| Full name: trefoil factor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 7032 | HGNC ID: HGNC:11756 | Ensembl Gene: ENSG00000160181 | OMIM ID: 182590 |
| Drug and gene relationship at DGIdb | |||
Expression of TFF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TFF2 | 7032 | 214476_at | -0.1566 | 0.7319 | |
| GSE20347 | TFF2 | 7032 | 214476_at | 0.0056 | 0.9408 | |
| GSE23400 | TFF2 | 7032 | 214476_at | -0.3353 | 0.0087 | |
| GSE26886 | TFF2 | 7032 | 214476_at | 0.4085 | 0.0311 | |
| GSE29001 | TFF2 | 7032 | 214476_at | 0.0481 | 0.7771 | |
| GSE38129 | TFF2 | 7032 | 214476_at | -0.4803 | 0.1395 | |
| GSE45670 | TFF2 | 7032 | 214476_at | -0.2889 | 0.2220 | |
| GSE53622 | TFF2 | 7032 | 8867 | -0.7607 | 0.0370 | |
| GSE53624 | TFF2 | 7032 | 8867 | -0.8136 | 0.0123 | |
| GSE63941 | TFF2 | 7032 | 214476_at | 0.2714 | 0.1816 | |
| GSE77861 | TFF2 | 7032 | 214476_at | -0.0646 | 0.6045 | |
| GSE97050 | TFF2 | 7032 | A_23_P57364 | -0.1051 | 0.6965 | |
| TCGA | TFF2 | 7032 | RNAseq | -4.9090 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TFF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TFF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TFF2 | 7032 | 2 | 8 | 20 | |
| GSE20123 | TFF2 | 7032 | 2 | 8 | 20 | |
| GSE43470 | TFF2 | 7032 | 0 | 13 | 30 | |
| GSE46452 | TFF2 | 7032 | 1 | 21 | 37 | |
| GSE47630 | TFF2 | 7032 | 6 | 17 | 17 | |
| GSE54993 | TFF2 | 7032 | 8 | 1 | 61 | |
| GSE54994 | TFF2 | 7032 | 3 | 8 | 42 | |
| GSE60625 | TFF2 | 7032 | 0 | 0 | 11 | |
| GSE74703 | TFF2 | 7032 | 0 | 10 | 26 | |
| GSE74704 | TFF2 | 7032 | 1 | 4 | 15 | |
| TCGA | TFF2 | 7032 | 7 | 40 | 49 |
Total number of gains: 30; Total number of losses: 130; Total Number of normals: 328.
Somatic mutations of TFF2:
Generating mutation plots.
Highly correlated genes for TFF2:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TFF2 | LINC00261 | 0.773625 | 3 | 0 | 3 |
| TFF2 | CTSE | 0.709677 | 5 | 0 | 4 |
| TFF2 | TFF1 | 0.703459 | 10 | 0 | 8 |
| TFF2 | SULT1C2 | 0.691372 | 5 | 0 | 4 |
| TFF2 | CAPN8 | 0.690111 | 5 | 0 | 5 |
| TFF2 | SSTR5-AS1 | 0.675617 | 3 | 0 | 3 |
| TFF2 | KRT20 | 0.672691 | 6 | 0 | 5 |
| TFF2 | PGC | 0.653503 | 5 | 0 | 4 |
| TFF2 | SPINK1 | 0.651015 | 5 | 0 | 3 |
| TFF2 | CAPN9 | 0.648221 | 8 | 0 | 6 |
| TFF2 | GKN1 | 0.638148 | 6 | 0 | 4 |
| TFF2 | KCNE2 | 0.636261 | 5 | 0 | 4 |
| TFF2 | LGALS4 | 0.630081 | 6 | 0 | 4 |
| TFF2 | MS4A8 | 0.620664 | 4 | 0 | 3 |
| TFF2 | CHIA | 0.61353 | 6 | 0 | 4 |
| TFF2 | TMC5 | 0.613475 | 5 | 0 | 4 |
| TFF2 | PLA2G1B | 0.612298 | 5 | 0 | 3 |
| TFF2 | AZGP1 | 0.60892 | 6 | 0 | 5 |
| TFF2 | C6orf58 | 0.607432 | 5 | 0 | 4 |
| TFF2 | UGT2B15 | 0.598546 | 4 | 0 | 4 |
For details and further investigation, click here
