| Full name: membrane palmitoylated protein 6 | Alias Symbol: PALS2|VAM-1|p55T | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 51678 | HGNC ID: HGNC:18167 | Ensembl Gene: ENSG00000105926 | OMIM ID: 606959 |
| Drug and gene relationship at DGIdb | |||
Expression of MPP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPP6 | 51678 | 205429_s_at | 0.4557 | 0.5148 | |
| GSE20347 | MPP6 | 51678 | 205429_s_at | 0.5841 | 0.0222 | |
| GSE23400 | MPP6 | 51678 | 205429_s_at | 0.1622 | 0.0000 | |
| GSE26886 | MPP6 | 51678 | 205429_s_at | 0.6260 | 0.0972 | |
| GSE29001 | MPP6 | 51678 | 205429_s_at | 0.8783 | 0.0221 | |
| GSE38129 | MPP6 | 51678 | 205429_s_at | 0.8610 | 0.0000 | |
| GSE45670 | MPP6 | 51678 | 205429_s_at | 0.3542 | 0.2543 | |
| GSE53622 | MPP6 | 51678 | 110255 | 0.3269 | 0.0036 | |
| GSE53624 | MPP6 | 51678 | 110255 | 0.7290 | 0.0000 | |
| GSE63941 | MPP6 | 51678 | 205429_s_at | 0.8262 | 0.3106 | |
| GSE77861 | MPP6 | 51678 | 205429_s_at | 0.0441 | 0.7589 | |
| GSE97050 | MPP6 | 51678 | A_23_P71053 | 0.0440 | 0.8959 | |
| SRP007169 | MPP6 | 51678 | RNAseq | 0.0537 | 0.9180 | |
| SRP008496 | MPP6 | 51678 | RNAseq | 0.3682 | 0.2825 | |
| SRP064894 | MPP6 | 51678 | RNAseq | 0.0212 | 0.8953 | |
| SRP133303 | MPP6 | 51678 | RNAseq | 0.2198 | 0.3137 | |
| SRP159526 | MPP6 | 51678 | RNAseq | 0.2269 | 0.5019 | |
| SRP193095 | MPP6 | 51678 | RNAseq | 0.1126 | 0.5326 | |
| SRP219564 | MPP6 | 51678 | RNAseq | 0.2034 | 0.6726 | |
| TCGA | MPP6 | 51678 | RNAseq | 0.1620 | 0.1719 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPP6 | 51678 | 17 | 1 | 12 | |
| GSE20123 | MPP6 | 51678 | 17 | 1 | 12 | |
| GSE43470 | MPP6 | 51678 | 4 | 0 | 39 | |
| GSE46452 | MPP6 | 51678 | 10 | 2 | 47 | |
| GSE47630 | MPP6 | 51678 | 9 | 1 | 30 | |
| GSE54993 | MPP6 | 51678 | 0 | 6 | 64 | |
| GSE54994 | MPP6 | 51678 | 21 | 2 | 30 | |
| GSE60625 | MPP6 | 51678 | 0 | 0 | 11 | |
| GSE74703 | MPP6 | 51678 | 4 | 0 | 32 | |
| GSE74704 | MPP6 | 51678 | 11 | 1 | 8 | |
| TCGA | MPP6 | 51678 | 56 | 5 | 35 |
Total number of gains: 149; Total number of losses: 19; Total Number of normals: 320.
Somatic mutations of MPP6:
Generating mutation plots.
Highly correlated genes for MPP6:
Showing top 20/809 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPP6 | UBLCP1 | 0.781014 | 3 | 0 | 3 |
| MPP6 | ASF1A | 0.776393 | 3 | 0 | 3 |
| MPP6 | MRPL30 | 0.750773 | 3 | 0 | 3 |
| MPP6 | ERCC8 | 0.734662 | 4 | 0 | 4 |
| MPP6 | NUDT15 | 0.724154 | 3 | 0 | 3 |
| MPP6 | THBD | 0.710536 | 3 | 0 | 3 |
| MPP6 | FAM98A | 0.705039 | 4 | 0 | 4 |
| MPP6 | UTP15 | 0.7031 | 4 | 0 | 3 |
| MPP6 | PPP2R3C | 0.696572 | 4 | 0 | 3 |
| MPP6 | RASA1 | 0.685292 | 3 | 0 | 3 |
| MPP6 | UBP1 | 0.682237 | 3 | 0 | 3 |
| MPP6 | USP11 | 0.682141 | 3 | 0 | 3 |
| MPP6 | ATP6V1C1 | 0.675902 | 8 | 0 | 8 |
| MPP6 | C16orf87 | 0.674885 | 5 | 0 | 4 |
| MPP6 | SLC7A6OS | 0.67463 | 4 | 0 | 3 |
| MPP6 | MORC4 | 0.673624 | 5 | 0 | 5 |
| MPP6 | MRPS28 | 0.672393 | 8 | 0 | 7 |
| MPP6 | PDE8A | 0.671604 | 4 | 0 | 4 |
| MPP6 | EAF1 | 0.669201 | 4 | 0 | 3 |
| MPP6 | LRRC8A | 0.667446 | 3 | 0 | 3 |
For details and further investigation, click here
