715093 | 3 | 0 | 3 |
| WIPF1 | ZEB2 | 0.712291 | 9 | 0 | 9 |
| WIPF1 | SPATA13 | 0.70871 | 6 | 0 | 6 |
| WIPF1 | PLEKHO1 | 0.707283 | 11 | 0 | 11 |
| WIPF1 | GPC6 | 0.706379 | 5 | 0 | 5 |
| WIPF1 | UBA2 | 0.706246 | 4 | 0 | 4 |
| WIPF1 | SESTD1 | 0.70533 | 3 | 0 | 3 |
| WIPF1 | TUBG1 | 0.703711 | 3 | 0 | 3 |
For details and further investigation, click here
