MPV17L2

 

Full name: MPV17 mitochondrial inner membrane protein like 2 Alias Symbol: FKSG24|MGC12972
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 84769 HGNC ID: HGNC:28177 Ensembl Gene: ENSG00000254858 OMIM ID: 616133
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MPV17L2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MPV17L2 84769 223473_at 0.4473 0.3926
GSE26886 MPV17L2 84769 223473_at 0.0958 0.5279
GSE45670 MPV17L2 84769 223473_at 0.3343 0.0338
GSE53622 MPV17L2 84769 3484 0.5580 0.0000
GSE53624 MPV17L2 84769 3484 0.7504 0.0000
GSE63941 MPV17L2 84769 223473_at 0.3697 0.2820
GSE77861 MPV17L2 84769 223473_at 0.1061 0.4196
GSE97050 MPV17L2 84769 A_23_P165130 0.4649 0.1399
SRP007169 MPV17L2 84769 RNAseq 0.4971 0.3021
SRP008496 MPV17L2 84769 RNAseq 0.7925 0.0149
SRP064894 MPV17L2 84769 RNAseq 0.9284 0.0001
SRP133303 MPV17L2 84769 RNAseq 0.5119 0.0385
SRP159526 MPV17L2 84769 RNAseq 0.8967 0.0033
SRP193095 MPV17L2 84769 RNAseq 0.2605 0.0793
SRP219564 MPV17L2 84769 RNAseq 0.2917 0.5859
TCGA MPV17L2 84769 RNAseq 0.0507 0.4590

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MPV17L2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MPV17L2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MPV17L2 84769 4 4 22
GSE20123 MPV17L2 84769 3 2 25
GSE43470 MPV17L2 84769 2 6 35
GSE46452 MPV17L2 84769 47 1 11
GSE47630 MPV17L2 84769 4 8 28
GSE54993 MPV17L2 84769 15 4 51
GSE54994 MPV17L2 84769 6 13 34
GSE60625 MPV17L2 84769 9 0 2
GSE74703 MPV17L2 84769 2 4 30
GSE74704 MPV17L2 84769 0 2 18
TCGA MPV17L2 84769 17 9 70

Total number of gains: 109; Total number of losses: 53; Total Number of normals: 326.  

 

Somatic mutations of MPV17L2:

 

Generating mutation plots.

 

Highly correlated genes for MPV17L2:

 

Showing top 20/518 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MPV17L2CDK2AP10.706818303
MPV17L2TBRG40.704571303
MPV17L2TUBGCP20.691002303
MPV17L2MMP10.682131404
MPV17L2GRIN2D0.681656303
MPV17L2C12orf100.673687505
MPV17L2ZNF5980.671655606
MPV17L2APOC10.656881303
MPV17L2NTMT10.653668403
MPV17L2WDR240.649547404
MPV17L2SLC25A320.649454303
MPV17L2VKORC1L10.645817303
MPV17L2POLR3K0.645749606
MPV17L2PDIA50.644314303
MPV17L2ACOT70.643152605
MPV17L2TSC20.643018303
MPV17L2HPS60.642435303
MPV17L2NABP20.642072605
MPV17L2LOXL20.640319404
MPV17L2MRPL380.639738303

For details and further investigation, click here