| Full name: mannose phosphate isomerase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q24.1 | ||
| Entrez ID: 4351 | HGNC ID: HGNC:7216 | Ensembl Gene: ENSG00000178802 | OMIM ID: 154550 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MPI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPI | 4351 | 202472_at | -0.6410 | 0.1515 | |
| GSE20347 | MPI | 4351 | 202472_at | -0.2094 | 0.2151 | |
| GSE23400 | MPI | 4351 | 202472_at | -0.0689 | 0.2219 | |
| GSE26886 | MPI | 4351 | 202472_at | -0.1265 | 0.4504 | |
| GSE29001 | MPI | 4351 | 202472_at | -0.6190 | 0.0248 | |
| GSE38129 | MPI | 4351 | 202472_at | -0.0427 | 0.8029 | |
| GSE45670 | MPI | 4351 | 202472_at | -0.0569 | 0.7985 | |
| GSE53622 | MPI | 4351 | 127075 | -0.3912 | 0.0000 | |
| GSE53624 | MPI | 4351 | 127075 | -0.6367 | 0.0000 | |
| GSE63941 | MPI | 4351 | 202472_at | 1.1044 | 0.0151 | |
| GSE77861 | MPI | 4351 | 202472_at | -0.2034 | 0.4220 | |
| GSE97050 | MPI | 4351 | A_23_P60579 | -0.1933 | 0.3789 | |
| SRP007169 | MPI | 4351 | RNAseq | -0.7910 | 0.0450 | |
| SRP008496 | MPI | 4351 | RNAseq | -0.8284 | 0.0168 | |
| SRP064894 | MPI | 4351 | RNAseq | -0.2825 | 0.1846 | |
| SRP133303 | MPI | 4351 | RNAseq | -0.4122 | 0.0106 | |
| SRP159526 | MPI | 4351 | RNAseq | -0.3796 | 0.1204 | |
| SRP193095 | MPI | 4351 | RNAseq | -0.4287 | 0.0000 | |
| SRP219564 | MPI | 4351 | RNAseq | -0.4021 | 0.0911 | |
| TCGA | MPI | 4351 | RNAseq | -0.0679 | 0.2366 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MPI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPI | 4351 | 8 | 1 | 21 | |
| GSE20123 | MPI | 4351 | 8 | 1 | 21 | |
| GSE43470 | MPI | 4351 | 4 | 6 | 33 | |
| GSE46452 | MPI | 4351 | 3 | 7 | 49 | |
| GSE47630 | MPI | 4351 | 8 | 10 | 22 | |
| GSE54993 | MPI | 4351 | 5 | 6 | 59 | |
| GSE54994 | MPI | 4351 | 5 | 7 | 41 | |
| GSE60625 | MPI | 4351 | 4 | 0 | 7 | |
| GSE74703 | MPI | 4351 | 4 | 3 | 29 | |
| GSE74704 | MPI | 4351 | 4 | 1 | 15 | |
| TCGA | MPI | 4351 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 57; Total Number of normals: 364.
Somatic mutations of MPI:
Generating mutation plots.
Highly correlated genes for MPI:
Showing top 20/415 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPI | CCNC | 0.723099 | 3 | 0 | 3 |
| MPI | TMEM107 | 0.714706 | 3 | 0 | 3 |
| MPI | NUP188 | 0.70939 | 3 | 0 | 3 |
| MPI | GPX1 | 0.708869 | 4 | 0 | 3 |
| MPI | UQCRQ | 0.702953 | 3 | 0 | 3 |
| MPI | TAF12 | 0.69837 | 4 | 0 | 4 |
| MPI | TOMM22 | 0.688829 | 3 | 0 | 3 |
| MPI | SLC12A6 | 0.682606 | 4 | 0 | 3 |
| MPI | SNX17 | 0.68097 | 4 | 0 | 3 |
| MPI | ABHD14B | 0.678815 | 4 | 0 | 4 |
| MPI | TALDO1 | 0.668323 | 3 | 0 | 3 |
| MPI | UNK | 0.665635 | 3 | 0 | 3 |
| MPI | CRYZ | 0.665419 | 4 | 0 | 3 |
| MPI | C12orf29 | 0.66265 | 4 | 0 | 4 |
| MPI | LRRN1 | 0.661273 | 3 | 0 | 3 |
| MPI | MCCC2 | 0.660501 | 3 | 0 | 3 |
| MPI | SCAMP2 | 0.65495 | 6 | 0 | 5 |
| MPI | TGM3 | 0.652567 | 4 | 0 | 3 |
| MPI | FAM174A | 0.652524 | 4 | 0 | 3 |
| MPI | CCNDBP1 | 0.651223 | 4 | 0 | 3 |
For details and further investigation, click here
