| Full name: ribosomal protein S23 | Alias Symbol: S23|uS12 | ||
| Type: protein-coding gene | Cytoband: 5q14.2 | ||
| Entrez ID: 6228 | HGNC ID: HGNC:10410 | Ensembl Gene: ENSG00000186468 | OMIM ID: 603683 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPS23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS23 | 6228 | 200926_at | -0.1349 | 0.5138 | |
| GSE20347 | RPS23 | 6228 | 200926_at | -0.1383 | 0.0939 | |
| GSE23400 | RPS23 | 6228 | 200926_at | -0.0410 | 0.4064 | |
| GSE26886 | RPS23 | 6228 | 200926_at | 0.0591 | 0.6891 | |
| GSE29001 | RPS23 | 6228 | 200926_at | -0.2061 | 0.2898 | |
| GSE38129 | RPS23 | 6228 | 200926_at | -0.1571 | 0.0229 | |
| GSE45670 | RPS23 | 6228 | 200926_at | -0.2397 | 0.0018 | |
| GSE53622 | RPS23 | 6228 | 45285 | -0.6878 | 0.0000 | |
| GSE53624 | RPS23 | 6228 | 45285 | -0.7665 | 0.0000 | |
| GSE63941 | RPS23 | 6228 | 200926_at | 0.0817 | 0.4646 | |
| GSE77861 | RPS23 | 6228 | 200926_at | -0.1947 | 0.2455 | |
| GSE97050 | RPS23 | 6228 | A_32_P84605 | -0.2836 | 0.3485 | |
| SRP007169 | RPS23 | 6228 | RNAseq | -0.9321 | 0.0198 | |
| SRP008496 | RPS23 | 6228 | RNAseq | -0.9196 | 0.0005 | |
| SRP064894 | RPS23 | 6228 | RNAseq | -0.6503 | 0.0656 | |
| SRP133303 | RPS23 | 6228 | RNAseq | -0.6791 | 0.0002 | |
| SRP159526 | RPS23 | 6228 | RNAseq | -0.9610 | 0.0062 | |
| SRP193095 | RPS23 | 6228 | RNAseq | -1.2710 | 0.0000 | |
| SRP219564 | RPS23 | 6228 | RNAseq | -0.5378 | 0.0548 | |
| TCGA | RPS23 | 6228 | RNAseq | -0.0529 | 0.2666 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPS23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS23 | 6228 | 1 | 13 | 16 | |
| GSE20123 | RPS23 | 6228 | 1 | 13 | 16 | |
| GSE43470 | RPS23 | 6228 | 2 | 10 | 31 | |
| GSE46452 | RPS23 | 6228 | 0 | 28 | 31 | |
| GSE47630 | RPS23 | 6228 | 1 | 19 | 20 | |
| GSE54993 | RPS23 | 6228 | 8 | 1 | 61 | |
| GSE54994 | RPS23 | 6228 | 2 | 18 | 33 | |
| GSE60625 | RPS23 | 6228 | 0 | 0 | 11 | |
| GSE74703 | RPS23 | 6228 | 1 | 7 | 28 | |
| GSE74704 | RPS23 | 6228 | 1 | 6 | 13 | |
| TCGA | RPS23 | 6228 | 4 | 49 | 43 |
Total number of gains: 21; Total number of losses: 164; Total Number of normals: 303.
Somatic mutations of RPS23:
Generating mutation plots.
Highly correlated genes for RPS23:
Showing top 20/622 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS23 | AK4 | 0.838068 | 3 | 0 | 3 |
| RPS23 | GSTO2 | 0.765123 | 3 | 0 | 3 |
| RPS23 | JAK1 | 0.753569 | 3 | 0 | 3 |
| RPS23 | MR1 | 0.736144 | 3 | 0 | 3 |
| RPS23 | NSA2 | 0.730314 | 12 | 0 | 10 |
| RPS23 | SNN | 0.71596 | 3 | 0 | 3 |
| RPS23 | ZNF268 | 0.710823 | 3 | 0 | 3 |
| RPS23 | CGNL1 | 0.708061 | 3 | 0 | 3 |
| RPS23 | ANGPTL1 | 0.707309 | 4 | 0 | 4 |
| RPS23 | SLC2A4 | 0.705529 | 3 | 0 | 3 |
| RPS23 | TBCK | 0.705451 | 3 | 0 | 3 |
| RPS23 | ATXN10 | 0.702728 | 3 | 0 | 3 |
| RPS23 | CLEC3B | 0.702638 | 3 | 0 | 3 |
| RPS23 | SF3A1 | 0.700533 | 3 | 0 | 3 |
| RPS23 | BNIP3 | 0.698298 | 3 | 0 | 3 |
| RPS23 | GPBP1 | 0.692571 | 4 | 0 | 3 |
| RPS23 | GTF3C6 | 0.691139 | 3 | 0 | 3 |
| RPS23 | COX7C | 0.688493 | 12 | 0 | 12 |
| RPS23 | PPID | 0.688453 | 3 | 0 | 3 |
| RPS23 | SNX14 | 0.685779 | 3 | 0 | 3 |
For details and further investigation, click here
