| Full name: U2 small nuclear RNA auxiliary factor 1 like 4 | Alias Symbol: MGC33901|U2af26 | ||
| Type: protein-coding gene | Cytoband: 19q13.13 | ||
| Entrez ID: 199746 | HGNC ID: HGNC:23020 | Ensembl Gene: ENSG00000161265 | OMIM ID: 601080 |
| Drug and gene relationship at DGIdb | |||
U2AF1L4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05131 | Shigellosis |
Expression of U2AF1L4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | U2AF1L4 | 199746 | 226700_at | -0.3513 | 0.5548 | |
| GSE26886 | U2AF1L4 | 199746 | 226700_at | 0.2416 | 0.1566 | |
| GSE45670 | U2AF1L4 | 199746 | 226700_at | -0.2463 | 0.2391 | |
| GSE63941 | U2AF1L4 | 199746 | 226700_at | 0.8773 | 0.2853 | |
| GSE77861 | U2AF1L4 | 199746 | 226700_at | 0.0451 | 0.8551 | |
| GSE97050 | U2AF1L4 | 199746 | A_23_P326296 | -0.1670 | 0.5676 | |
| SRP064894 | U2AF1L4 | 199746 | RNAseq | 0.5912 | 0.0152 | |
| SRP133303 | U2AF1L4 | 199746 | RNAseq | -0.1883 | 0.3629 | |
| SRP159526 | U2AF1L4 | 199746 | RNAseq | -0.0297 | 0.9079 | |
| SRP193095 | U2AF1L4 | 199746 | RNAseq | 0.0666 | 0.6708 | |
| SRP219564 | U2AF1L4 | 199746 | RNAseq | 0.0617 | 0.8587 | |
| TCGA | U2AF1L4 | 199746 | RNAseq | -0.0446 | 0.6268 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by U2AF1L4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of U2AF1L4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | U2AF1L4 | 199746 | 7 | 4 | 19 | |
| GSE20123 | U2AF1L4 | 199746 | 7 | 3 | 20 | |
| GSE43470 | U2AF1L4 | 199746 | 3 | 7 | 33 | |
| GSE46452 | U2AF1L4 | 199746 | 48 | 1 | 10 | |
| GSE47630 | U2AF1L4 | 199746 | 9 | 5 | 26 | |
| GSE54993 | U2AF1L4 | 199746 | 17 | 3 | 50 | |
| GSE54994 | U2AF1L4 | 199746 | 7 | 9 | 37 | |
| GSE60625 | U2AF1L4 | 199746 | 9 | 0 | 2 | |
| GSE74703 | U2AF1L4 | 199746 | 3 | 4 | 29 | |
| GSE74704 | U2AF1L4 | 199746 | 6 | 1 | 13 | |
| TCGA | U2AF1L4 | 199746 | 22 | 10 | 64 |
Total number of gains: 138; Total number of losses: 47; Total Number of normals: 303.
Somatic mutations of U2AF1L4:
Generating mutation plots.
Highly correlated genes for U2AF1L4:
Showing top 20/32 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| U2AF1L4 | SLC2A11 | 0.753691 | 3 | 0 | 3 |
| U2AF1L4 | GNAZ | 0.743447 | 3 | 0 | 3 |
| U2AF1L4 | CALCOCO1 | 0.738033 | 3 | 0 | 3 |
| U2AF1L4 | MCF2L | 0.718602 | 3 | 0 | 3 |
| U2AF1L4 | SHC2 | 0.705271 | 4 | 0 | 4 |
| U2AF1L4 | CHST10 | 0.681346 | 4 | 0 | 3 |
| U2AF1L4 | MPP3 | 0.680802 | 3 | 0 | 3 |
| U2AF1L4 | SCN5A | 0.680484 | 3 | 0 | 3 |
| U2AF1L4 | OSBPL5 | 0.666442 | 3 | 0 | 3 |
| U2AF1L4 | PHF1 | 0.664289 | 4 | 0 | 3 |
| U2AF1L4 | OTOF | 0.623047 | 3 | 0 | 3 |
| U2AF1L4 | JAKMIP2 | 0.614314 | 3 | 0 | 3 |
| U2AF1L4 | ZNF302 | 0.609223 | 4 | 0 | 3 |
| U2AF1L4 | ZBED3 | 0.606036 | 4 | 0 | 3 |
| U2AF1L4 | TSPAN18 | 0.602029 | 3 | 0 | 3 |
| U2AF1L4 | NT5C3B | 0.599479 | 3 | 0 | 3 |
| U2AF1L4 | RPRM | 0.598407 | 5 | 0 | 3 |
| U2AF1L4 | NBEA | 0.593245 | 3 | 0 | 3 |
| U2AF1L4 | ZNF527 | 0.59034 | 5 | 0 | 3 |
| U2AF1L4 | FBXO17 | 0.588906 | 5 | 0 | 4 |
For details and further investigation, click here
