MRPL15

 

Full name: mitochondrial ribosomal protein L15 Alias Symbol: RPML7|MRP-L7|HSPC145|L15mt|MRP-L15
Type: protein-coding gene Cytoband: 8q11.23
Entrez ID: 29088 HGNC ID: HGNC:14054 Ensembl Gene: ENSG00000137547 OMIM ID: 611828
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MRPL15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MRPL15 29088 218027_at 0.4800 0.1270
GSE20347 MRPL15 29088 218027_at 0.8254 0.0000
GSE23400 MRPL15 29088 218027_at 0.7773 0.0000
GSE26886 MRPL15 29088 218027_at 0.4175 0.0468
GSE29001 MRPL15 29088 218027_at 0.5408 0.1773
GSE38129 MRPL15 29088 218027_at 0.7888 0.0000
GSE45670 MRPL15 29088 218027_at 0.5709 0.0187
GSE53622 MRPL15 29088 46631 0.5455 0.0000
GSE53624 MRPL15 29088 46631 0.6820 0.0000
GSE63941 MRPL15 29088 218027_at 0.4020 0.3640
GSE77861 MRPL15 29088 218027_at 0.3577 0.1882
GSE97050 MRPL15 29088 A_23_P94174 0.2158 0.4016
SRP007169 MRPL15 29088 RNAseq 0.1737 0.7247
SRP008496 MRPL15 29088 RNAseq 0.2194 0.4862
SRP064894 MRPL15 29088 RNAseq 0.7142 0.0035
SRP133303 MRPL15 29088 RNAseq 0.5347 0.0000
SRP159526 MRPL15 29088 RNAseq 0.4069 0.2111
SRP193095 MRPL15 29088 RNAseq 0.1162 0.3837
SRP219564 MRPL15 29088 RNAseq 0.3455 0.3595
TCGA MRPL15 29088 RNAseq 0.1271 0.0279

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MRPL15 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MRPL15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MRPL15 29088 14 2 14
GSE20123 MRPL15 29088 14 2 14
GSE43470 MRPL15 29088 13 3 27
GSE46452 MRPL15 29088 20 3 36
GSE47630 MRPL15 29088 23 1 16
GSE54993 MRPL15 29088 1 16 53
GSE54994 MRPL15 29088 28 0 25
GSE60625 MRPL15 29088 0 4 7
GSE74703 MRPL15 29088 12 2 22
GSE74704 MRPL15 29088 10 0 10
TCGA MRPL15 29088 42 9 45

Total number of gains: 177; Total number of losses: 42; Total Number of normals: 269.  

 

Somatic mutations of MRPL15:

 

Generating mutation plots.

 

Highly correlated genes for MRPL15:

 

Showing top 20/1049 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MRPL15MRPL130.72313211011
MRPL15MRPS280.7095041009
MRPL15PRKDC0.69371412011
MRPL15TCEA10.68866111010
MRPL15MTDH0.68633411011
MRPL15COPS50.67980611011
MRPL15ENY20.67965311011
MRPL15PUF600.6703291008
MRPL15POC1A0.666555303
MRPL15TACO10.666244909
MRPL15CHEK10.66566812010
MRPL15MPLKIP0.665384605
MRPL15CCT50.663827707
MRPL15ATP6V1C10.6609421108
MRPL15NUP370.65892111010
MRPL15TMEM700.658859807
MRPL15ARMC10.65713410010
MRPL15DHX370.656866404
MRPL15TGS10.65657811010
MRPL15CDK40.65631610010

For details and further investigation, click here