| Full name: TATA-box binding protein associated factor 12 | Alias Symbol: TAFII20 | ||
| Type: protein-coding gene | Cytoband: 1p35.3 | ||
| Entrez ID: 6883 | HGNC ID: HGNC:11545 | Ensembl Gene: ENSG00000120656 | OMIM ID: 600773 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF12 | 6883 | 209463_s_at | -0.0961 | 0.7628 | |
| GSE20347 | TAF12 | 6883 | 209463_s_at | -0.1033 | 0.5455 | |
| GSE23400 | TAF12 | 6883 | 209463_s_at | 0.1436 | 0.0151 | |
| GSE26886 | TAF12 | 6883 | 209463_s_at | 0.0805 | 0.7798 | |
| GSE29001 | TAF12 | 6883 | 209463_s_at | 0.0666 | 0.8695 | |
| GSE38129 | TAF12 | 6883 | 209463_s_at | 0.1508 | 0.4261 | |
| GSE45670 | TAF12 | 6883 | 209463_s_at | 0.0206 | 0.9100 | |
| GSE53622 | TAF12 | 6883 | 10222 | 0.1490 | 0.0212 | |
| GSE53624 | TAF12 | 6883 | 10222 | 0.0674 | 0.3174 | |
| GSE63941 | TAF12 | 6883 | 209463_s_at | 0.0669 | 0.8957 | |
| GSE77861 | TAF12 | 6883 | 209463_s_at | -0.3220 | 0.3170 | |
| GSE97050 | TAF12 | 6883 | A_23_P63178 | 0.2227 | 0.3881 | |
| SRP007169 | TAF12 | 6883 | RNAseq | -0.5599 | 0.2331 | |
| SRP008496 | TAF12 | 6883 | RNAseq | -0.6371 | 0.0167 | |
| SRP064894 | TAF12 | 6883 | RNAseq | 0.4053 | 0.0523 | |
| SRP133303 | TAF12 | 6883 | RNAseq | 0.2596 | 0.1477 | |
| SRP159526 | TAF12 | 6883 | RNAseq | -0.2469 | 0.1326 | |
| SRP193095 | TAF12 | 6883 | RNAseq | -0.2952 | 0.0072 | |
| SRP219564 | TAF12 | 6883 | RNAseq | -0.2369 | 0.4342 | |
| TCGA | TAF12 | 6883 | RNAseq | 0.2356 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF12 | 6883 | 0 | 6 | 24 | |
| GSE20123 | TAF12 | 6883 | 0 | 5 | 25 | |
| GSE43470 | TAF12 | 6883 | 3 | 6 | 34 | |
| GSE46452 | TAF12 | 6883 | 5 | 1 | 53 | |
| GSE47630 | TAF12 | 6883 | 8 | 3 | 29 | |
| GSE54993 | TAF12 | 6883 | 2 | 1 | 67 | |
| GSE54994 | TAF12 | 6883 | 10 | 4 | 39 | |
| GSE60625 | TAF12 | 6883 | 0 | 0 | 11 | |
| GSE74703 | TAF12 | 6883 | 2 | 4 | 30 | |
| GSE74704 | TAF12 | 6883 | 0 | 0 | 20 | |
| TCGA | TAF12 | 6883 | 11 | 21 | 64 |
Total number of gains: 41; Total number of losses: 51; Total Number of normals: 396.
Somatic mutations of TAF12:
Generating mutation plots.
Highly correlated genes for TAF12:
Showing top 20/216 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF12 | HUS1 | 0.741609 | 3 | 0 | 3 |
| TAF12 | TMED9 | 0.734665 | 3 | 0 | 3 |
| TAF12 | POLD4 | 0.731788 | 3 | 0 | 3 |
| TAF12 | USP32 | 0.708314 | 3 | 0 | 3 |
| TAF12 | STAU2 | 0.705934 | 3 | 0 | 3 |
| TAF12 | COPS2 | 0.70425 | 3 | 0 | 3 |
| TAF12 | PCNP | 0.70357 | 3 | 0 | 3 |
| TAF12 | HSPA4L | 0.702653 | 4 | 0 | 3 |
| TAF12 | MPI | 0.69837 | 4 | 0 | 4 |
| TAF12 | APPL2 | 0.69623 | 4 | 0 | 3 |
| TAF12 | EGLN1 | 0.696228 | 3 | 0 | 3 |
| TAF12 | TNIP1 | 0.695556 | 3 | 0 | 3 |
| TAF12 | SLC35A3 | 0.690265 | 3 | 0 | 3 |
| TAF12 | ZMIZ1 | 0.687912 | 3 | 0 | 3 |
| TAF12 | RWDD2A | 0.683581 | 4 | 0 | 4 |
| TAF12 | TK2 | 0.679469 | 4 | 0 | 3 |
| TAF12 | SLC2A9 | 0.677574 | 3 | 0 | 3 |
| TAF12 | B3GALT2 | 0.677199 | 3 | 0 | 3 |
| TAF12 | COBLL1 | 0.676073 | 3 | 0 | 3 |
| TAF12 | CCL28 | 0.675275 | 3 | 0 | 3 |
For details and further investigation, click here
