ACOT7

 

Full name: acyl-CoA thioesterase 7 Alias Symbol: BACH|ACH1|ACT|CTE-II|LACH1|MGC1126|hBACH
Type: protein-coding gene Cytoband: 1p36.31
Entrez ID: 11332 HGNC ID: HGNC:24157 Ensembl Gene: ENSG00000097021 OMIM ID: 602587
Drug and gene relationship at DGIdb

 

Expression of ACOT7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ACOT7 11332 208002_s_at 0.9351 0.0481
GSE20347 ACOT7 11332 208002_s_at 0.7070 0.0003
GSE23400 ACOT7 11332 208002_s_at 0.6923 0.0000
GSE26886 ACOT7 11332 208002_s_at 1.1054 0.0001
GSE29001 ACOT7 11332 208002_s_at 0.8132 0.0024
GSE38129 ACOT7 11332 208002_s_at 0.9884 0.0000
GSE45670 ACOT7 11332 208002_s_at 1.0776 0.0005
GSE53622 ACOT7 11332 154874 0.7549 0.0000
GSE53624 ACOT7 11332 154874 0.9341 0.0000
GSE63941 ACOT7 11332 208002_s_at 0.6957 0.2641
GSE77861 ACOT7 11332 208002_s_at 0.8519 0.0244
GSE97050 ACOT7 11332 A_24_P205589 1.0205 0.1204
SRP007169 ACOT7 11332 RNAseq 2.0937 0.0046
SRP008496 ACOT7 11332 RNAseq 1.3705 0.0127
SRP064894 ACOT7 11332 RNAseq 1.1240 0.0000
SRP133303 ACOT7 11332 RNAseq 1.5442 0.0000
SRP159526 ACOT7 11332 RNAseq 0.6456 0.0088
SRP193095 ACOT7 11332 RNAseq 0.7967 0.0000
SRP219564 ACOT7 11332 RNAseq 1.0137 0.0560
TCGA ACOT7 11332 RNAseq 0.4693 0.0000

Upregulated datasets: 6; Downregulated datasets: 0.  

 

Survival by ACOT7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ACOT7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ACOT7 11332 3 6 21
GSE20123 ACOT7 11332 3 5 22
GSE43470 ACOT7 11332 6 5 32
GSE46452 ACOT7 11332 7 1 51
GSE47630 ACOT7 11332 8 4 28
GSE54993 ACOT7 11332 3 2 65
GSE54994 ACOT7 11332 14 3 36
GSE60625 ACOT7 11332 0 0 11
GSE74703 ACOT7 11332 5 3 28
GSE74704 ACOT7 11332 3 0 17
TCGA ACOT7 11332 12 22 62

Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.  

 

Somatic mutations of ACOT7:

 

Generating mutation plots.

 

Highly correlated genes for ACOT7:

 

Showing top 20/1974 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ACOT7PSMB20.7696912012
ACOT7TMC80.75335303
ACOT7EBNA1BP20.747467303
ACOT7EIF1AD0.737712303
ACOT7ARPC1B0.73468711011
ACOT7ZNF5980.734146404
ACOT7DHRS130.72945303
ACOT7NTMT10.727621606
ACOT7PSMG30.717974707
ACOT7NOP560.71591303
ACOT7UBE2C0.71261112012
ACOT7RCC20.7104505
ACOT7USB10.70989710010
ACOT7NADSYN10.709173303
ACOT7ADRM10.70770712011
ACOT7CKS1B0.7073711011
ACOT7XPR10.707032707
ACOT7PLAU0.70344811010
ACOT7LRRC8C0.701887303
ACOT7CDC200.70121812011

For details and further investigation, click here