| Full name: molybdenum cofactor synthesis 1 | Alias Symbol: MOCOD | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 4337 | HGNC ID: HGNC:7190 | Ensembl Gene: ENSG00000124615 | OMIM ID: 603707 |
| Drug and gene relationship at DGIdb | |||
Expression of MOCS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOCS1 | 4337 | 213181_s_at | -0.0230 | 0.9779 | |
| GSE20347 | MOCS1 | 4337 | 211673_s_at | -0.1172 | 0.2432 | |
| GSE23400 | MOCS1 | 4337 | 213181_s_at | -0.1450 | 0.0003 | |
| GSE26886 | MOCS1 | 4337 | 213181_s_at | -0.2608 | 0.2051 | |
| GSE29001 | MOCS1 | 4337 | 213181_s_at | -0.0650 | 0.7166 | |
| GSE38129 | MOCS1 | 4337 | 213181_s_at | -0.3774 | 0.0339 | |
| GSE45670 | MOCS1 | 4337 | 211673_s_at | -0.2355 | 0.1555 | |
| GSE53622 | MOCS1 | 4337 | 53554 | -0.0816 | 0.4598 | |
| GSE53624 | MOCS1 | 4337 | 53554 | 0.0189 | 0.8300 | |
| GSE63941 | MOCS1 | 4337 | 211673_s_at | -0.9896 | 0.0121 | |
| GSE77861 | MOCS1 | 4337 | 213181_s_at | -0.0286 | 0.8742 | |
| GSE97050 | MOCS1 | 4337 | A_23_P58993 | 0.0807 | 0.7666 | |
| SRP007169 | MOCS1 | 4337 | RNAseq | -0.0721 | 0.9064 | |
| SRP064894 | MOCS1 | 4337 | RNAseq | 0.4995 | 0.0657 | |
| SRP133303 | MOCS1 | 4337 | RNAseq | -0.3584 | 0.2268 | |
| SRP159526 | MOCS1 | 4337 | RNAseq | -0.4776 | 0.1403 | |
| SRP193095 | MOCS1 | 4337 | RNAseq | 0.0477 | 0.7702 | |
| SRP219564 | MOCS1 | 4337 | RNAseq | -0.5956 | 0.1327 | |
| TCGA | MOCS1 | 4337 | RNAseq | -0.4757 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MOCS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOCS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOCS1 | 4337 | 4 | 1 | 25 | |
| GSE20123 | MOCS1 | 4337 | 4 | 1 | 25 | |
| GSE43470 | MOCS1 | 4337 | 6 | 0 | 37 | |
| GSE46452 | MOCS1 | 4337 | 2 | 9 | 48 | |
| GSE47630 | MOCS1 | 4337 | 8 | 4 | 28 | |
| GSE54993 | MOCS1 | 4337 | 3 | 2 | 65 | |
| GSE54994 | MOCS1 | 4337 | 11 | 4 | 38 | |
| GSE60625 | MOCS1 | 4337 | 0 | 1 | 10 | |
| GSE74703 | MOCS1 | 4337 | 6 | 0 | 30 | |
| GSE74704 | MOCS1 | 4337 | 1 | 1 | 18 | |
| TCGA | MOCS1 | 4337 | 18 | 14 | 64 |
Total number of gains: 63; Total number of losses: 37; Total Number of normals: 388.
Somatic mutations of MOCS1:
Generating mutation plots.
Highly correlated genes for MOCS1:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOCS1 | MAGEH1 | 0.742215 | 3 | 0 | 3 |
| MOCS1 | ARSK | 0.701899 | 3 | 0 | 3 |
| MOCS1 | NES | 0.680219 | 3 | 0 | 3 |
| MOCS1 | TEK | 0.679673 | 3 | 0 | 3 |
| MOCS1 | FSTL1 | 0.679388 | 3 | 0 | 3 |
| MOCS1 | COL15A1 | 0.669895 | 3 | 0 | 3 |
| MOCS1 | PRKACG | 0.668047 | 3 | 0 | 3 |
| MOCS1 | G0S2 | 0.663059 | 3 | 0 | 3 |
| MOCS1 | IMPAD1 | 0.662346 | 3 | 0 | 3 |
| MOCS1 | TNFRSF10D | 0.660974 | 3 | 0 | 3 |
| MOCS1 | GPM6B | 0.660786 | 4 | 0 | 3 |
| MOCS1 | LRRC17 | 0.65819 | 3 | 0 | 3 |
| MOCS1 | TGM2 | 0.658009 | 3 | 0 | 3 |
| MOCS1 | EMCN | 0.653204 | 4 | 0 | 4 |
| MOCS1 | ST3GAL2 | 0.650812 | 4 | 0 | 3 |
| MOCS1 | VKORC1 | 0.649805 | 3 | 0 | 3 |
| MOCS1 | MAPK8IP3 | 0.648389 | 3 | 0 | 3 |
| MOCS1 | SSPN | 0.647392 | 3 | 0 | 3 |
| MOCS1 | LAPTM4A | 0.646044 | 4 | 0 | 4 |
| MOCS1 | DPP4 | 0.643595 | 4 | 0 | 4 |
For details and further investigation, click here
